Tea polyphenol (−)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines MZ Fang, Y Wang, N Ai, Z Hou, Y Sun, H Lu, W Welsh, CS Yang Cancer research 63 (22), 7563-7570, 2003 | 1337 | 2003 |
Stability, cellular uptake, biotransformation, and efflux of tea polyphenol (−)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells J Hong, H Lu, X Meng, JH Ryu, Y Hara, CS Yang Cancer Research 62 (24), 7241-7246, 2002 | 521 | 2002 |
Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (−)-epigallocatechin gallate H Lu, X Meng, CS Yang Drug metabolism and disposition 31 (5), 572-579, 2003 | 397 | 2003 |
Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice X Meng, P Maliakal, H Lu, MJ Lee, CS Yang Journal of agricultural and food chemistry 52 (4), 935-942, 2004 | 374 | 2004 |
Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats X Meng, S Sang, N Zhu, H Lu, S Sheng, MJ Lee, CT Ho, CS Yang Chemical research in toxicology 15 (8), 1042-1050, 2002 | 338 | 2002 |
Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice JD Lambert, MJ Lee, H Lu, X Meng, JJJ Hong, DN Seril, CS Yang, ... The Journal of nutrition 133 (12), 4172-4177, 2003 | 337 | 2003 |
Glucuronides of tea catechins: enzymology of biosynthesis and biological activities H Lu, X Meng, C Li, S Sang, C Patten, S Sheng, J Hong, N Bai, B Winnik, ... Drug metabolism and disposition 31 (4), 452-461, 2003 | 306 | 2003 |
Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract MJ Lee, JD Lambert, S Prabhu, X Meng, H Lu, P Maliakal, CT Ho, ... Cancer Epidemiology Biomarkers & Prevention 13 (1), 132-137, 2004 | 226 | 2004 |
Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR H Lu, S Choudhuri, K Ogura, IL Csanaky, X Lei, X Cheng, P Song, ... Toxicological sciences 103 (1), 35-45, 2008 | 190 | 2008 |
Analysis of urinary metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry C Li, X Meng, B Winnik, MJ Lee, H Lu, S Sheng, B Buckley, CS Yang Chemical research in toxicology 14 (6), 702-707, 2001 | 163 | 2001 |
Tissue distribution of concentrative and equilibrative nucleoside transporters in male and female rats and mice H Lu, C Chen, C Klaassen Drug Metabolism and Disposition 32 (12), 1455-1461, 2004 | 155 | 2004 |
Organic anion–transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2‐null mice IL Csanaky, H Lu, Y Zhang, K Ogura, S Choudhuri, CD Klaassen Hepatology 53 (1), 272-281, 2011 | 138 | 2011 |
Xenobiotic transporters: ascribing function from gene knockout and mutation studies CD Klaassen, H Lu Toxicological sciences 101 (2), 186-196, 2008 | 134 | 2008 |
Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents H Lu, C Klaassen Peptides 27 (4), 850-857, 2006 | 123 | 2006 |
Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures J Liu, H Lu, YF Lu, X Lei, JY Cui, E Ellis, SC Strom, CD Klaassen Toxicological Sciences 141 (2), 538-546, 2014 | 107 | 2014 |
Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver–insights into mechanisms of hepatic steatosis HJ Renaud, JY Cui, H Lu, CD Klaassen PloS one 9 (2), e88584, 2014 | 103 | 2014 |
Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipids H Lu Acta Pharmaceutica Sinica B 6 (5), 393-408, 2016 | 102 | 2016 |
Nrf2 protects against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis H Lu, W Cui, CD Klaassen Toxicology and applied pharmacology 256 (2), 122-135, 2011 | 92 | 2011 |
Gender differences in mRNA expression of ATP-binding cassette efflux and bile acid transporters in kidney, liver, and intestine of 5/6 nephrectomized rats H Lu, C Klaassen Drug Metabolism and Disposition 36 (1), 16-23, 2008 | 73 | 2008 |
Alterations in hepatic mRNA expression of phase II enzymes and xenobiotic transporters after targeted disruption of hepatocyte nuclear factor 4 alpha H Lu, FJ Gonzalez, C Klaassen Toxicological Sciences 118 (2), 380-390, 2010 | 69 | 2010 |