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Dana J Philpott
Dana J Philpott
Professor, Immunology, University of Toronto
在 utoronto.ca 的电子邮件经过验证
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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
SE Girardin, IG Boneca, J Viala, M Chamaillard, A Labigne, G Thomas, ...
Journal of Biological Chemistry 278 (11), 8869-8872, 2003
30152003
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
SE Girardin, IG Boneca, LAM Carneiro, A Antignac, M Jehanno, J Viala, ...
Science 300 (5625), 1584-1587, 2003
19552003
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
LH Travassos, LAM Carneiro, M Ramjeet, S Hussey, YG Kim, ...
Nature immunology 11 (1), 55-62, 2010
15512010
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
J Viala, C Chaput, IG Boneca, A Cardona, SE Girardin, AP Moran, ...
Nature immunology 5 (11), 1166-1174, 2004
15122004
Nod-like proteins in immunity, inflammation and disease
JH Fritz, RL Ferrero, DJ Philpott, SE Girardin
Nature immunology 7 (12), 1250-1257, 2006
11232006
The NLR gene family: a standard nomenclature
JPY Ting, RC Lovering, ES Alnemri, J Bertin, JM Boss, BK Davis, ...
Immunity 28 (3), 285-287, 2008
10732008
Bacterial infection causes stress-induced memory dysfunction in mice
MG Gareau, E Wine, DM Rodrigues, JH Cho, MT Whary, DJ Philpott, ...
Gut 60 (3), 307-317, 2011
10642011
Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2
SE Girardin, LH Travassos, M Hervé, D Blanot, IG Boneca, DJ Philpott, ...
Journal of Biological Chemistry 278 (43), 41702-41708, 2003
8842003
CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri
SE Girardin, R Tournebize, M Mavris, AL Page, X Li, GR Stark, J Bertin, ...
EMBO reports, 2001
7822001
NOD proteins: regulators of inflammation in health and disease
DJ Philpott, MT Sorbara, SJ Robertson, K Croitoru, SE Girardin
Nature Reviews Immunology 14 (1), 9-23, 2014
7272014
Recognition of Staphylococcus aureus by the Innate Immune System
B Fournier, DJ Philpott
Clinical microbiology reviews 18 (3), 521-540, 2005
6952005
Modulating immunity as a therapy for bacterial infections
REW Hancock, A Nijnik, DJ Philpott
Nature Reviews Microbiology 10 (4), 243-254, 2012
6282012
Toll‐like receptor 2‐dependent bacterial sensing does not occur via peptidoglycan recognition
LH Travassos, SE Girardin, DJ Philpott, D Blanot, MA Nahori, C Werts, ...
EMBO reports 5 (10), 1000-1006, 2004
6182004
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells
M Kaparakis, L Turnbull, L Carneiro, S Firth, HA Coleman, HC Parkington, ...
Cellular microbiology 12 (3), 372-385, 2010
4672010
Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells
A Belcheva, T Irrazabal, SJ Robertson, C Streutker, H Maughan, S Rubino, ...
Cell 158 (2), 288-299, 2014
4632014
Synergistic stimulation of human monocytes and dendritic cells by Toll‐like receptor 4 and NOD1‐and NOD2‐activating agonists
JH Fritz, SE Girardin, C Fitting, C Werts, D Mengin‐Lecreulx, M Caroff, ...
European journal of immunology 35 (8), 2459-2470, 2005
4612005
Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation
M Chamaillard, SE Girardin, J Viala, DJ Philpott
Cellular microbiology 5 (9), 581-592, 2003
4442003
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system
IG Boneca, O Dussurget, D Cabanes, MA Nahori, S Sousa, M Lecuit, ...
Proceedings of the National Academy of Sciences 104 (3), 997-1002, 2007
4242007
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity
JH Fritz, L Le Bourhis, G Sellge, JG Magalhaes, H Fsihi, TA Kufer, ...
Immunity 26 (4), 445-459, 2007
4102007
Conversion of PtdIns (4, 5) P2 into PtdIns (5) P by the S. flexneri effector IpgD reorganizes host cell morphology
K Niebuhr, S Giuriato, T Pedron, DJ Philpott, F Gaits, J Sable, MP Sheetz, ...
The EMBO journal, 2002
4072002
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