| Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation KLH Wu, SHH Chan, JYH Chan Journal of neuroinflammation 9, 1-15, 2012 | 199 | 2012 |
| Oxidative impairment of mitochondrial electron transport chain complexes in rostral ventrolateral medulla contributes to neurogenic hypertension SHH Chan, KLH Wu, AYW Chang, MH Tai, JYH Chan Hypertension 53 (2), 217-227, 2009 | 146 | 2009 |
| Increased superoxide anion in rostral ventrolateral medulla contributes to hypertension in spontaneously hypertensive rats via interactions with nitric oxide MH Tai, LL Wang, KLH Wu, JYH Chan Free radical biology and medicine 38 (4), 450-462, 2005 | 102 | 2005 |
| Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension SHH Chan, CA Wu, KLH Wu, YH Ho, AYW Chang, JYH Chan Circulation research 105 (9), 886-896, 2009 | 98 | 2009 |
| Melatonin prevents maternal fructose intake‐induced programmed hypertension in the offspring: roles of nitric oxide and arachidonic acid metabolites YL Tain, S Leu, KLH Wu, WC Lee, JYH Chan Journal of pineal research 57 (1), 80-89, 2014 | 93 | 2014 |
| Oral intake of rosiglitazone promotes a central antihypertensive effect via upregulation of peroxisome proliferator-activated receptor-γ and alleviation of oxidative stress in … SHH Chan, KLH Wu, PSS Kung, JYH Chan Hypertension 55 (6), 1444-1453, 2010 | 83 | 2010 |
| Resveratrol prevents the development of hypertension programmed by maternal plus post‐weaning high‐fructose consumption through modulation of oxidative stress, nutrient‐sensing … YL Tain, WC Lee, KLH Wu, S Leu, JYH Chan Molecular Nutrition & Food Research 62 (15), 1800066, 2018 | 76 | 2018 |
| Nitric oxide-and superoxide-dependent mitochondrial signaling in endotoxin-induced apoptosis in the rostral ventrolateral medulla of rats SHH Chan, KLH Wu, LL Wang, JYH Chan Free Radical Biology and Medicine 39 (5), 603-618, 2005 | 72 | 2005 |
| Maternal fructose-intake-induced renal programming in adult male offspring YL Tain, KLH Wu, WC Lee, S Leu, JYH Chan The Journal of Nutritional Biochemistry 26 (6), 642-650, 2015 | 67 | 2015 |
| Impaired Nrf2 regulation of mitochondrial biogenesis in rostral ventrolateral medulla on hypertension induced by systemic inflammation KLH Wu, CW Wu, YM Chao, CY Hung, JYH Chan Free Radical Biology and Medicine 97, 58-74, 2016 | 63 | 2016 |
| Reduced functional expression and molecular synthesis of inducible nitric oxide synthase in rostral ventrolateral medulla of spontaneously hypertensive rats JYH Chan, LL Wang, KLH Wu, SHH Chan Circulation 104 (14), 1676-1681, 2001 | 55 | 2001 |
| Role of nitric oxide synthase uncoupling at rostral ventrolateral medulla in redox-sensitive hypertension associated with metabolic syndrome KLH Wu, YM Chao, SJ Tsay, CH Chen, SHH Chan, I Dovinova, JYH Chan Hypertension 64 (4), 815-824, 2014 | 52 | 2014 |
| Expression of pro-inflammatory cytokine and caspase genes promotes neuronal apoptosis in pontine reticular formation after spinal cord transection KLH Wu, SHH Chan, YM Chao, JYH Chan Neurobiology of disease 14 (1), 19-31, 2003 | 52 | 2003 |
| Impairment of the mitochondrial respiratory enzyme activity triggers sequential activation of apoptosis‐inducing factor‐dependent and caspase‐dependent signaling pathways to … KLH Wu, C Hsu, JYH Chan Journal of neurochemistry 101 (6), 1552-1566, 2007 | 51 | 2007 |
| Redox-sensitive oxidation and phosphorylation of PTEN contribute to enhanced activation of PI3K/Akt signaling in rostral ventrolateral medulla and neurogenic hypertension in … KLH Wu, CA Wu, CW Wu, SHH Chan, AYW Chang, JYH Chan Antioxidants & Redox Signaling 18 (1), 36-50, 2013 | 49 | 2013 |
| Translational insights on developmental origins of metabolic syndrome: Focus on fructose consumption WC Lee, KLH Wu, S Leu, YL Tain biomedical journal 41 (2), 96-101, 2018 | 46 | 2018 |
| Aliskiren administration during early postnatal life sex-specifically alleviates hypertension programmed by maternal high fructose consumption CN Hsu, KLH Wu, WC Lee, S Leu, JYH Chan, YL Tain Frontiers in physiology 7, 299, 2016 | 46 | 2016 |
| Maternal high fructose intake increases the vulnerability to post-weaning high-fat diet-induced programmed hypertension in male offspring YL Tain, WC Lee, KLH Wu, S Leu, JYH Chan Nutrients 10 (1), 56, 2018 | 37 | 2018 |
| High salt exacerbates programmed hypertension in maternal fructose-fed male offspring YL Tain, WC Lee, S Leu, K Wu, J Chan Nutrition, Metabolism and Cardiovascular Diseases 25 (12), 1146-1151, 2015 | 37 | 2015 |
| Nrf2 activation attenuates the early suppression of mitochondrial respiration due to the α-synuclein overexpression MH Fu, CW Wu, YC Lee, CY Hung, IC Chen, KLH Wu Biomedical journal 41 (3), 169-183, 2018 | 35 | 2018 |
