Structural analysis of leader peptide binding enables leader-free cyanobactin processing J Koehnke, G Mann, AF Bent, H Ludewig, S Shirran, C Botting, T Lebl, ... Nature chemical biology 11 (8), 558-563, 2015 | 178 | 2015 |
A marine viral halogenase that iodinates diverse substrates DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ... Nature chemistry 11 (12), 1091-1097, 2019 | 76 | 2019 |
Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates CM Czekster, H Ludewig, SA McMahon, JH Naismith Nature communications 8 (1), 1045, 2017 | 43 | 2017 |
Characterization of the fast and promiscuous macrocyclase from plant PCY1 enables the use of simple substrates H Ludewig, CM Czekster, E Oueis, ES Munday, M Arshad, SA Synowsky, ... ACS chemical biology 13 (3), 801-811, 2018 | 33 | 2018 |
Halogenases: structures and functions H Ludewig, S Molyneux, S Ferrinho, K Guo, R Lynch, DS Gkotsi, ... Current Opinion in Structural Biology 65, 51-60, 2020 | 27 | 2020 |
Derivatisable cyanobactin analogues: a semisynthetic approach E Oueis, C Adamson, G Mann, H Ludewig, P Redpath, M Migaud, ... ChemBioChem 16 (18), 2646-2650, 2015 | 23 | 2015 |
A biophysical framework for double-drugging kinases C Kim, H Ludewig, A Hadzipasic, S Kutter, V Nguyen, D Kern Proceedings of the National Academy of Sciences 120 (34), e2304611120, 2023 | 8 | 2023 |
A marine viral halogenase that iodinates diverse substrates. Nat Chem 11: 1091–1097 DS Gkotsi, H Ludewig, SV Sharma, JA Connolly, J Dhaliwal, Y Wang, ... | 7 | 2019 |
Dual-Action Kinase Inhibitors Control p38α MAP Kinase Threonine Dephosphorylation E Stadnicki, H Ludewig, RP Kumar, X Wang, Y Qiao, D Kern, N Bradshaw bioRxiv, 2024.05. 15.594272, 2024 | | 2024 |
A biophysical framework for the double-drugging of kinases H Ludewig, C Kim, A Hadzipasic, S Kutter, V Nguyen, D Kern PROTEIN SCIENCE 32 (12), 2023 | | 2023 |
Macrocyclisation Tags CM Czekster, H Ludewig, JH Naismith US Patent App. 16/644,885, 2020 | | 2020 |
Structural and Functional Characterization of Enzymes Promising Biocatalytic Prowess H Ludewig University of St Andrews, 2020 | | 2020 |
Macrocyclisation tags CM CZEKSTER, H Ludewig, JH NAISMITH | | 2019 |
Eukaryotic macrocyclases enhance biocatalytic production of cyclic peptides H Ludewig, C Czekster, J Naismith Journal of Peptide Science 24 (S2), 2018 | | 2018 |
Understanding and manipulating non-templated peptide bond formation by macrocyclase enzymes C Czekster, H Ludewig, SA McMahon, JH Naismith | | 2017 |
A novel macrocyclase H Ludewig, J Naismith Journal of Peptide Science 22 (S2), 2016 | | 2016 |