Integration of multi-omics data from mouse diversity panel highlights mitochondrial dysfunction in non-alcoholic fatty liver disease KC Krishnan, Z Kurt, R Barrere-Cain, S Sabir, A Das, R Floyd, L Vergnes, ... Cell systems 6 (1), 103-115. e7, 2018 | 131 | 2018 |
Sex differences in metabolism and cardiometabolic disorders KC Krishnan, M Mehrabian, AJ Lusis Current opinion in lipidology 29 (5), 404-410, 2018 | 104 | 2018 |
Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits F Norheim, Y Hasin-Brumshtein, L Vergnes, KC Krishnan, C Pan, ... Cell metabolism 29 (4), 932-949. e4, 2019 | 89 | 2019 |
A strategy for discovery of endocrine interactions with application to whole-body metabolism MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ... Cell metabolism 27 (5), 1138-1155. e6, 2018 | 70 | 2018 |
The genetic architecture of diet‐induced hepatic fibrosis in mice ST Hui, Z Kurt, I Tuominen, F Norheim, R C. Davis, C Pan, DL Dirks, ... Hepatology 68 (6), 2182-2196, 2018 | 66 | 2018 |
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity R Acín-Pérez, S Iborra, Y Martí-Mateos, ECL Cook, R Conde-Garrosa, ... Nature metabolism 2 (9), 974-988, 2020 | 50 | 2020 |
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle PJ Ferrara, X Rong, JA Maschek, ARP Verkerke, P Siripoksup, H Song, ... The Journal of clinical investigation 131 (8), 2021 | 48 | 2021 |
Sex-specific metabolic functions of adipose Lipocalin-2 KC Krishnan, S Sabir, M Shum, Y Meng, R Acín-Pérez, JM Lang, ... Molecular Metabolism 30, 30-47, 2019 | 48 | 2019 |
Sex differences in heart mitochondria regulate diastolic dysfunction Y Cao, L Vergnes, YC Wang, C Pan, K Chella Krishnan, TM Moore, ... Nature communications 13 (1), 3850, 2022 | 43 | 2022 |
Liver pyruvate kinase promotes NAFLD/NASH in both mice and humans in a sex-specific manner KC Krishnan, RR Floyd, S Sabir, DW Jayasekera, PV Leon-Mimila, ... Cellular and molecular gastroenterology and hepatology 11 (2), 389-406, 2021 | 40 | 2021 |
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2 K Chella Krishnan, L Vergnes, R Acín-Pérez, L Stiles, M Shum, L Ma, ... Nature metabolism 3 (11), 1552-1568, 2021 | 38 | 2021 |
Genetic architecture of group A streptococcal necrotizing soft tissue infections in the mouse K Chella Krishnan, S Mukundan, J Alagarsamy, J Hur, S Nookala, ... PLoS pathogens 12 (7), e1005732, 2016 | 35 | 2016 |
A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains S Mairpady Shambat, N Siemens, IR Monk, DB Mohan, S Mukundan, ... Scientific reports 6 (1), 31360, 2016 | 34 | 2016 |
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity M Shum, CA Shintre, T Althoff, V Gutierrez, M Segawa, AD Saxberg, ... Science translational medicine 13 (594), eabd1869, 2021 | 31 | 2021 |
Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR [S] F Norheim, T Bjellaas, ST Hui, KC Krishnan, J Lee, S Gupta, C Pan, ... Journal of lipid research 59 (7), 1164-1174, 2018 | 29 | 2018 |
Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice G Zhang, HR Byun, Z Ying, M Blencowe, Y Zhao, J Hong, L Shu, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (1), 165569, 2020 | 28 | 2020 |
Metal-mediated modulation of streptococcal cysteine protease activity and its biological implications K Chella Krishnan, S Mukundan, JA Landero Figueroa, JA Caruso, ... Infection and Immunity 82 (7), 2992-3001, 2014 | 23 | 2014 |
Recruitment and remodeling of peridroplet mitochondria in human adipose tissue R Acín-Perez, A Petcherski, M Veliova, IY Benador, EA Assali, ... Redox Biology 46, 102087, 2021 | 18 | 2021 |
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis F Norheim, K Chella Krishnan, T Bjellaas, L Vergnes, C Pan, BW Parks, ... Molecular systems biology 17 (1), e9684, 2021 | 17 | 2021 |
Host genetic variations and sex differences potentiate predisposition, severity, and outcomes of group A Streptococcus-mediated necrotizing soft tissue infections K Chella Krishnan, S Mukundan, J Alagarsamy, D Laturnus, M Kotb Infection and immunity 84 (2), 416-424, 2016 | 13 | 2016 |