The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway OA Coso, M Chiariello, JC Yu, H Teramoto, P Crespo, N Xu, T Miki, ... Cell 81 (7), 1137-1146, 1995 | 2152 | 1995 |
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate O Cuvillier, G Pirianov, B Kleuser, PG Vanek, OA Coso, JS Gutkind, ... Nature 381 (6585), 800-803, 1996 | 1907 | 1996 |
G-protein-coupled receptors and cancer RT Dorsam, JS Gutkind Nature reviews cancer 7 (2), 79-94, 2007 | 1716 | 2007 |
Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. S Miyamoto, H Teramoto, OA Coso, JS Gutkind, PD Burbelo, SK Akiyama, ... The Journal of cell biology 131 (3), 791-805, 1995 | 1540 | 1995 |
G-protein-coupled receptors and signaling networks: emerging paradigms MJ Marinissen, JS Gutkind Trends in pharmacological sciences 22 (7), 368-376, 2001 | 1448 | 2001 |
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin J Gavard, JS Gutkind Nature cell biology 8 (11), 1223-1234, 2006 | 1246 | 2006 |
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-ß-catenin signaling axis MD Castellone, H Teramoto, BO Williams, KM Druey, JS Gutkind Science 310 (5753), 1504-1510, 2005 | 1115 | 2005 |
Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits P Crespo, N Xu, WF Simonds, JS Gutkind Nature 369 (6479), 418-420, 1994 | 1078 | 1994 |
The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades JS Gutkind Journal of Biological Chemistry 273 (4), 1839-1842, 1998 | 1027 | 1998 |
G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator C Bais, B Santomasso, O Coso, L Arvanitakis, EG Raaka, JS Gutkind, ... Nature 391 (6662), 86-89, 1998 | 1016 | 1998 |
Targeted Killing of Cancer Cells in Vivo and in Vitro with EGF-Directed Carbon Nanotube-Based Drug Delivery AA Bhirde, V Patel, J Gavard, G Zhang, AA Sousa, A Masedunskas, ... ACS nano 3 (2), 307-316, 2009 | 993 | 2009 |
Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. S Miyamoto, H Teramoto, JS Gutkind, KM Yamada The Journal of cell biology 135 (6), 1633-1642, 1996 | 983 | 1996 |
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product P Crespo, KE Schuebel, AA Ostrom, JS Gutkind, XR Bustelo Nature 385 (6612), 169-172, 1997 | 978 | 1997 |
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ M Lopez-Ilasaca, P Crespo, PG Pellici, JS Gutkind, R Wetzker Science 275 (5298), 394-397, 1997 | 875 | 1997 |
Augmented Wnt signaling in a mammalian model of accelerated aging H Liu, MM Fergusson, RM Castilho, J Liu, L Cao, J Chen, D Malide, ... Science 317 (5839), 803-806, 2007 | 866 | 2007 |
Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers X Yu, B Munge, V Patel, G Jensen, A Bhirde, JD Gong, SN Kim, ... Journal of the American Chemical Society 128 (34), 11199-11205, 2006 | 784 | 2006 |
G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension A Wirth, Z Benyó, M Lukasova, B Leutgeb, N Wettschureck, S Gorbey, ... Nature medicine 14 (1), 64-68, 2008 | 728 | 2008 |
Cbl-b regulates the CD28 dependence of T-cell activation YJ Chiang, HK Kole, K Brown, M Naramura, S Fukuhara, RJ Hu, IK Jang, ... Nature 403 (6766), 216-220, 2000 | 719 | 2000 |
Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer JF Rusling, CV Kumar, JS Gutkind, V Patel Analyst 135 (10), 2496-2511, 2010 | 629 | 2010 |
Regulation of reactive-oxygen-species generation in fibroblasts by Rac 1 M Sundaresan, ZX Yu, VJ Ferrans, DJ Sulciner, S GUTKIND, KJ IRANI, ... Biochemical Journal 318 (2), 379-382, 1996 | 617 | 1996 |