Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression VV Panchal, C Griffiths, H Mosaei, B Bilyk, JAF Sutton, OT Carnell, ... PLoS pathogens 16 (7), e1008672, 2020 | 67 | 2020 |
Mechanisms of antibiotics inhibiting bacterial RNA polymerase H Mosaei, J Harbottle Biochemical Society Transactions 47 (1), 339-350, 2019 | 61 | 2019 |
Mode of action of kanglemycin A, an ansamycin natural product that is active against rifampicin-resistant Mycobacterium tuberculosis H Mosaei, V Molodtsov, B Kepplinger, J Harbottle, CW Moon, RE Jeeves, ... Molecular cell 72 (2), 263-274. e5, 2018 | 59 | 2018 |
Structural reassignment and absolute stereochemistry of madurastatin C1 (MBJ-0034) and the related aziridine siderophores: madurastatins A1, B1, and MBJ-0035 AR Tyler, H Mosaei, S Morton, PG Waddell, C Wills, W McFarlane, J Gray, ... Journal of natural products 80 (5), 1558-1562, 2017 | 35 | 2017 |
Inhibition of RNA polymerase by rifampicin and rifamycin-like molecules H Mosaei, N Zenkin EcoSal Plus 9 (1), 10.1128/ecosalplus. ESP-0017-2019, 2020 | 33 | 2020 |
Two distinct pathways of RNA polymerase backtracking determine the requirement for the Trigger Loop during RNA hydrolysis H Mosaei, N Zenkin Nucleic acids research 49 (15), 8777-8784, 2021 | 14 | 2021 |
Recurrent Drug-Induced Hepatitis in Tuberculosis—Comparison of Two Drug Regimens M Shamaei, M Mirsaeidi, P Baghaei, H Mosaei, M Marjani, P Tabarsi American journal of therapeutics 24 (2), e144-e149, 2017 | 7 | 2017 |
Translation selectively destroys non-functional transcription complexes J Woodgate, H Mosaei, P Brazda, F Stevenson-Jones, N Zenkin Nature 626 (8000), 891-896, 2024 | 5 | 2024 |
Kanglemycin a can overcome rifamycin resistance caused by ADP-ribosylation by arr protein J Harbottle, H Mosaei, N Allenby, N Zenkin Antimicrobial Agents and Chemotherapy 65 (12), 10.1128/aac. 00864-21, 2021 | 5 | 2021 |