| Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin S Aschemeyer, B Qiao, D Stefanova, EV Valore, AC Sek, TA Ruwe, ... Blood, The Journal of the American Society of Hematology 131 (8), 899-910, 2018 | 317 | 2018 |
| Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia P Ramos, C Casu, S Gardenghi, L Breda, BJ Crielaard, E Guy, ... Nature medicine 19 (4), 437-445, 2013 | 253 | 2013 |
| Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice S Guo, C Casu, S Gardenghi, S Booten, M Aghajan, R Peralta, A Watt, ... The Journal of clinical investigation 123 (4), 1531-1541, 2013 | 251 | 2013 |
| Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera C Casu, PR Oikonomidou, H Chen, V Nandi, Y Ginzburg, P Prasad, ... Blood, The Journal of the American Society of Hematology 128 (2), 265-276, 2016 | 150 | 2016 |
| FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis LM Coe, SV Madathil, C Casu, B Lanske, S Rivella, D Sitara Journal of Biological Chemistry 289 (14), 9795-9810, 2014 | 148 | 2014 |
| Hepcidin agonists as therapeutic tools C Casu, E Nemeth, S Rivella Blood, The Journal of the American Society of Hematology 131 (16), 1790-1794, 2018 | 145 | 2018 |
| DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia LKM Lam, S Murphy, D Kokkinaki, A Venosa, S Sherrill-Mix, C Casu, ... Science translational medicine 13 (616), eabj1008, 2021 | 141 | 2021 |
| The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice G Casanovas, MV Spasić, C Casu, S Rivella, J Strelau, K Unsicker, ... Haematologica 98 (3), 444, 2013 | 130 | 2013 |
| Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus S Gardenghi, TM Renaud, A Meloni, C Casu, BJ Crielaard, LM Bystrom, ... Blood, The Journal of the American Society of Hematology 123 (8), 1137-1145, 2014 | 115 | 2014 |
| Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients L Breda, C Casu, S Gardenghi, N Bianchi, L Cartegni, M Narla, ... PloS one 7 (3), e32345, 2012 | 110 | 2012 |
| Combination of Tmprss6-ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia C Casu, M Aghajan, PR Oikonomidou, S Guo, BP Monia, S Rivella Haematologica 101 (1), e8, 2016 | 81 | 2016 |
| Klotho deficiency disrupts hematopoietic stem cell development and erythropoiesis SV Madathil, LM Coe, C Casu, D Sitara The American journal of pathology 184 (3), 827-841, 2014 | 66 | 2014 |
| Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ... Nature communications 8 (1), 403, 2017 | 63 | 2017 |
| Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis P Ramos, E Guy, N Chen, CC Proenca, S Gardenghi, C Casu, A Follenzi, ... Blood, The Journal of the American Society of Hematology 117 (4), 1379-1389, 2011 | 60 | 2011 |
| Lack of Gdf11 does not improve anemia or prevent the activity of RAP-536 in a mouse model of β-thalassemia A Guerra, PR Oikonomidou, S Sinha, J Zhang, V Lo Presti, CR Hamilton, ... Blood, The Journal of the American Society of Hematology 134 (6), 568-572, 2019 | 56 | 2019 |
| Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major C Casu, R Chessa, A Liu, R Gupta, H Drakesmith, R Fleming, ... Haematologica 105 (7), 1835, 2020 | 48 | 2020 |
| Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis NL Parrow, Y Li, M Feola, A Guerra, C Casu, P Prasad, L Mammen, F Ali, ... Blood, The Journal of the American Society of Hematology 134 (17), 1373-1384, 2019 | 41 | 2019 |
| Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome RB Nowak, J Papoin, DS Gokhin, C Casu, S Rivella, JM Lipton, L Blanc, ... Blood, The Journal of the American Society of Hematology 130 (9), 1144-1155, 2017 | 40 | 2017 |
| Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity C Casu, M Pettinato, A Liu, M Aghajan, V Lo Presti, MR Lidonnici, ... Blood, The Journal of the American Society of Hematology 136 (17), 1968-1979, 2020 | 38 | 2020 |
| Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major C Casu, VL Presti, PR Oikonomidou, L Melchiori, O Abdulmalik, P Ramos, ... Haematologica 103 (2), e46, 2018 | 37 | 2018 |
