| Sirt1 protects against high-fat diet-induced metabolic damage PT Pfluger, D Herranz, S Velasco-Miguel, M Serrano, MH Tschöp Proceedings of the national academy of sciences 105 (28), 9793-9798, 2008 | 1123 | 2008 |
| Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer D Herranz, M Muñoz-Martin, M Cañamero, F Mulero, B Martinez-Pastor, ... Nature communications 1 (1), 3, 2010 | 719 | 2010 |
| GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK D Beiroa, M Imbernon, R Gallego, A Senra, D Herranz, F Villarroya, ... Diabetes 63 (10), 3346-3358, 2014 | 544 | 2014 |
| A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia D Herranz, A Ambesi-Impiombato, T Palomero, SA Schnell, L Belver, ... Nature medicine 20 (10), 1130-1137, 2014 | 432 | 2014 |
| SIRT1: recent lessons from mouse models D Herranz, M Serrano Nature Reviews Cancer 10 (12), 819-823, 2010 | 297 | 2010 |
| SIRT1 contributes to telomere maintenance and augments global homologous recombination JA Palacios, D Herranz, ML De Bonis, S Velasco, M Serrano, MA Blasco Journal of Cell Biology 191 (7), 1299-1313, 2010 | 284 | 2010 |
| Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia E Piovan, J Yu, V Tosello, D Herranz, A Ambesi-Impiombato, AC Da Silva, ... Cancer cell 24 (6), 766-776, 2013 | 282 | 2013 |
| Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia D Herranz, A Ambesi-Impiombato, J Sudderth, M Sánchez-Martín, ... Nature medicine 21 (10), 1182-1189, 2015 | 206 | 2015 |
| Sirtuin 1 regulation of developmental genes during differentiation of stem cells V Calvanese, E Lara, B Suárez-Álvarez, R Abu Dawud, ... Proceedings of the National Academy of Sciences 107 (31), 13736-13741, 2010 | 196 | 2010 |
| Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin A Efeyan, A Ortega-Molina, S Velasco-Miguel, D Herranz, LT Vassilev, ... Cancer research 67 (15), 7350-7357, 2007 | 170 | 2007 |
| Policing of oncogene activity by p53 A Efeyan, I Garcia-Cao, D Herranz, S Velasco-Miguel, M Serrano Nature 443 (7108), 159-159, 2006 | 141 | 2006 |
| Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia G Fabbri, AB Holmes, M Viganotti, C Scuoppo, L Belver, D Herranz, ... Proceedings of the National Academy of Sciences 114 (14), E2911-E2919, 2017 | 131 | 2017 |
| SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling JL García‐Rodríguez, L Barbier‐Torres, S Fernández‐Álvarez, ... Hepatology 59 (5), 1972-1983, 2014 | 123 | 2014 |
| Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK A Maraver, PJ Fernandez-Marcos, D Herranz, M Cañamero, ... Cancer cell 22 (2), 222-234, 2012 | 123 | 2012 |
| Slow TCA flux and ATP production in primary solid tumours but not metastases CR Bartman, DR Weilandt, Y Shen, WD Lee, Y Han, T TeSlaa, ... Nature 614 (7947), 349-357, 2023 | 114 | 2023 |
| The MYC enhancer-ome: long-range transcriptional regulation of MYC in cancer O Lancho, D Herranz Trends in cancer 4 (12), 810-822, 2018 | 107 | 2018 |
| SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency D Herranz, A Maraver, M Canamero, G Gomez-Lopez, L Inglada-Perez, ... Oncogene 32 (34), 4052-4056, 2013 | 89 | 2013 |
| SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia JC García-Cañaveras, O Lancho, GS Ducker, JM Ghergurovich, X Xu, ... Leukemia 35 (2), 377-388, 2021 | 84 | 2021 |
| Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer E Wauters, VJ Sanchez-Arevalo Lobo, AV Pinho, A Mawson, D Herranz, ... Cancer research 73 (7), 2357-2367, 2013 | 71 | 2013 |
| SIRT1 stabilizes PML promoting its sumoylation M Campagna, D Herranz, MA Garcia, L Marcos-Villar, ... Cell Death & Differentiation 18 (1), 72-79, 2011 | 70 | 2011 |
