| Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force K Wolf, M Te Lindert, M Krause, S Alexander, J Te Riet, AL Willis, ... Journal of Cell Biology 201 (7), 1069-1084, 2013 | 1425 | 2013 |
| A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy CA Schmitt, JS Fridman, M Yang, S Lee, E Baranov, RM Hoffman, ... Cell 109 (3), 335-346, 2002 | 1250 | 2002 |
| Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice M Kioi, H Vogel, G Schultz, RM Hoffman, GR Harsh, JM Brown The Journal of clinical investigation 120 (3), 694-705, 2010 | 872 | 2010 |
| The multiple uses of fluorescent proteins to visualize cancer in vivo RM Hoffman Nature Reviews Cancer 5 (10), 796-806, 2005 | 742 | 2005 |
| Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling W Tan, W Zhang, A Strasner, S Grivennikov, JQ Cheng, RM Hoffman, ... Nature 470 (7335), 548-553, 2011 | 737 | 2011 |
| Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases M Yang, E Baranov, P Jiang, FX Sun, XM Li, L Li, S Hasegawa, M Bouvet, ... Proceedings of the National Academy of Sciences 97 (3), 1206-1211, 2000 | 718 | 2000 |
| Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic RM Hoffman Investigational new drugs 17, 343-360, 1999 | 711 | 1999 |
| Biomimetic amplification of nanoparticle homing to tumors D Simberg, T Duza, JH Park, M Essler, J Pilch, L Zhang, AM Derfus, ... Proceedings of the National Academy of Sciences 104 (3), 932-936, 2007 | 628 | 2007 |
| Dissecting p53 tumor suppressor functions in vivo CA Schmitt, JS Fridman, M Yang, E Baranov, RM Hoffman, SW Lowe Cancer cell 1 (3), 289-298, 2002 | 618 | 2002 |
| Transdifferentiation of glioblastoma cells into vascular endothelial cells Y Soda, T Marumoto, D Friedmann-Morvinski, M Soda, F Liu, H Michiue, ... Proceedings of the National Academy of Sciences 108 (11), 4274-4280, 2011 | 615 | 2011 |
| Gene expression profiling predicts clinical outcome of prostate cancer GV Glinsky, AB Glinskii, AJ Stephenson, RM Hoffman, WL Gerald The Journal of clinical investigation 113 (6), 913-923, 2004 | 601 | 2004 |
| Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium M Zhao, M Yang, XM Li, P Jiang, E Baranov, S Li, M Xu, S Penman, ... Proceedings of the National Academy of Sciences 102 (3), 755-760, 2005 | 575 | 2005 |
| Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons Y Amoh, L Li, K Katsuoka, S Penman, RM Hoffman Proceedings of the National Academy of Sciences 102 (15), 5530-5534, 2005 | 542 | 2005 |
| Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata, Y Jiang, ... Cell 155 (2), 384-396, 2013 | 486 | 2013 |
| Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis: a review and synthesis RM Hoffman Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 738 (1-2), 49-87, 1984 | 469 | 1984 |
| Patient-derived orthotopic xenografts: better mimic of metastasis than subcutaneous xenografts RM Hoffman Nature Reviews Cancer 15 (8), 451-452, 2015 | 459 | 2015 |
| A metastatic nude-mouse model of human pancreatic cancer constructed orthotopically with histologically intact patient specimens. X Fu, F Guadagni, RM Hoffman Proceedings of the National Academy of Sciences 89 (12), 5645-5649, 1992 | 453 | 1992 |
| Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. XY Fu, JM Besterman, A Monosov, RM Hoffman Proceedings of the National Academy of Sciences 88 (20), 9345-9349, 1991 | 444 | 1991 |
| Nestin expression in hair follicle sheath progenitor cells L Li, J Mignone, M Yang, M Matic, S Penman, G Enikolopov, RM Hoffman Proceedings of the National Academy of Sciences 100 (17), 9958-9961, 2003 | 426 | 2003 |
| Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1 C Folkins, Y Shaked, S Man, T Tang, CR Lee, Z Zhu, RM Hoffman, ... Cancer research 69 (18), 7243-7251, 2009 | 417 | 2009 |
