Chiral neutral zirconium amidate complexes for the asymmetric hydroamination of alkenes MC Wood, DC Leitch, CS Yeung, JA Kozak, LL Schafer Angewandte Chemie International Edition 46 (3), 354-358, 2007 | 360 | 2007 |
The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ... Organic Process Research & Development 23 (6), 1213-1242, 2019 | 359 | 2019 |
Intramolecular Hydroamination of Unactived Olefins with Ti(NMe2)4 as a Precatalyst JA Bexrud, JD Beard, DC Leitch, LL Schafer Organic Letters 7 (10), 1959-1962, 2005 | 254 | 2005 |
Selective C− H activation α to primary amines. Bridging metallaaziridines for catalytic, intramolecular α-alkylation JA Bexrud, P Eisenberger, DC Leitch, PR Payne, LL Schafer Journal of the American Chemical Society 131 (6), 2116-2118, 2009 | 201 | 2009 |
Broadening the scope of group 4 hydroamination catalysis using a tethered ureate ligand DC Leitch, PR Payne, CR Dunbar, LL Schafer Journal of the American Chemical Society 131 (51), 18246-18247, 2009 | 200 | 2009 |
An Easy‐To‐Use, Regioselective, and Robust Bis (amidate) Titanium Hydroamination Precatalyst: Mechanistic and Synthetic Investigations toward the Preparation of … Z Zhang, DC Leitch, M Lu, BO Patrick, LL Schafer Chemistry–A European Journal 13 (7), 2012-2022, 2007 | 136 | 2007 |
Mechanistic Elucidation of Intramolecular Aminoalkene Hydroamination Catalyzed by a Tethered Bis (ureate) Complex: Evidence for Proton-Assisted C–N Bond Formation at Zirconium DC Leitch, RH Platel, LL Schafer Journal of the American Chemical Society 133 (39), 15453-15463, 2011 | 108 | 2011 |
Bis (amidate) bis (amido) titanium complex: a regioselective intermolecular alkyne hydroamination catalyst JCH Yim, JA Bexrud, RO Ayinla, DC Leitch, LL Schafer The Journal of Organic Chemistry 79 (5), 2015-2028, 2014 | 98 | 2014 |
The power and accessibility of high-throughput methods for catalysis research CL Allen, DC Leitch, MS Anson, MA Zajac Nature Catalysis 2 (1), 2-4, 2019 | 88 | 2019 |
Beyond bioisosteres: divergent synthesis of azabicyclohexanes and cyclobutenyl amines from bicyclobutanes K Dhake, KJ Woelk, J Becica, A Un, SE Jenny, DC Leitch Angewandte Chemie 134 (27), e202204719, 2022 | 77 | 2022 |
Upgrading light hydrocarbons via tandem catalysis: a dual homogeneous Ta/Ir system for alkane/alkene coupling DC Leitch, YC Lam, JA Labinger, JE Bercaw Journal of the American Chemical Society 135 (28), 10302-10305, 2013 | 75 | 2013 |
A palladium-catalysed multicomponent coupling approach to conjugated poly (1, 3-dipoles) and polyheterocycles DC Leitch, LV Kayser, ZY Han, AR Siamaki, EN Keyzer, A Gefen, ... Nature Communications 6 (1), 7411, 2015 | 68 | 2015 |
Isolation of catalytic intermediates in hydroamination reactions: insertion of internal alkynes into a zirconium–amido bond DC Leitch, CS Turner, LL Schafer Angewandte Chemie International Edition 49 (36), 6382-6386, 2010 | 68 | 2010 |
Mechanistic Insight Enables Practical, Scalable, Room Temperature Chan–Lam N-Arylation of N-Aryl Sulfonamides JC Vantourout, L Li, E Bendito-Moll, S Chabbra, K Arrington, BE Bode, ... ACS Catalysis 8 (10), 9560-9566, 2018 | 67 | 2018 |
Development and Cycloaddition Reactivity of a New Class of Pyridine‐Based Mesoionic 1, 3‐Dipole H Erguven, DC Leitch, EN Keyzer, BA Arndtsen Angewandte Chemie 129 (22), 6174-6178, 2017 | 41 | 2017 |
Convergent synthesis of the NS5B inhibitor GSK8175 enabled by transition metal catalysis K Arrington, GA Barcan, NA Calandra, GA Erickson, L Li, L Liu, MG Nilson, ... The Journal of Organic Chemistry 84 (8), 4680-4694, 2018 | 34 | 2018 |
Scope and mechanism of homogeneous tantalum/iridium tandem catalytic alkane/alkene upgrading using sacrificial hydrogen acceptors DC Leitch, JA Labinger, JE Bercaw Organometallics 33 (13), 3353-3365, 2014 | 34 | 2014 |
N, O‐Chelates of Group 4 Metals: Contrasting the Use of Amidates and Ureates in the Synthesis of Metal Dichlorides DC Leitch, JD Beard, RK Thomson, VA Wright, BO Patrick, LL Schafer European Journal of Inorganic Chemistry 2009 (18), 2691-2701, 2009 | 34 | 2009 |
Zirconium Alkyl Complexes Supported by Ureate Ligands: Synthesis, Characterization, and Precursors to Metal− Element Multiple Bonds DC Leitch, LL Schafer Organometallics 29 (21), 5162-5172, 2010 | 31 | 2010 |
Development and scale-up of continuous electrocatalytic hydrogenation of functionalized nitro arenes, nitriles, and unsaturated aldehydes JD Egbert, EC Thomsen, SA O’Neill-Slawecki, DM Mans, DC Leitch, ... Organic Process Research & Development 23 (9), 1803-1812, 2019 | 30 | 2019 |