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Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes A Siepel, G Bejerano, JS Pedersen, AS Hinrichs, M Hou, K Rosenbloom, ... Genome research 15 (8), 1034-1050, 2005 | 4764 | 2005 |
Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution Project management: Fulton Lucinda A. 1 Mardis Elaine R. 1 Wilson Richard K. 1 Nature 432 (7018), 695-716, 2004 | 2926 | 2004 |
Detection of nonneutral substitution rates on mammalian phylogenies KS Pollard, MJ Hubisz, KR Rosenbloom, A Siepel Genome research 20 (1), 110-121, 2010 | 2667 | 2010 |
Evolutionary and biomedical insights from the rhesus macaque genome RA Gibbs, J Rogers, MG Katze, R Bumgarner, GM Weinstock, ER Mardis, ... science 316 (5822), 222-234, 2007 | 1494 | 2007 |
The UCSC genome browser database: update 2006 AS Hinrichs, D Karolchik, R Baertsch, GP Barber, G Bejerano, H Clawson, ... Nucleic acids research 34 (suppl_1), D590-D598, 2006 | 1405 | 2006 |
A high-resolution map of human evolutionary constraint using 29 mammals K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ... Nature 478 (7370), 476-482, 2011 | 1273 | 2011 |
An RNA gene expressed during cortical development evolved rapidly in humans KS Pollard, SR Salama, N Lambert, MA Lambot, S Coppens, JS Pedersen, ... Nature 443 (7108), 167-172, 2006 | 1160 | 2006 |
Comparative analyses of multi-species sequences from targeted genomic regions JW Thomas, JW Touchman, RW Blakesley, GG Bouffard, ... Nature 424 (6950), 788-793, 2003 | 783 | 2003 |
Phylogenetic hidden Markov models R Nielsen, A Siepel, D Haussler Statistical methods in molecular evolution, 325-351, 2005 | 768* | 2005 |
Comparative and demographic analysis of orang-utan genomes DP Locke, LDW Hillier, WC Warren, KC Worley, LV Nazareth, DM Muzny, ... Nature 469 (7331), 529-533, 2011 | 702 | 2011 |
Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers LJ Core, AL Martins, CG Danko, CT Waters, A Siepel, JT Lis Nature genetics 46 (12), 1311-1320, 2014 | 690 | 2014 |
Genome sequencing highlights the dynamic early history of dogs AH Freedman, I Gronau, RM Schweizer, D Ortega-Del Vecchyo, E Han, ... PLoS genetics 10 (1), e1004016, 2014 | 688 | 2014 |
Identification and classification of conserved RNA secondary structures in the human genome JS Pedersen, G Bejerano, A Siepel, K Rosenbloom, K Lindblad-Toh, ... PLoS computational biology 2 (4), e33, 2006 | 662 | 2006 |
Bayesian inference of ancient human demography from individual genome sequences I Gronau, MJ Hubisz, B Gulko, CG Danko, A Siepel Nature genetics 43 (10), 1031-1034, 2011 | 656 | 2011 |
Patterns of positive selection in six mammalian genomes C Kosiol, T Vinař, RR da Fonseca, MJ Hubisz, CD Bustamante, R Nielsen, ... PLoS genetics 4 (8), e1000144, 2008 | 626 | 2008 |
A distal enhancer and an ultraconserved exon are derived from a novel retroposon G Bejerano, CB Lowe, N Ahituv, B King, A Siepel, SR Salama, EM Rubin, ... Nature 441 (7089), 87-90, 2006 | 580 | 2006 |
Forces shaping the fastest evolving regions in the human genome KS Pollard, SR Salama, B King, AD Kern, T Dreszer, S Katzman, A Siepel, ... PLoS genetics 2 (10), e168, 2006 | 561 | 2006 |
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells N Hah, CG Danko, L Core, JJ Waterfall, A Siepel, JT Lis, WL Kraus Cell 145 (4), 622-634, 2011 | 548 | 2011 |
Ancient gene flow from early modern humans into Eastern Neanderthals M Kuhlwilm, I Gronau, MJ Hubisz, C De Filippo, J Prado-Martinez, ... Nature 530 (7591), 429-433, 2016 | 541 | 2016 |