Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix LK Jennings, KM Storek, HE Ledvina, C Coulon, LS Marmont, ... Proceedings of the National Academy of Sciences 112 (36), 11353-11358, 2015 | 645 | 2015 |
An interbacterial NAD (P)+ glycohydrolase toxin requires elongation factor Tu for delivery to target cells JC Whitney, D Quentin, S Sawai, M LeRoux, BN Harding, HE Ledvina, ... Cell 163 (3), 607-619, 2015 | 222 | 2015 |
Cyclic di‐AMP targets the cystathionine beta‐synthase domain of the osmolyte transporter OpuC TAN Huynh, PH Choi, K Sureka, HE Ledvina, J Campillo, L Tong, ... Molecular microbiology 102 (2), 233-243, 2016 | 107 | 2016 |
Secreted effectors encoded within and outside of the Francisella pathogenicity island promote intramacrophage growth A Eshraghi, J Kim, AC Walls, HE Ledvina, CN Miller, KM Ramsey, ... Cell host & microbe 20 (5), 573-583, 2016 | 80 | 2016 |
A phosphatidylinositol 3-kinase effector alters phagosomal maturation to promote intracellular growth of Francisella HE Ledvina, KA Kelly, A Eshraghi, RL Plemel, SB Peterson, B Lee, ... Cell host & microbe 24 (2), 285-295. e8, 2018 | 63 | 2018 |
An E1–E2 fusion protein primes antiviral immune signalling in bacteria HE Ledvina, Q Ye, Y Gu, AE Sullivan, Y Quan, RK Lau, H Zhou, ... Nature 616 (7956), 319-325, 2023 | 45 | 2023 |
An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations MH de Moraes, FS Hsu, D Huang, DE Bosch, J Zeng, MC Radey, ... Elife 10, e62967, 2021 | 38 | 2021 |
Depletion of alveolar macrophages in CD11c diphtheria toxin receptor mice produces an inflammatory response LM Roberts, HE Ledvina, S Tuladhar, D Rana, SP Steele, GD Sempowski, ... Immunity, Inflammation and Disease 3 (2), 71-81, 2015 | 23 | 2015 |
Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in Francisella tularensis KM Ramsey, HE Ledvina, TM Tresko, JM Wandzilak, CA Tower, T Tallo, ... PLoS pathogens 16 (6), e1008566, 2020 | 21 | 2020 |
The secreted effector protein EspZ is essential for virulence of rabbit enteropathogenic Escherichia coli JS Wilbur, W Byrd, S Ramamurthy, HE Ledvina, K Khirfan, MW Riggs, ... Infection and immunity 83 (3), 1139-1149, 2015 | 15 | 2015 |
Distinct innate responses are induced by attenuated Salmonella enterica serovar Typhimurium mutants DA Powell, LM Roberts, HE Ledvina, GD Sempowski, R Curtiss III, ... Cellular immunology 299, 42-49, 2016 | 14 | 2016 |
cGASylation by a bacterial E1-E2 fusion protein primes antiviral immune signaling HE Ledvina, Q Ye, Y Gu, Y Quan, RK Lau, H Zhou, KD Corbett, ... BioRxiv, 2022.03. 31.486616, 2022 | 11 | 2022 |
TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpB LM Roberts, HE Ledvina, GD Sempowski, JA Frelinger Frontiers in immunology 5, 426, 2014 | 9 | 2014 |
Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism SY Ting, KD LaCourse, HE Ledvina, R Zhang, MC Radey, HD Kulasekara, ... Elife 11, e74658, 2022 | 7 | 2022 |
Conservation and similarity of bacterial and eukaryotic innate immunity HE Ledvina, AT Whiteley Nature Reviews Microbiology, 1-15, 2024 | 5 | 2024 |
Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species Y Wang, HE Ledvina, CA Tower, S Kambarev, E Liu, JC Charity, ... Cell Host & Microbe 31 (8), 1359-1370. e7, 2023 | 5 | 2023 |
818 Tseng BS, Scian M, Filloux A, Wozniak DJ, Howell PL, Parsek MR. 2015. Pel is a 819 cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas 820 … LK Jennings, KM Storek, HE Ledvina, C Coulon, LS Marmont, ... Proceedings of the National Academy of Sciences of the 821 United States of …, 0 | 4 | |
Bacterial antiviral defense pathways encode eukaryotic-like ubiquitination systems LR Chambers, Q Ye, J Cai, M Gong, HE Ledvina, H Zhou, AT Whiteley, ... bioRxiv, 2023 | 2 | 2023 |
A eukaryotic-like ubiquitination system in bacterial antiviral defence LR Chambers, Q Ye, J Cai, M Gong, HE Ledvina, H Zhou, AT Whiteley, ... Nature, 1-7, 2024 | 1 | 2024 |
Coordinately regulated interbacterial antagonism defense pathways constitute a bacterial innate immune system SY Ting, KD LaCourse, HE Ledvina, R Zhang, MC Radey, HD Kulasekara, ... bioRxiv, 2021.08. 22.457286, 2021 | 1 | 2021 |