MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function BH Miller, Z Zeier, L Xi, TA Lanz, S Deng, J Strathmann, D Willoughby, ... Proceedings of the National Academy of Sciences 109 (8), 3125-3130, 2012 | 370 | 2012 |
Regulation of the apolipoprotein gene cluster by a long noncoding RNA P Halley, BM Kadakkuzha, MA Faghihi, M Magistri, Z Zeier, O Khorkova, ... Cell reports 6 (1), 222-230, 2014 | 222 | 2014 |
Clinical implementation of pharmacogenetic decision support tools for antidepressant drug prescribing Z Zeier, LL Carpenter, NH Kalin, CI Rodriguez, WM McDonald, AS Widge, ... American Journal of Psychiatry 175 (9), 873-886, 2018 | 148 | 2018 |
Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome Z Zeier, A Kumar, K Bodhinathan, JA Feller, TC Foster, DC Bloom Gene therapy 16 (9), 1122-1129, 2009 | 81 | 2009 |
Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD NS Andrade, M Ramic, R Esanov, W Liu, MJ Rybin, G Gaidosh, ... Molecular neurodegeneration 15, 1-18, 2020 | 73 | 2020 |
Gene expression in the hippocampus: regionally specific effects of aging and caloric restriction Z Zeier, I Madorsky, Y Xu, WO Ogle, L Notterpek, TC Foster Mechanisms of ageing and development 132 (1-2), 8-19, 2011 | 73 | 2011 |
Organoid models of glioblastoma and their role in drug discovery MJ Rybin, ME Ivan, NG Ayad, Z Zeier Frontiers in cellular neuroscience 15, 605255, 2021 | 59 | 2021 |
Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins GC Sartor, AM Malvezzi, A Kumar, NS Andrade, HJ Wiedner, SJ Vilca, ... Journal of Neuroscience 39 (4), 612-626, 2019 | 58 | 2019 |
CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro KE Meijboom, A Abdallah, NP Fordham, H Nagase, T Rodriguez, C Kraus, ... Nature communications 13 (1), 6286, 2022 | 51 | 2022 |
The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans VJ Peschansky, C Pastori, Z Zeier, K Wentzel, D Velmeshev, M Magistri, ... Molecular and Cellular Neuroscience 74, 49-57, 2016 | 43 | 2016 |
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells R Esanov, KC Belle, M van Blitterswijk, VV Belzil, R Rademakers, ... Experimental neurology 277, 171-177, 2016 | 40 | 2016 |
Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways AL Johnstone, NS Andrade, E Barbier, BB Khomtchouk, CA Rienas, ... Addiction biology 26 (1), e12816, 2021 | 39 | 2021 |
Bromodomain inhibitors regulate the C9ORF72 locus in ALS Z Zeier, R Esanov, KC Belle, CH Volmar, AL Johnstone, P Halley, ... Experimental neurology 271, 241-250, 2015 | 39 | 2015 |
A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD R Esanov, GT Cabrera, NS Andrade, TF Gendron, RH Brown, M Benatar, ... Molecular neurodegeneration 12, 1-11, 2017 | 35 | 2017 |
The FMR1 promoter is selectively hydroxymethylated in primary neurons of fragile X syndrome patients R Esanov, NS Andrade, S Bennison, C Wahlestedt, Z Zeier Human molecular genetics 25 (22), 4870-4880, 2016 | 29 | 2016 |
Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells VJ Peschansky, C Pastori, Z Zeier, D Motti, K Wentzel, D Velmeshev, ... Frontiers in genetics 6, 263, 2015 | 29 | 2015 |
Single-cell multi-cohort dissection of the schizophrenia transcriptome WB Ruzicka, S Mohammadi, JF Fullard, J Davila-Velderrain, S Subburaju, ... Science 384 (6698), eadg5136, 2024 | 25 | 2024 |
The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion AM Jermakowicz, MJ Rybin, RK Suter, JN Sarkaria, Z Zeier, Y Feng, ... Scientific reports 11 (1), 23370, 2021 | 23 | 2021 |
EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia AL Johnstone, JJ O'Reilly, AJ Patel, Z Guo, NS Andrade, M Magistri, ... Neurobiology of disease 119, 149-158, 2018 | 19 | 2018 |
Long non-coding RNA-targeting therapeutics: discovery and development update O Khorkova, J Stahl, A Joji, CH Volmar, Z Zeier, C Wahlestedt Expert opinion on drug discovery 18 (9), 1011-1029, 2023 | 13 | 2023 |