Structural basis of TIR-domain-assembly formation in MAL-and MyD88-dependent TLR4 signaling T Ve, PR Vajjhala, A Hedger, T Croll, F DiMaio, S Horsefield, X Yu, ... Nature structural & molecular biology 24 (9), 743-751, 2017 | 164 | 2017 |
Viral M45 and necroptosis‐associated proteins form heteromeric amyloid assemblies CLL Pham, N Shanmugam, M Strange, A O'Carroll, JWP Brown, ... EMBO reports 20 (2), e46518, 2019 | 87 | 2019 |
Cell-free formation and interactome analysis of caveolae WR Jung, E Sierecki, M Bastiani, A O’Carroll, K Alexandrov, J Rae, ... The Journal of cell biology 217 (6), 2141, 2018 | 51 | 2018 |
Single-molecule fluorescence reveals the oligomerization and folding steps driving the prion-like behavior of ASC Y Gambin, N Giles, A O'Carroll, M Polinkovsky, D Hunter, E Sierecki Journal of molecular biology 430 (4), 491-508, 2018 | 38 | 2018 |
Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88 A O’Carroll, B Chauvin, JWP Brown, A Meagher, J Coyle, J Schill, ... BMC biology 16, 1-16, 2018 | 28 | 2018 |
Prions and Prion-like assemblies in neurodegeneration and immunity: The emergence of universal mechanisms across health and disease A O’Carroll, J Coyle, Y Gambin Seminars in Cell & Developmental Biology 99, 115-130, 2020 | 26 | 2020 |
Corrigendum to" Single-Molecule Fluorescence Reveals the Oligomerisation and Folding Steps Driving the Prion-like Behaviour of ASC"[J. Mol. Biol. 430 (4)(February 16, 2018) 491 … Y Gambin, N Giles, A O'Carroll, ME Polinkovsky, DJB Hunter, E Sierecki Journal of molecular biology 430 (8), 1263, 2018 | 1 | 2018 |
Prion‐like protein polymerisation underlies signal transduction in innate immunity: The emergence of a universal mechanism? A O'Carroll, T Ve, M Moustaqil, N Giles, A Bhumkar, D Hunter, B Kobe, ... The FASEB Journal 31, 937.1-937.1, 2017 | 1 | 2017 |
Competing Interactions between Viral RHIM Amyloid-forming Proteins and Host Functional Amyloid Structures Modulate the Cellular Response to Infection M Sunde, CLL Pham, N Shanmugam, MODG Baker, M Steain, A O'Carroll, ... Biophysical Journal 118 (3), 180a-181a, 2020 | | 2020 |
Enteropathogenic E. coli Hijacks Programmed Host‐Cell Death Pathways by Interfering with the Higher Order Oligomerization of Immune System Proteins A Monserrat‐Martinez, G Redpath, MA Govendir, A O'Carroll, ... The FASEB Journal 33 (S1), 649.6-649.6, 2019 | | 2019 |
Effects of Pathological Mutations on the Prion-Like Polymerisation of MyD88 A O’Carroll, B Chauvin, J Brown, A Meagher, J Coyle, D Hunter, ... bioRxiv, 351726, 2018 | | 2018 |
The RHIM within the M45 protein from murine cytomegalovirus forms heteromeric functional amyloid fibrils with RIPK1 and RIPK3 CLL Pham, M Strange, A O’Carroll, N Shanmugam, E Sierecki, Y Gambin, ... bioRxiv, 324590, 2018 | | 2018 |
The RHIM within the M45 protein from murine cytomegalovirus forms heteromeric amyloid fibrils with RIPK1 and RIPK3 CLL Pham, M Strange, A O’Carroll, N Shanmugam, E Sierecki, Y Gambin, ... | | 2018 |
Prion‐like protein polymerisation underlies signal transduction in innate immunity: the emergence of a universal mechanism? A O'Carroll, T Ve, D Lau, N Giles, M Moustaqil, A Bhumkar, D Hunter, ... The FASEB Journal 30, 814.3-814.3, 2016 | | 2016 |