High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy*, VS Vykunta*, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature Biotechnology, 1-11, 2022 | 108* | 2022 |
NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting C Tan*, R Hiwa*, JL Mueller, V Vykunta, K Hibiya, M Noviski, J Huizar, ... Nature immunology 21 (10), 1267-1279, 2020 | 62 | 2020 |
CRISPR–Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells E Lin-Shiao*, WG Pfeifer*, BR Shy, M Saffari Doost, E Chen, VS Vykunta, ... Nucleic acids research 50 (3), 1256-1268, 2022 | 50 | 2022 |
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies DB Goodman*, CS Azimi*, K Kearns, A Talbot, K Garakani, J Garcia, ... Science Translational Medicine 14 (670), eabm1463, 2022 | 39 | 2022 |
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes DV Foss*, JJ Muldoon*, DN Nguyen*, D Carr, SU Sahu, JM Hunsinger, ... Nature Biomedical Engineering, 1-14, 2023 | 38 | 2023 |
Optimal development of mature B cells requires recognition of endogenous antigens M Noviski, C Tan, J Huizar, V Vykunta, JL Mueller, J Zikherman The Journal of Immunology 203 (2), 418-428, 2019 | 22 | 2019 |
Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses JF Brooks, C Tan, JL Mueller, K Hibiya, R Hiwa, V Vykunta, J Zikherman Cell reports 36 (9), 2021 | 17 | 2021 |
Molecular basis for potent B cell responses to antigen displayed on particles of viral size JF Brooks*, J Riggs*, JL Mueller, R Mathenge, WY Wholey, AR Meyer, ... Nature Immunology, 1-16, 2023 | 15 | 2023 |
Mast cells help organize the Peyer’s patch niche for induction of IgA responses M De Giovanni, VS Vykunta, A Biram, KY Chen, H Taglinao, J An, ... Science Immunology 9 (93), eadj7363, 2024 | 2 | 2024 |
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection CR Chang, VS Vykunta, DB Goodman, JJ Muldoon, WA Nyberg, C Liu, ... bioRxiv, 2024 | 1 | 2024 |
Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling J Lee, ME Robinson, R Sun, K Kume, N Ma, KN Cosgun, LN Chan, ... bioRxiv, 2023.03. 13.532151, 2023 | 1 | 2023 |
Altered cancer metabolism and implications for next-generation CAR T-cell therapies R Ramapriyan*, VS Vykunta*, G Vandecandelaere, LGK Richardson, ... Pharmacology & Therapeutics, 108667, 2024 | | 2024 |
CD25 recruits inhibitory phosphatases for feedback control of B-cell receptor signaling R Sun, J Lee, ME Robinson, K Kume, KN Cosgun, LN Chan, E Leveille, ... The Journal of Immunology 210 (1_Supplement), 154.23-154.23, 2023 | | 2023 |
Compositions and methods for modifying a target nucleic acid A Marson, B Shy, J Eyquem, V Vykunta US Patent App. 17/911,387, 2023 | | 2023 |
CD25 As Feedback Regulator of Oncogenic TCR Signaling in T-Cell Lymphoma R Sun, J Lee, T Wartewig, ME Robinson, A Bigogno, D Fonseca Arce, ... Blood 140 (Supplement 1), 5975-5976, 2022 | | 2022 |
A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling J Lee, K Kume, ME Robinson, R Sun, N Ma, Z Chen, G Xiao, KN Cosgun, ... Blood 140 (Supplement 1), 1698-1699, 2022 | | 2022 |