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Andrew C Giles
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High-throughput behavioral analysis in C. elegans
NA Swierczek, AC Giles, CH Rankin, RA Kerr
Nature methods 8 (7), 592-598, 2011
4712011
Dopamine mediates context-dependent modulation of sensory plasticity in C. elegans
KS Kindt, KB Quast, AC Giles, S De, D Hendrey, I Nicastro, CH Rankin, ...
Neuron 55 (4), 662-676, 2007
2102007
Behavioral and genetic characterization of habituation using Caenorhabditis elegans
AC Giles, CH Rankin
Neurobiology of learning and memory 92 (2), 139-146, 2009
1242009
Genetic behavioral screen identifies an orphan anti-opioid system
D Wang, HM Stoveken, S Zucca, M Dao, C Orlandi, C Song, I Masuho, ...
Science 365 (6459), 1267-1273, 2019
512019
Dopamine receptor DOP-4 modulates habituation to repetitive photoactivation of a C. elegans polymodal nociceptor
EL Ardiel, AC Giles, JY Alex, TH Lindsay, SR Lockery, CH Rankin
Learning & Memory 23 (10), 495-503, 2016
482016
Investigations of learning and memory in Caenorhabditis elegans
AC Giles, JK Rose, CH Rankin
International review of neurobiology 69, 37-71, 2005
482005
Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease
AC Giles, B Grill
Neural Development 15, 1-18, 2020
452020
Habituation as an adaptive shift in response strategy mediated by neuropeptides
EL Ardiel, AJ Yu, AC Giles, CH Rankin
npj Science of Learning 2 (1), 9, 2017
432017
Context-dependent operation of neural circuits underlies a navigation behavior in Caenorhabditis elegans
M Ikeda, S Nakano, AC Giles, L Xu, WS Costa, A Gottschalk, I Mori
Proceedings of the National Academy of Sciences 117 (11), 6178-6188, 2020
412020
A complex containing the O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 regulates GABA neuron function
AC Giles, M Desbois, KJ Opperman, R Tavora, MJ Maroni, B Grill
Journal of Biological Chemistry 294 (17), 6843-6856, 2019
372019
The HECT family ubiquitin ligase EEL-1 regulates neuronal function and development
KJ Opperman, B Mulcahy, AC Giles, MG Risley, RL Birnbaum, ED Tulgren, ...
Cell reports 19 (4), 822-835, 2017
372017
Intensity discrimination deficits cause habituation changes in middle-aged Caenorhabditis elegans
TA Timbers, AC Giles, EL Ardiel, RA Kerr, CH Rankin
Neurobiology of aging 34 (2), 621-631, 2013
372013
Autophagy is inhibited by ubiquitin ligase activity in the nervous system
O Crawley, KJ Opperman, M Desbois, I Adrados, MA Borgen, AC Giles, ...
Nature communications 10 (1), 5017, 2019
362019
A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease
K Ikenaka, Y Tsukada, AC Giles, T Arai, Y Nakadera, S Nakano, K Kawai, ...
Scientific reports 9 (1), 10104, 2019
352019
Neonatal ventral hippocampal lesions in male and female rats: effects on water maze, locomotor activity, plus-maze and prefrontal cortical GABA and glutamate release in adulthood
RJ Beninger, KJ Tuerke, JK Forsyth, A Giles, L Xue, RJ Boegman, ...
Behavioural brain research 202 (2), 198-209, 2009
332009
Nucleus accumbens PKA inhibition blocks acquisition but enhances expression of amphetamine-produced conditioned activity in rats
TV Gerdjikov, AC Giles, SN Swain, RJ Beninger
Psychopharmacology 190, 65-72, 2007
252007
Genetic modeling of GNAO1 disorder delineates mechanisms of Gαo dysfunction
D Wang, M Dao, BS Muntean, AC Giles, KA Martemyanov, B Grill
Human Molecular Genetics 31 (4), 510-522, 2022
222022
A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning
O Crawley, AC Giles, M Desbois, S Kashyap, R Birnbaum, B Grill
PLoS genetics 13 (12), e1007095, 2017
222017
Developmental function of the PHR protein RPM-1 is required for learning in Caenorhabditis elegans
AC Giles, KJ Opperman, CH Rankin, B Grill
G3: Genes, Genomes, Genetics 5 (12), 2745-2757, 2015
182015
Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects
L AlAbdi, M Desbois, DV Rusnac, RA Sulaiman, JA Rosenfeld, S Lalani, ...
Brain 146 (4), 1373-1387, 2023
152023
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