| Generation of high-affinity DNA aptamers using an expanded genetic alphabet M Kimoto, R Yamashige, K Matsunaga, S Yokoyama, I Hirao Nature biotechnology 31 (5), 453-457, 2013 | 541 | 2013 |
| An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA I Hirao, M Kimoto, T Mitsui, T Fujiwara, R Kawai, A Sato, Y Harada, ... Nature Methods 3 (9), 729-735, 2006 | 299 | 2006 |
| An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules M Kimoto, R Kawai, T Mitsui, S Yokoyama, I Hirao Nucleic acids research 37 (2), e14-e14, 2009 | 218 | 2009 |
| Highly specific unnatural base pair systems as a third base pair for PCR amplification R Yamashige, M Kimoto, Y Takezawa, A Sato, T Mitsui, S Yokoyama, ... Nucleic acids research 40 (6), 2793-2806, 2012 | 184 | 2012 |
| Natural versus artificial creation of base pairs in DNA: origin of nucleobases from the perspectives of unnatural base pair studies I Hirao, M Kimoto, R Yamashige Accounts of chemical research 45 (12), 2055-2065, 2012 | 181 | 2012 |
| A two-unnatural-base-pair system toward the expansion of the genetic code I Hirao, Y Harada, M Kimoto, T Mitsui, T Fujiwara, S Yokoyama Journal of the American Chemical Society 126 (41), 13298-13305, 2004 | 141 | 2004 |
| An unnatural hydrophobic base pair with shape complementarity between pyrrole-2-carbaldehyde and 9-methylimidazo [(4, 5)-b] pyridine T Mitsui, A Kitamura, M Kimoto, T To, A Sato, I Hirao, S Yokoyama Journal of the American Chemical Society 125 (18), 5298-5307, 2003 | 137 | 2003 |
| High-affinity DNA aptamer generation targeting von Willebrand factor A1-domain by genetic alphabet expansion for systematic evolution of ligands by exponential enrichment using … K Matsunaga, M Kimoto, I Hirao Journal of the American Chemical Society 139 (1), 324-334, 2017 | 134 | 2017 |
| An efficient unnatural base pair for PCR amplification I Hirao, T Mitsui, M Kimoto, S Yokoyama Journal of the American Chemical Society 129 (50), 15549-15555, 2007 | 134 | 2007 |
| Unnatural base pairs for specific transcription T Ohtsuki, M Kimoto, M Ishikawa, T Mitsui, I Hirao, S Yokoyama Proceedings of the National Academy of Sciences 98 (9), 4922-4925, 2001 | 132 | 2001 |
| Site-specific fluorescent labeling of RNA molecules by specific transcription using unnatural base pairs R Kawai, M Kimoto, S Ikeda, T Mitsui, M Endo, S Yokoyama, I Hirao Journal of the American Chemical Society 127 (49), 17286-17295, 2005 | 127 | 2005 |
| Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma I Hirao, M Kimoto Proceedings of the Japan Academy, Series B 88 (7), 345-367, 2012 | 95 | 2012 |
| Genetic alphabet expansion technology by creating unnatural base pairs M Kimoto, I Hirao Chemical Society Reviews 49 (21), 7602-7626, 2020 | 94 | 2020 |
| Site-specific biotinylation of RNA molecules by transcription using unnatural base pairs K Moriyama, M Kimoto, T Mitsui, S Yokoyama, I Hirao Nucleic acids research 33 (15), e129-e129, 2005 | 93 | 2005 |
| A unique fluorescent base analogue for the expansion of the genetic alphabet M Kimoto, T Mitsui, S Yokoyama, I Hirao Journal of the American Chemical Society 132 (14), 4988-4989, 2010 | 92 | 2010 |
| Fluorescent probing for RNA molecules by an unnatural base-pair system M Kimoto, T Mitsui, Y Harada, A Sato, S Yokoyama, I Hirao Nucleic acids research 35 (16), 5360-5369, 2007 | 85 | 2007 |
| Synthesis of 6-(2-thienyl) purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides T Fujiwara, M Kimoto, H Sugiyama, I Hirao, S Yokoyama Bioorganic & medicinal chemistry letters 11 (16), 2221-2223, 2001 | 85 | 2001 |
| Anti‐(Raf‐1) RNA aptamers that inhibit Ras‐induced Raf‐1 activation M Kimoto, M Shirouzu, S Mizutani, H Koide, Y Kaziro, I Hirao, ... European journal of biochemistry 269 (2), 697-704, 2002 | 74 | 2002 |
| Site-specific incorporation of a photo-crosslinking component into RNA by T7 transcription mediated by unnatural base pairs M Kimoto, M Endo, T Mitsui, T Okuni, I Hirao, S Yokoyama Chemistry & biology 11 (1), 47-55, 2004 | 73 | 2004 |
| Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF165 toward pharmaceutical applications M Kimoto, M Nakamura, I Hirao Nucleic acids research 44 (15), 7487-7494, 2016 | 70 | 2016 |
Masayuki EndoKyoto University在 kansai-u.ac.jp 的电子邮件经过验证
