Maternal nutrition at conception modulates DNA methylation of human metastable epialleles P Dominguez-Salas, SE Moore, MS Baker, AW Bergen, SE Cox, RA Dyer, ... Nature communications 5 (1), 3746, 2014 | 577 | 2014 |
Bayesian variable selection regression for genome-wide association studies and other large-scale problems Y Guan, M Stephens | 461 | 2011 |
Long-read sequencing and de novo assembly of a Chinese genome L Shi, Y Guo, C Dong, J Huddleston, H Yang, X Han, A Fu, Q Li, N Li, ... Nature communications 7 (1), 12065, 2016 | 293 | 2016 |
Practical issues in imputation-based association mapping Y Guan, M Stephens PLoS genetics 4 (12), e1000279, 2008 | 226 | 2008 |
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1α are associated with C-reactive protein AP Reiner, MJ Barber, Y Guan, PM Ridker, LA Lange, DI Chasman, ... The American Journal of Human Genetics 82 (5), 1193-1201, 2008 | 221 | 2008 |
Detecting structure of haplotypes and local ancestry Y Guan Genetics 196 (3), 625-642, 2014 | 209 | 2014 |
Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome DH Yu, M Gadkari, Q Zhou, S Yu, N Gao, Y Guan, D Schady, TN Roshan, ... Genome biology 16, 1-16, 2015 | 146 | 2015 |
MVP predicts the pathogenicity of missense variants by deep learning H Qi, H Zhang, Y Zhao, C Chen, JJ Long, WK Chung, Y Guan, Y Shen Nature communications 12 (1), 510, 2021 | 142 | 2021 |
Variation in human recombination rates and its genetic determinants A Fledel-Alon, EM Leffler, Y Guan, M Stephens, G Coop, M Przeworski PloS one 6 (6), e20321, 2011 | 126 | 2011 |
Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice DH Yu, RA Waterland, P Zhang, D Schady, MH Chen, Y Guan, M Gadkari, ... The Journal of clinical investigation 124 (9), 3708-3712, 2014 | 103 | 2014 |
Strong selection at MHC in Mexicans since admixture Q Zhou, L Zhao, Y Guan PLoS genetics 12 (2), e1005847, 2016 | 62 | 2016 |
Small-world MCMC and convergence to multi-modal distributions: From slow mixing to fast mixing Y Guan, SM Krone | 45 | 2007 |
Markov chain Monte Carlo in small worlds Y Guan, R Fleißner, P Joyce, SM Krone Statistics and computing 16, 193-202, 2006 | 44 | 2006 |
Detecting local haplotype sharing and haplotype association H Xu, Y Guan Genetics 197 (3), 823-838, 2014 | 37 | 2014 |
Edematous severe acute malnutrition is characterized by hypomethylation of DNA KV Schulze, S Swaminathan, S Howell, A Jajoo, NC Lie, O Brown, ... Nature communications 10 (1), 5791, 2019 | 32 | 2019 |
On the null distribution of Bayes factors in linear regression Q Zhou, Y Guan Journal of the American Statistical Association 113 (523), 1362-1371, 2018 | 26 | 2018 |
A locus on chromosome 5 shows African ancestry–limited association with alloimmunization in sickle cell disease LM Williams, Z Qi, K Batai, S Hooker, NJ Hall, RF Machado, A Chen, ... Blood advances 2 (24), 3637-3647, 2018 | 23 | 2018 |
Informative priors on fetal fraction increase power of the noninvasive prenatal screen H Xu, S Wang, LL Ma, S Huang, L Liang, Q Liu, YY Liu, KD Liu, ZM Tan, ... Genetics in Medicine 20 (8), 817-824, 2018 | 21 | 2018 |
Fast model-fitting of Bayesian variable selection regression using the iterative complex factorization algorithm Q Zhou, Y Guan Bayesian analysis 14 (2), 573, 2018 | 17 | 2018 |
Correlation of serum MMP3 and other biomarkers with clinical outcomes in patients with ankylosing spondylitis: a pilot study D He, Q Zhu, Q Zhou, Q Qi, H Sun, LM Zachariah, G Wang, JD Reveille, ... Clinical rheumatology 36, 1819-1826, 2017 | 14 | 2017 |