Proteomics approaches for biomarker and drug target discovery in ALS and FTD TJ Hedl, R San Gil, F Cheng, SL Rayner, JM Davidson, A De Luca, ... Frontiers in Neuroscience 13, 548, 2019 | 82 | 2019 |
p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death AD Foster, LL Flynn, C Cluning, F Cheng, JM Davidson, A Lee, N Polain, ... Scientific reports 11 (1), 11474, 2021 | 25 | 2021 |
ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ SL Rayner, F Cheng, AL Hogan, N Grima, S Yang, YD Ke, CG Au, ... Human Molecular Genetics 30 (11), 971-984, 2021 | 20 | 2021 |
Expanding the family of extracellular chaperones: Identification of human plasma proteins with chaperone activity NJ Geraghty, S Satapathy, M Kelly, F Cheng, A Lee, MR Wilson Protein Science 30 (11), 2272-2286, 2021 | 15 | 2021 |
Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis … F Cheng, A De Luca, AL Hogan, SL Rayner, JM Davidson, M Watchon, ... Frontiers in Molecular Neuroscience 14, 627740, 2021 | 15 | 2021 |
TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex SL Rayner, S Yang, NE Farrawell, CJ Jagaraj, F Cheng, JM Davidson, ... Neurobiology of disease 167, 105673, 2022 | 12 | 2022 |
Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD SL Rayner, A Hogan, JM Davidson, F Cheng, L Luu, M Morsch, I Blair, ... The Neuroscientist 30 (2), 214-228, 2024 | 4 | 2024 |
The E3 ubiquitin ligase SCF cyclin F promotes sequestosome-1/p62 insolubility and foci formation and is dysregulated in ALS and FTD pathogenesis JM Davidson, SSL Wu, SL Rayner, F Cheng, K Duncan, C Russo, ... Molecular Neurobiology 60 (9), 5034-5054, 2023 | 4 | 2023 |
Inter-Regional Proteomic Profiling of the Human Brain Using an Optimized Protein Extraction Method from Formalin-Fixed Tissue to Identify Signaling Pathways JM Davidson, SL Rayner, S Liu, F Cheng, A Di Ieva, RS Chung, A Lee International Journal of Molecular Sciences 24 (5), 4283, 2023 | 2 | 2023 |
PeptideWitch–A software package to produce high-stringency proteomics data visualizations from label-free shotgun proteomics data DCL Handler, F Cheng, AM Shathili, PA Haynes Proteomes 8 (3), 21, 2020 | 2 | 2020 |
Identification of phosphorylated tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal … RAW Radford, SL Rayner, P Szwaja, M Morsch, F Cheng, T Zhu, ... Journal of Neurochemistry 165 (4), 563-586, 2023 | 1 | 2023 |
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3 M Watchon, KJ Robinson, L Luu, Y An, KC Yuan, SK Plenderleith, ... bioRxiv, 2021.04. 30.442119, 2021 | 1 | 2021 |
Treatment with sodium butyrate has therapeutic benefits for Machado-Joseph disease through the induction of autophagy M Watchon, KJ Robinson, L Luu, KC Yuan, A Lee, F Cheng, EK Don, ... bioRxiv., 2021 | 1 | 2021 |
Cyclin F can alter the turnover of TDP-43 SL Rayner, A Hogan, JM Davidson, T Chapman, F Cheng, L Luu, S Wu, ... Neurobiology of Disease 192, 106421, 2024 | | 2024 |
Understanding age-related pathologic changes in TDP-43 functions and their consequence on RNA splicing and signalling in health and disease F Cheng, T Chapman, S Zhang, M Morsch, R Chung, A Lee, SL Rayner Ageing Research Reviews, 102246, 2024 | | 2024 |
Edited by: Mark Oliver Collins, The University of Sheffield, United Kingdom Reviewed by AL Nishimura, ST Weintraub, A Lee, F Cheng, A De Luca, AL Hogan, ... Neuroproteomics: Insight into Brain Function and Disease, 2022 | | 2022 |
BioID analysis of the cyclin F interactome reveals that ALS-variant cyclin F alters the homeostasis of paraspeckle-associated proteins SL Rayner, F Cheng, S Yang, N Grima, YD Ke, CG Au, M Morsch, ... bioRxiv, 2020.04. 30.071365, 2020 | | 2020 |