Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers E Lim, F Vaillant, D Wu, NC Forrest, B Pal, AH Hart, ML Asselin-Labat, ... Nature medicine 15 (8), 907-913, 2009 | 1633 | 2009 |
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway X Chen, D Iliopoulos, Q Zhang, Q Tang, MB Greenblatt, M Hatziapostolou, ... Nature 508 (7494), 103-107, 2014 | 842 | 2014 |
EMT, cell plasticity and metastasis CL Chaffer, BP San Juan, E Lim, RA Weinberg Cancer and Metastasis Reviews 35, 645-654, 2016 | 839 | 2016 |
A single-cell and spatially resolved atlas of human breast cancers SZ Wu, G Al-Eryani, DL Roden, S Junankar, K Harvey, A Andersson, ... Nature genetics 53 (9), 1334-1347, 2021 | 660 | 2021 |
ROAST: rotation gene set tests for complex microarray experiments D Wu, E Lim, F Vaillant, ML Asselin-Labat, JE Visvader, GK Smyth Bioinformatics 26 (17), 2176-2182, 2010 | 576 | 2010 |
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways E Lim, D Wu, B Pal, T Bouras, ML Asselin-Labat, F Vaillant, H Yagita, ... Breast Cancer Research 12, 1-14, 2010 | 477 | 2010 |
Targeting androgen receptor in estrogen receptor-negative breast cancer M Ni, Y Chen, E Lim, H Wimberly, ST Bailey, Y Imai, DL Rimm, XS Liu, ... Cancer cell 20 (1), 119-131, 2011 | 437 | 2011 |
CDK7-dependent transcriptional addiction in triple-negative breast cancer Y Wang, T Zhang, N Kwiatkowski, BJ Abraham, TI Lee, S Xie, H Yuzugullu, ... Cell 163 (1), 174-186, 2015 | 432 | 2015 |
Clinical overview of MDM2/X-targeted therapies A Burgess, KM Chia, S Haupt, D Thomas, Y Haupt, E Lim Frontiers in oncology 6, 7, 2016 | 378 | 2016 |
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ... Nature communications 9 (1), 2897, 2018 | 371 | 2018 |
Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ... Cancer cell 24 (3), 347-364, 2013 | 354 | 2013 |
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study N Harbeck, P Rastogi, M Martin, SM Tolaney, ZM Shao, PA Fasching, ... Annals of Oncology 32 (12), 1571-1581, 2021 | 316 | 2021 |
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ... The EMBO journal 39 (19), e104063, 2020 | 274 | 2020 |
CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ... Cell reports 17 (9), 2367-2381, 2016 | 267 | 2016 |
Sensitization of BCL-2–expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737 SR Oakes, F Vaillant, E Lim, L Lee, K Breslin, F Feleppa, S Deb, ... Proceedings of the National Academy of Sciences 109 (8), 2766-2771, 2012 | 223 | 2012 |
Targeting CDK2 in cancer: challenges and opportunities for therapy S Tadesse, AT Anshabo, N Portman, E Lim, W Tilley, CE Caldon, S Wang Drug discovery today 25 (2), 406-413, 2020 | 196 | 2020 |
The natural history of hormone receptor-positive breast cancer MD Elgene Lim, O Metzger-Filho, EP Winer Oncology 26 (8), 688, 2012 | 195 | 2012 |
The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer TE Hickey, LA Selth, KM Chia, G Laven-Law, HH Milioli, D Roden, ... Nature medicine 27 (2), 310-320, 2021 | 168 | 2021 |
IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel ZN Wee, SMJM Yatim, VK Kohlbauer, M Feng, JY Goh, Y Bao, PL Lee, ... Nature communications 6 (1), 8746, 2015 | 167 | 2015 |
PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination–mediated DNA repair Y Hu, SA Petit, SB Ficarro, KJ Toomire, A Xie, E Lim, SA Cao, E Park, ... Cancer discovery 4 (12), 1430-1447, 2014 | 165 | 2014 |