| 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ... European Journal of Medicinal Chemistry 86, 48-59, 2014 | 120 | 2014 |
| Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death EB da Silva, DAO e Silva, AR Oliveira, CH da Silva Mendes, ... European journal of medicinal chemistry 130, 39-50, 2017 | 56 | 2017 |
| Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification SFP Braga, LC Martins, EB da Silva, PAS Júnior, SMF Murta, ... Bioorganic & medicinal chemistry 25 (6), 1889-1900, 2017 | 49 | 2017 |
| Small-molecule thioesters as SARS-CoV-2 main protease inhibitors: enzyme inhibition, structure–activity relationships, antiviral activity, and X-ray structure determination T Pillaiyar, P Flury, N Krüger, H Su, L Schäkel, E Barbosa Da Silva, ... Journal of Medicinal Chemistry 65 (13), 9376-9395, 2022 | 47 | 2022 |
| Computer-aided design of 1, 4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases LR Silva, AS Guimaraes, J do Nascimento, IJ do Santos Nascimento, ... Bioorganic & Medicinal Chemistry 41, 116213, 2021 | 39 | 2021 |
| Trypanosomal cysteine peptidases: target validation and drug design strategies EB da Silva, GA do Nascimento Pereira, RS Ferreira Comprehensive analysis of parasite biology: From metabolism to drug …, 2016 | 27 | 2016 |
| Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors E Barbosa da Silva, DA Rocha, IS Fortes, W Yang, L Monti, ... Journal of Medicinal Chemistry 64 (17), 13054-13071, 2021 | 26 | 2021 |
| Discovery and characterization of trypanocidal cysteine protease inhibitors from the ‘malaria box’ GAN Pereira, EB da Silva, SFP Braga, PG Leite, LC Martins, RP Vieira, ... European journal of medicinal chemistry 179, 765-778, 2019 | 26 | 2019 |
| Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2 LH Santos, T Kronenberger, RG Almeida, EB Silva, REO Rocha, ... Journal of Chemical Information and Modeling 62 (24), 6553-6573, 2022 | 25 | 2022 |
| Phthaloyl amino acids as anti-inflammatory and immunomodulatory prototypes ACL Leite, FF Barbosa, MVO Cardoso, DRM Moreira, LCD Coêlho, ... Medicinal Chemistry Research 23, 1701-1708, 2014 | 25 | 2014 |
| Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design E Barbosa da Silva, E Dall, P Briza, H Brandstetter, RS Ferreira Acta Crystallographica Section F: Structural Biology Communications 75 (6 …, 2019 | 20 | 2019 |
| 2-(phenylthio) ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity MV de Oliveira Cardoso, GB de Oliveira Filho, LRP de Siqueira, ... European Journal of Medicinal Chemistry 180, 191-203, 2019 | 19 | 2019 |
| Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi E Barbosa Da Silva, V Sharma, L Hernandez-Alvarez, AH Tang, A Stoye, ... Journal of Medicinal Chemistry 65 (5), 4255-4269, 2022 | 17 | 2022 |
| Sales Júnior SFP Braga, LC Martins, EB da Silva PA, Murta, SMF, Romanha, AJ, Soh, WT, Brandstetter, H., Ferreira, RS, & de …, 2017 | 16 | 2017 |
| From rational design to serendipity: discovery of novel thiosemicarbazones as potent trypanocidal compounds SFP Braga, VC Santos, RP Vieira, EB da Silva, L Monti, SH Krake, ... European Journal of Medicinal Chemistry 244, 114876, 2022 | 6 | 2022 |
| Oliveira e Silva DA, Oliveira AR, da Silva Mendes CH, dos Santos TAR, da Silva AC, de Castro MCA, Ferreira RS, Moreira DRM, de Oliveira Cardoso MV, et al. Desing and synthesis … EB Da Silva Eur. J. Med. Chem 130, 39-50, 2017 | 6 | 2017 |
| Oliveira e Silva D, Oliveira A, da Silva Mendes C, dos Santos T, da Silva A, et al. Design and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which … E da Silva European Journal of Medicinal Chemistry 130, 39-50, 2017 | 6 | 2017 |
| Identification of Leucinostatins from Ophiocordyceps sp. as Antiparasitic Agents against Trypanosoma cruzi JA Bernatchez, YS Kil, E Barbosa da Silva, D Thomas, LI McCall, ... ACS omega 7 (9), 7675-7682, 2022 | 5 | 2022 |
| Eur. J. Med. Chem. M Cardoso, LRP de Siqueira, EB da Silva, LB Costa, MZ Hernandes, ... | 5 | 2014 |
| The importance of good practices and false hits for QSAR-driven virtual screening real application: a SARS-CoV-2 main protease (Mpro) case study MSM Serafim, SQ Pantaleão, EB da Silva, JH McKerrow, AJ O’Donoghue, ... Frontiers in Drug Discovery 3, 1237655, 2023 | 4 | 2023 |
