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Andrew C. Kruse
Andrew C. Kruse
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
在 hms.harvard.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Crystal structure of the β2 adrenergic receptor–Gs protein complex
SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ...
Nature 477 (7366), 549-555, 2011
34812011
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ...
Nature 485 (7398), 321-326, 2012
16142012
Activation and allosteric modulation of a muscarinic acetylcholine receptor
AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ...
Nature 504 (7478), 101-106, 2013
9752013
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
K Haga, AC Kruse, H Asada, T Yurugi-Kobayashi, M Shiroishi, C Zhang, ...
Nature 482 (7386), 547-551, 2012
9312012
Structure and dynamics of the M3 muscarinic acetylcholine receptor
AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ...
Nature 482 (7386), 552-556, 2012
9262012
Structure of the δ-opioid receptor bound to naltrindole
S Granier, A Manglik, AC Kruse, TS Kobilka, FS Thian, WI Weis, ...
Nature 485 (7398), 400-404, 2012
8322012
Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody
AM Ring, A Manglik, AC Kruse, MD Enos, WI Weis, KC Garcia, BK Kobilka
Nature 502 (7472), 575-579, 2013
5432013
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ...
Nature methods 7 (12), 1003-1008, 2010
5272010
SEDS proteins are a widespread family of bacterial cell wall polymerases
AJ Meeske, EP Riley, WP Robins, T Uehara, JJ Mekalanos, D Kahne, ...
Nature 537 (7622), 634-638, 2016
5102016
Crystal structure of the human σ1 receptor
HR Schmidt, S Zheng, E Gurpinar, A Koehl, A Manglik, AC Kruse
Nature 532 (7600), 527-530, 2016
4842016
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide
AK Shukla, A Manglik, AC Kruse, K Xiao, RI Reis, WC Tseng, DP Staus, ...
Nature 497 (7447), 137-141, 2013
4752013
Muscarinic acetylcholine receptors: novel opportunities for drug development
AC Kruse, BK Kobilka, D Gautam, PM Sexton, A Christopoulos, J Wess
Nature reviews Drug discovery 13 (7), 549-560, 2014
4482014
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
C McMahon, AS Baier, R Pascolutti, M Wegrecki, S Zheng, JX Ong, ...
Nature structural & molecular biology 25 (3), 289-296, 2018
4382018
Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging
RL Maute, SR Gordon, AT Mayer, MN McCracken, A Natarajan, NG Ring, ...
Proceedings of the National Academy of Sciences 112 (47), E6506-E6514, 2015
3892015
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3382016
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex
JJ Adams, S Narayanan, B Liu, ME Birnbaum, AC Kruse, NA Bowerman, ...
Immunity 35 (5), 681-693, 2011
2992011
Protein design and variant prediction using autoregressive generative models
JE Shin, AJ Riesselman, AW Kollasch, C McMahon, E Simon, C Sander, ...
Nature communications 12 (1), 2403, 2021
2972021
FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein
A Taguchi, MA Welsh, LS Marmont, W Lee, M Sjodt, AC Kruse, D Kahne, ...
Nature microbiology 4 (4), 587-594, 2019
2932019
Identification of the gene that codes for the σ2 receptor
A Alon, HR Schmidt, MD Wood, JJ Sahn, SF Martin, AC Kruse
Proceedings of the National Academy of Sciences 114 (27), 7160-7165, 2017
2932017
Crystal structure of a full-length human tetraspanin reveals a cholesterol-binding pocket
B Zimmerman, B Kelly, BJ McMillan, TCM Seegar, RO Dror, AC Kruse, ...
Cell 167 (4), 1041-1051. e11, 2016
2862016
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