| Effect of P-glycoprotein (P-gp) inducers on exposure of P-gp substrates: review of clinical drug–drug interaction studies M Elmeliegy, M Vourvahis, C Guo, DD Wang Clinical pharmacokinetics 59, 699-714, 2020 | 200 | 2020 |
| Sandwich-cultured hepatocytes as a tool to study drug disposition and drug-induced liver injury K Yang, C Guo, JL Woodhead, RLS Claire III, PB Watkins, SQ Siler, ... Journal of pharmaceutical sciences 105 (2), 443-459, 2016 | 72 | 2016 |
| Reversing effects of lignans on CCl4-induced hepatic CYP450 down regulation by attenuating oxidative stress Y Xie, H Hao, H Wang, C Guo, A Kang, G Wang Journal of ethnopharmacology 155 (1), 213-221, 2014 | 56 | 2014 |
| Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats L Zhang, L Liu, X Chu, H Xie, L Cao, C Guo, B Cao, M Li, G Wang, H Hao Acta Pharmacologica Sinica 35 (3), 363-372, 2014 | 47 | 2014 |
| Farnesoid X receptor agonists obeticholic acid and chenodeoxycholic acid increase bile acid efflux in sandwich-cultured human hepatocytes: functional evidence and mechanisms C Guo, C LaCerte, JE Edwards, KR Brouwer, KLR Brouwer Journal of Pharmacology and Experimental Therapeutics 365 (2), 413-421, 2018 | 41 | 2018 |
| Quantitative prediction of OATP‐mediated drug‐drug interactions with model‐based analysis of endogenous biomarker kinetics K Yoshida, C Guo, R Sane CPT: Pharmacometrics & Systems Pharmacology 7 (8), 517-524, 2018 | 32 | 2018 |
| Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes C Guo, L He, D Yao, A Jiye, B Cao, J Ren, G Wang, G Pan Toxicology letters 224 (1), 93-100, 2014 | 32 | 2014 |
| Dysregulations of UDP-glucuronosyltransferases in rats with valproic acid and high fat diet induced fatty liver L Zhang, X Chu, H Wang, H Xie, C Guo, L Cao, X Zhou, G Wang, H Hao European journal of pharmacology 721 (1-3), 277-285, 2013 | 29 | 2013 |
| Prediction of altered bile acid disposition due to inhibition of multiple transporters: an integrated approach using sandwich-cultured hepatocytes, mechanistic modeling, and … C Guo, K Yang, KR Brouwer, RLS Claire, KLR Brouwer Journal of Pharmacology and Experimental Therapeutics 358 (2), 324-333, 2016 | 23 | 2016 |
| First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors O Hamid, AA Chiappori, JA Thompson, T Doi, S Hu-Lieskovan, ... Journal for immunotherapy of cancer 10 (10), 2022 | 22 | 2022 |
| Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold J Zhu, M Ning, C Guo, L Zhang, G Pan, Y Leng, J Shen European journal of medicinal chemistry 69, 55-68, 2013 | 22 | 2013 |
| Opposite regulation of hepatic breast cancer resistance protein in type 1 and 2 diabetes mellitus L He, Y Yang, C Guo, D Yao, H Liu, J Sheng, W Zhou, J Ren, X Liu, G Pan European journal of pharmacology 724, 185-192, 2014 | 11 | 2014 |
| Oncology dose optimization paradigms: knowledge gained and extrapolated from approved oncology therapeutics RK Mittapalli, C Guo, SK Drescher, D Yin Cancer Chemotherapy and Pharmacology 90 (3), 207-216, 2022 | 9 | 2022 |
| Prediction of hepatic efflux transporter-mediated drug interactions: when is it optimal to measure intracellular unbound fraction of inhibitors? C Guo, K Yang, M Liao, CQ Xia, KR Brouwer, KLR Brouwer Journal of pharmaceutical sciences 106 (9), 2401-2406, 2017 | 6 | 2017 |
| PK/PD model‐informed dose selection for oncology phase I expansion: case study based on PF‐06939999, a PRMT5 inhibitor C Guo, KH Liao, M Li, IM Wang, N Shaik, D Yin CPT: Pharmacometrics & Systems Pharmacology 12 (11), 1619-1625, 2023 | 5 | 2023 |
| Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment C Guo, Y Yu, J Chakrabarti, SA Piha‐Paul, R Moroose, A Plotka, H Shi, ... British journal of clinical pharmacology 88 (7), 3392-3403, 2022 | 5 | 2022 |
| Hepatic transporter alterations by nuclear receptor agonist T0901317 in sandwich-cultured human hepatocytes: proteomic analysis and PBPK modeling to evaluate drug-drug … K Ito, N Sjöstedt, MM Malinen, C Guo, KLR Brouwer Journal of Pharmacology and Experimental Therapeutics 373 (2), 261-268, 2020 | 2 | 2020 |
| Probe cocktail to assess transporter function in sandwich-cultured human hepatocytes C Guo, KR Brouwer, PW Stewart, C Moseley, KLR Brouwer Journal of pharmacy & pharmaceutical sciences: a publication of the Canadian …, 2019 | 2 | 2019 |
| 葡萄糖和胰岛素调节三明治肝细胞中胆酸相关转运体表达及功能 赫蕾， 郭岑， 姚丹， 盛晶晶， 潘国宇， 刘晓东 中国临床药理学与治疗学 18 (8), 847, 2013 | 1 | 2013 |
| Application of d-Penicillamine2, 5-enkephalin to characterization of sandwich-cultured hepatocytes transport activities C GUO, L HE, D YAO, G PAN, G WANG Chinese Journal of Clinical Pharmacology and Therapeutics 18 (5), 506, 2013 | 1 | 2013 |
