The spatial landscape of progression and immunoediting in primary melanoma at single-cell resolution AJ Nirmal, Z Maliga, T Vallius, B Quattrochi, AA Chen, CA Jacobson, ... Cancer Discovery 12 (6), 1518-1541, 2022 | 112 | 2022 |
The immunology of hormone receptor positive breast cancer J Goldberg, RG Pastorello, T Vallius, J Davis, YX Cui, J Agudo, AG Waks, ... Frontiers in immunology 12, 674192, 2021 | 95 | 2021 |
Serum HE4 and CA125 as predictors of response and outcome during neoadjuvant chemotherapy of advanced high-grade serous ovarian cancer T Vallius, J Hynninen, A Auranen, O Carpén, J Matomäki, S Oksa, ... Tumor Biology 35, 12389-12395, 2014 | 71 | 2014 |
18F-FDG-PET/CT can identify histopathological non-responders to platinum-based neoadjuvant chemotherapy in advanced epithelial ovarian cancer T Vallius, A Peter, A Auranen, O Carpén, J Kemppainen, J Matomäki, ... Gynecologic oncology 140 (1), 29-35, 2016 | 52 | 2016 |
MITI minimum information guidelines for highly multiplexed tissue images D Schapiro, C Yapp, A Sokolov, SM Reynolds, YA Chen, D Sudar, Y Xie, ... Nature methods 19 (3), 262-267, 2022 | 45 | 2022 |
Mathematical modeling predicts response to chemotherapy and drug combinations in ovarian cancer E Kozłowska, A Färkkilä, T Vallius, O Carpén, J Kemppainen, S Grénman, ... Cancer research 78 (14), 4036-4044, 2018 | 40 | 2018 |
18F-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancer T Vallius, J Hynninen, J Kemppainen, V Alves, K Auranen, J Matomäki, ... European journal of nuclear medicine and molecular imaging 45, 1224-1232, 2018 | 39 | 2018 |
Clinical efficacy and molecular response correlates of the WEE1 inhibitor adavosertib combined with cisplatin in patients with metastatic triple-negative breast cancer TE Keenan, T Li, T Vallius, JL Guerriero, N Tayob, B Kochupurakkal, ... Clinical Cancer Research 27 (4), 983-991, 2021 | 36 | 2021 |
UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues C Yapp, E Novikov, WD Jang, T Vallius, YA Chen, M Cicconet, Z Maliga, ... Communications Biology 5 (1), 1263, 2022 | 25 | 2022 |
Postoperative human epididymis protein 4 predicts primary therapy outcome in advanced epithelial ovarian cancer T Vallius, J Hynninen, A Auranen, J Matomäki, S Oksa, P Roering, ... Tumor Biology 39 (2), 1010428317691189, 2017 | 23 | 2017 |
Virtual clinical trials identify effective combination therapies in ovarian cancer E Kozłowska, T Vallius, J Hynninen, S Hietanen, A Färkkilä, S Hautaniemi Scientific reports 9 (1), 18678, 2019 | 16 | 2019 |
Clinical value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in response evaluation after primary treatment of advanced epithelial ovarian cancer J Hynninen, M Laasik, T Vallius, J Kemppainen, S Grönroos, J Virtanen, ... Clinical Oncology 30 (8), 507-514, 2018 | 10 | 2018 |
Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer IM Launonen, EP Erkan, I Niemiec, A Junquera, M Hincapie-Otero, ... bioRxiv, 2024 | 3 | 2024 |
Quality control for single cell analysis of high-plex tissue profiles using CyLinter GJ Baker, E Novikov, Z Zhao, T Vallius, JA Davis, JR Lin, JL Muhlich, ... bioRxiv, 2024 | 2 | 2024 |
Abstract P4-04-06: integrative analysis of single-cell transcriptomic and spatial profiles characterized distinct tumor microenvironment phenotypes in hormone receptor positive … K Shimada, YX Cui, JS Goldberg, R Pastorello, J Davis, T Vallius, L Kania, ... Cancer Research 82 (4_Supplement), P4-04-06-P4-04-06, 2022 | 1 | 2022 |
Integrative analysis of single-cell transcriptomic and spatial profiles characterized distinct tumor microenvironment phenotypes in hormone receptor positive (HR plus) breast … K Shimada, YX Cui, JS Goldberg, R Pastorello, J Davis, T Vallius, L Kania, ... CANCER RESEARCH 82 (4), 2022 | 1 | 2022 |
Total metabolic tumor volume change during neoadjuvant chemotherapy in 18f-fdg-pet/ct predicts outcome in advanced epithelial ovarian cancer T Vallius, J Hynninen, J Kemppainen, V Alves, S Oksa, J Matomaki, ... International Journal of Gynecological Cancer 26, 728-728, 2016 | 1 | 2016 |
SpatialCells: automated profiling of tumor microenvironments with spatially resolved multiplexed single-cell data G Wan, Z Maliga, B Yan, T Vallius, Y Shi, S Khattab, C Chang, AJ Nirmal, ... Briefings in Bioinformatics 25 (3), bbae189, 2024 | | 2024 |
Spatial multi-omics profiling of tumor cell phenotypes in primary cutaneous melanoma at single-cell resolution T Vallius, E Novikov, AN Johnson, S Yingxiao, R Pelletier, S Pant, ... Cancer Research 84 (6_Supplement), 2593-2593, 2024 | | 2024 |
Abstract A080: CD8+ T-cell interplay with myeloid cells as spatial determinant of chemotherapy response in the tumor microenvironment of metastatic high-grade serous ovarian cancer IMP Launonen, EP Erkan, I Niemiec, AJ Mencía, A Szabo, F Perez, ... Cancer Research 84 (5_Supplement_2), A080-A080, 2024 | | 2024 |