CaMKII determines mitochondrial stress responses in heart MA Joiner, OM Koval, J Li, BJ He, C Allamargot, Z Gao, ED Luczak, ... Nature 491 (7423), 269-273, 2012 | 429 | 2012 |
Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation A Purohit, AG Rokita, X Guan, B Chen, OM Koval, N Voigt, S Neef, T Sowa, ... Circulation 128 (16), 1748-1757, 2013 | 338 | 2013 |
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII M Luo, X Guan, ED Luczak, D Lang, W Kutschke, Z Gao, J Yang, P Glynn, ... The Journal of clinical investigation 123 (3), 1262-1274, 2013 | 280 | 2013 |
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone BJ He, MLA Joiner, MV Singh, ED Luczak, PD Swaminathan, OM Koval, ... Nature medicine 17 (12), 1610-1618, 2011 | 265 | 2011 |
Oxidized CaMKII causes cardiac sinus node dysfunction in mice PD Swaminathan, A Purohit, S Soni, N Voigt, MV Singh, AV Glukhov, ... The Journal of clinical investigation 121 (8), 3277-3288, 2011 | 248 | 2011 |
Sex-based cardiac physiology ED Luczak, LA Leinwand Annual review of physiology 71, 1-18, 2009 | 185 | 2009 |
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart TP Rasmussen, Y Wu, MA Joiner, OM Koval, NR Wilson, ED Luczak, ... Proceedings of the National Academy of Sciences 112 (29), 9129-9134, 2015 | 180 | 2015 |
The mitochondrial uniporter controls fight or flight heart rate increases Y Wu, TP Rasmussen, OM Koval, MA Joiner, DD Hall, B Chen, ED Luczak, ... Nature communications 6 (1), 6081, 2015 | 163 | 2015 |
CaMKII oxidative activation and the pathogenesis of cardiac disease ED Luczak, ME Anderson Journal of molecular and cellular cardiology 73, 112-116, 2014 | 156 | 2014 |
CaV1.2 β-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations OM Koval, X Guan, Y Wu, M Joiner, Z Gao, B Chen, IM Grumbach, ... Proceedings of the National Academy of Sciences 107 (11), 4996-5000, 2010 | 155 | 2010 |
MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction MV Singh, PD Swaminathan, ED Luczak, W Kutschke, RM Weiss, ... Journal of molecular and cellular cardiology 52 (5), 1135-1144, 2012 | 130 | 2012 |
Soy diet worsens heart disease in mice BL Stauffer, JP Konhilas, ED Luczak, LA Leinwand The Journal of clinical investigation 116 (1), 209-216, 2006 | 111 | 2006 |
Excessive O-GlcNAcylation Causes Heart Failure and Sudden Death P Umapathi, OO Mesubi, PS Banerjee, N Abrol, Q Wang, ED Luczak, ... Circulation 143 (17), 1687-1703, 2021 | 79 | 2021 |
CaMKII is essential for the proasthmatic effects of oxidation PN Sanders, OM Koval, OA Jaffer, AM Prasad, TR Businga, JA Scott, ... Science translational medicine 5 (195), 195ra97-195ra97, 2013 | 69 | 2013 |
Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy ED Luczak, Y Wu, JM Granger, MA Joiner, NR Wilson, A Gupta, ... Nature communications 11 (1), 4416, 2020 | 63 | 2020 |
Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms OO Mesubi, AG Rokita, N Abrol, Y Wu, B Chen, Q Wang, JM Granger, ... The Journal of clinical investigation 131 (2), 2021 | 49 | 2021 |
Diet and sex modify exercise and cardiac adaptation in the mouse JP Konhilas, H Chen, E Luczak, LA McKee, J Regan, PA Watson, ... American Journal of Physiology-Heart and Circulatory Physiology 308 (2 …, 2015 | 46 | 2015 |
Oxidative activation of the Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis LJ Zhu, PJ Klutho, JA Scott, L Xie, ED Luczak, ME Dibbern, AM Prasad, ... Vascular pharmacology 60 (2), 75-83, 2014 | 46 | 2014 |
Oxidized CaMKII promotes asthma through the activation of mast cells J Qu, DC Do, Y Zhou, E Luczak, W Mitzner, ME Anderson, P Gao JCI insight 2 (1), 2017 | 41 | 2017 |
Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease CD Haines, PA Harvey, ED Luczak, KKB Barthel, JP Konhilas, PA Watson, ... Endocrinology 153 (9), 4470-4479, 2012 | 41 | 2012 |