Mitochondrial oxidative stress in aging and healthspan DF Dai, YA Chiao, DJ Marcinek, HH Szeto, PS Rabinovitch Longevity & healthspan 3, 1-22, 2014 | 505 | 2014 |
Altered proteome turnover and remodeling by short‐term caloric restriction or rapamycin rejuvenate the aging heart DF Dai, PP Karunadharma, YA Chiao, N Basisty, D Crispin, EJ Hsieh, ... Aging cell 13 (3), 529-539, 2014 | 331 | 2014 |
Normalization of NAD+ Redox Balance as a Therapy for Heart Failure CF Lee, JD Chavez, L Garcia-Menendez, Y Choi, ND Roe, YA Chiao, ... Circulation 134 (12), 883-894, 2016 | 301 | 2016 |
The aging heart YA Chiao, PS Rabinovitch Cold Spring Harbor perspectives in medicine 5 (9), a025148, 2015 | 205 | 2015 |
Matrix metalloproteinase-9 deletion attenuates myocardial fibrosis and diastolic dysfunction in ageing mice YA Chiao, TA Ramirez, R Zamilpa, SM Okoronkwo, Q Dai, J Zhang, YF Jin, ... Cardiovascular research 96 (3), 444-455, 2012 | 186 | 2012 |
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts YA Chiao, SC Kolwicz, N Basisty, A Gagnidze, J Zhang, H Gu, D Djukovic, ... Aging (Albany NY) 8 (2), 314, 2016 | 118 | 2016 |
Proteomic analysis identifies in vivo candidate matrix metalloproteinase‐9 substrates in the left ventricle post‐myocardial infarction R Zamilpa, EF Lopez, YA Chiao, Q Dai, GP Escobar, K Hakala, ... Proteomics 10 (11), 2214-2223, 2010 | 108 | 2010 |
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects PP Karunadharma, N Basisty, DF Dai, YA Chiao, EK Quarles, EJ Hsieh, ... Aging cell 14 (4), 547-557, 2015 | 102 | 2015 |
Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction R Zamilpa, J Ibarra, LE de Castro Brás, TA Ramirez, N Nguyen, ... Journal of molecular and cellular cardiology 53 (5), 599-608, 2012 | 99 | 2012 |
Deriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence Y Ma, YA Chiao, R Clark, ER Flynn, A Yabluchanskiy, O Ghasemi, ... Cardiovascular research 106 (3), 421-431, 2015 | 98 | 2015 |
The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age MT Sweetwyne, JW Pippin, DG Eng, KL Hudkins, YA Chiao, ... Kidney international 91 (5), 1126-1145, 2017 | 93 | 2017 |
Multi-analyte profiling reveals matrix metalloproteinase-9 and monocyte chemotactic protein-1 as plasma biomarkers of cardiac aging YA Chiao, Q Dai, J Zhang, J Lin, EF Lopez, SS Ahuja, YM Chou, ... Circulation: Cardiovascular Genetics 4 (4), 455-462, 2011 | 92 | 2011 |
Texas 3-step decellularization protocol: looking at the cardiac extracellular matrix LE de Castro Brás, TA Ramirez, KY DeLeon-Pennell, YA Chiao, Y Ma, ... Journal of proteomics 86, 43-52, 2013 | 90 | 2013 |
Late-life restoration of mitochondrial function reverses cardiac dysfunction in old mice YA Chiao, H Zhang, M Sweetwyne, J Whitson, YS Ting, N Basisty, ... Elife 9, e55513, 2020 | 86 | 2020 |
Measures of healthspan as indices of aging in mice—a recommendation A Richardson, KE Fischer, JR Speakman, R De Cabo, SJ Mitchell, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 85 | 2016 |
Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction A Yabluchanskiy, Y Ma, YA Chiao, EF Lopez, AP Voorhees, H Toba, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (10 …, 2014 | 83 | 2014 |
Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment E Quarles, N Basisty, YA Chiao, G Merrihew, H Gu, MT Sweetwyne, ... Aging Cell 19 (2), e13086, 2020 | 78 | 2020 |
Mitochondrial-targeted catalase: extended longevity and the roles in various disease models DF Dai, YA Chiao, GM Martin, DJ Marcinek, N Basisty, EK Quarles, ... Progress in Molecular Biology and Translational Science 146, 203-241, 2017 | 75 | 2017 |
Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging Y Ma, YA Chiao, J Zhang, AM Manicone, YF Jin, ML Lindsey Microscopy and Microanalysis 18 (1), 81-90, 2012 | 68 | 2012 |
Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments PP Karunadharma, N Basisty, YA Chiao, DF Dai, R Drake, N Levy, ... The FASEB journal 29 (8), 3582, 2015 | 65 | 2015 |