Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway AA Khutornenko, VV Roudko, BV Chernyak, AB Vartapetian, ... Proceedings of the National Academy of Sciences 107 (29), 12828-12833, 2010 | 199 | 2010 |
Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction J Basquin, VV Roudko, M Rode, C Basquin, B Séraphin, E Conti Molecular cell 48 (2), 207-218, 2012 | 173 | 2012 |
Shared immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors V Roudko, CC Bozkus, T Orfanelli, CB McClain, C Carr, T O’Donnell, ... Cell 183 (6), 1634-1649. e17, 2020 | 144 | 2020 |
Therapeutic immune modulation against solid cancers with intratumoral poly-ICLC: a pilot trial C Kyi, V Roudko, R Sabado, Y Saenger, W Loging, J Mandeli, TH Thin, ... Clinical Cancer Research 24 (20), 4937-4948, 2018 | 114 | 2018 |
Computational prediction and validation of tumor-associated neoantigens V Roudko, B Greenbaum, N Bhardwaj Frontiers in Immunology 11, 27, 2020 | 105 | 2020 |
Towards superior dendritic-cell vaccines for cancer therapy M Saxena, S Balan, V Roudko, N Bhardwaj Nature biomedical engineering 2 (6), 341-346, 2018 | 105 | 2018 |
Spatial CRISPR genomics identifies regulators of the tumor microenvironment M Dhainaut, SA Rose, G Akturk, A Wroblewska, SR Nielsen, ES Park, ... Cell 185 (7), 1223-1239. e20, 2022 | 103 | 2022 |
Immune checkpoint blockade enhances shared neoantigen-induced T-cell immunity directed against mutated calreticulin in myeloproliferative neoplasms C Cimen Bozkus, V Roudko, JP Finnigan, J Mascarenhas, R Hoffman, ... Cancer discovery 9 (9), 1192-1207, 2019 | 82 | 2019 |
Structure and RNA-binding properties of the Not1–Not2–Not5 module of the yeast Ccr4–Not complex V Bhaskar, V Roudko, J Basquin, K Sharma, H Urlaub, B Séraphin, ... Nature structural & molecular biology 20 (11), 1281-1288, 2013 | 80 | 2013 |
Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children ND Beckmann, PH Comella, E Cheng, L Lepow, AG Beckmann, SR Tyler, ... Nature communications 12 (1), 4854, 2021 | 58 | 2021 |
Lynch syndrome and MSI-H cancers: from mechanisms to “off-the-shelf” cancer vaccines V Roudko, C Cimen Bozkus, B Greenbaum, A Lucas, R Samstein, ... Frontiers in immunology 12, 757804, 2021 | 57 | 2021 |
Monocytes re-enter the bone marrow during fasting and alter the host response to infection H Janssen, F Kahles, D Liu, J Downey, LL Koekkoek, V Roudko, ... Immunity 56 (4), 783-796. e7, 2023 | 49 | 2023 |
A shift in lung macrophage composition is associated with COVID-19 severity and recovery ST Chen, MD Park, DM Del Valle, M Buckup, A Tabachnikova, ... Science translational medicine 14 (662), eabn5168, 2022 | 41 | 2022 |
Hybrid gene origination creates human-virus chimeric proteins during infection JSY Ho, M Angel, Y Ma, E Sloan, G Wang, C Martinez-Romero, ... Cell 181 (7), 1502-1517. e23, 2020 | 39 | 2020 |
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness JSY Ho, F Di Tullio, M Schwarz, D Low, D Incarnato, F Gay, T Tabaglio, ... Elife 10, e59654, 2021 | 36 | 2021 |
Sampling the host response to SARS-CoV-2 in hospitals under siege AW Charney, NW Simons, K Mouskas, L Lepow, E Cheng, J Le Berichel, ... Nature Medicine 26 (8), 1157-1158, 2020 | 31 | 2020 |
An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis NM LaMarche, S Hegde, MD Park, BB Maier, L Troncoso, J Le Berichel, ... Nature 625 (7993), 166-174, 2024 | 20 | 2024 |
Widespread immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors V Roudko, CC Bozkus, T Orfanelli, SV Blank, B Greenbaum, N Bhardwaj BioRxiv, 662262, 2019 | 14 | 2019 |
Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis MG Kiss, JE Mindur, AG Yates, D Lee, JF Fullard, A Anzai, WC Poller, ... Immunity 56 (7), 1502-1514. e8, 2023 | 11 | 2023 |
Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition M Dhainaut, SA Rose, G Akturk, A Wroblewska, ES Park, SR Nielsen, ... bioRxiv, 2021.07. 13.451021, 2021 | 5 | 2021 |