Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis A Salminen, UK Gursoy, S Paju, K Hyvärinen, P Mäntylä, K Buhlin, ... Journal of clinical periodontology 41 (5), 442-450, 2014 | 174 | 2014 |
Salivary interleukin‐1β concentration and the presence of multiple pathogens in periodontitis UK Gursoy, E Könönen, VJ Uitto, PJ Pussinen, K Hyvärinen, ... Journal of clinical periodontology 36 (11), 922-927, 2009 | 139 | 2009 |
Detection and quantification of five major periodontal pathogens by single copy gene-based real-time PCR K Hyvärinen, S Laitinen, S Paju, A Hakala, L Suominen-Taipale, ... Innate Immunity 15 (4), 195-204, 2009 | 134 | 2009 |
Use of host‐and bacteria‐derived salivary markers in detection of periodontitis: A cumulative approach UK Gursoy, E Könönen, PJ Pussinen, T Tervahartiala, K Hyvärinen, ... Disease markers 30 (6), 299-305, 2011 | 131 | 2011 |
Mesenchymal stromal cells and their extracellular vesicles enhance the anti-inflammatory phenotype of regulatory macrophages by downregulating the production of interleukin (IL … K Hyvärinen, M Holopainen, V Skirdenko, H Ruhanen, P Lehenkari, ... Frontiers in immunology 9, 771, 2018 | 112 | 2018 |
Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants M Lehto, R Hynynen, K Karjalainen, E Kuismanen, K Hyvärinen, ... Experimental cell research 310 (2), 445-462, 2005 | 106 | 2005 |
A common periodontal pathogen has an adverse association with both acute and stable coronary artery disease K Hyvärinen, P Mäntylä, K Buhlin, S Paju, MS Nieminen, J Sinisalo, ... Atherosclerosis 223 (2), 478-484, 2012 | 101 | 2012 |
ORP2, a homolog of oxysterol binding protein, regulates cellular cholesterol metabolism S Laitinen, M Lehto, S Lehtonen, K Hyvärinen, S Heino, E Lehtonen, ... Journal of lipid research 43 (2), 245-255, 2002 | 92 | 2002 |
Periodontal pathogen carriage, rather than periodontitis, determines the serum antibody levels PJ Pussinen, E Könönen, S Paju, K Hyvärinen, UK Gursoy, S Huumonen, ... Journal of Clinical Periodontology 38 (5), 405-411, 2011 | 87 | 2011 |
Quantitative PCR analysis of salivary pathogen burden in periodontitis A Salminen, KAE Kopra, K Hyvärinen, S Paju, P Mäntylä, K Buhlin, ... Frontiers in cellular and infection microbiology 5, 69, 2015 | 58 | 2015 |
Systemic exposure to a common periodontal pathogen and missing teeth are associated with metabolic syndrome K Hyvärinen, A Salminen, V Salomaa, PJ Pussinen Acta diabetologica 52, 179-182, 2015 | 53 | 2015 |
Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort J Ritari, K Hyvärinen, J Clancy, FinnGen, J Partanen, S Koskela NAR genomics and bioinformatics 2 (2), lqaa030, 2020 | 51 | 2020 |
Genetic risk factors associated with preeclampsia and hypertensive disorders of pregnancy JS Tyrmi, T Kaartokallio, AI Lokki, T Jääskeläinen, E Kortelainen, ... JAMA cardiology 8 (7), 674-683, 2023 | 49 | 2023 |
Combining salivary pathogen and serum antibody levels improves their diagnostic ability in detection of periodontitis JM Liljestrand, UK Gursoy, K Hyvärinen, T Sorsa, AL Suominen, ... Journal of Periodontology 85 (1), 123-131, 2014 | 46 | 2014 |
Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice K Hyvärinen, AM Tuomainen, S Laitinen, IL Bykov, L Tormakangas, ... Infection and immunity 77 (8), 3442-3449, 2009 | 38 | 2009 |
Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells M Holopainen, RA Colas, S Valkonen, F Tigistu-Sahle, K Hyvärinen, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 37 | 2019 |
A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini PPL Lam, K Hyvärinen, M Kauppi, L Cosen-Binker, S Laitinen, S Keränen, ... Molecular biology of the cell 18 (7), 2473-2480, 2007 | 36 | 2007 |
Aggregatibacter actinomycetemcomitans serotypes associate with periodontal and coronary artery disease status M Pietiäinen, KAE Kopra, J Vuorenkoski, A Salminen, S Paju, P Mäntylä, ... Journal of clinical periodontology 45 (4), 413-421, 2018 | 34 | 2018 |
Very low density lipoproteins derived from periodontitis patients facilitate macrophage activation via lipopolysaccharide function KAE Kallio, K Hyvärinen, PT Kovanen, M Jauhiainen, PJ Pussinen Metabolism 62 (5), 661-668, 2013 | 33 | 2013 |
Cross‐reactive saliva IgA antibodies to oxidized LDL and periodontal pathogens in humans R Akhi, C Wang, M Kyrklund, O Kummu, SP Turunen, K Hyvärinen, ... Journal of Clinical Periodontology 44 (7), 682-691, 2017 | 23 | 2017 |