Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway T Brautaset, ON Sekurova, H Sletta, TE Ellingsen, AR Strøm, S Valla, ... Chemistry & biology 7 (6), 395-403, 2000 | 332 | 2000 |
Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon JM Blatny, T Brautaset, HC Winther-Larsen, K Haugan, S Valla Applied and environmental microbiology 63 (2), 370-379, 1997 | 309 | 1997 |
Engineering Escherichia coli for methanol conversion JEN Müller, F Meyer, B Litsanov, P Kiefer, E Potthoff, S Heux, WJ Quax, ... Metabolic engineering 28, 190-201, 2015 | 208 | 2015 |
Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria JM Blatny, T Brautaset, HC Winther-Larsen, P Karunakaran, S Valla Plasmid 38 (1), 35-51, 1997 | 208 | 1997 |
Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids IM Aasen, H Ertesvåg, TMB Heggeset, B Liu, T Brautaset, O Vadstein, ... Applied microbiology and biotechnology 100, 4309-4321, 2016 | 194 | 2016 |
A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli S Balzer, V Kucharova, J Megerle, R Lale, T Brautaset, S Valla Microbial cell factories 12, 1-14, 2013 | 143 | 2013 |
The presence of N-terminal secretion signal sequences leads to strong stimulation of the total expression levels of three tested medically important proteins during high-cell … H Sletta, A Tøndervik, S Hakvåg, TEV Aune, A Nedal, R Aune, G Evensen, ... Applied and environmental microbiology 73 (3), 906-912, 2007 | 142 | 2007 |
In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over … ON Sekurova, T Brautaset, H Sletta, SEF Borgos, ØM Jakobsen, ... Journal of bacteriology 186 (5), 1345-1354, 2004 | 142 | 2004 |
Positively regulated bacterial expression systems T Brautaset, R Lale, S Valla Microbial biotechnology 2 (1), 15-30, 2009 | 115 | 2009 |
Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the … ØM Jakobsen, A Benichou, MC Flickinger, S Valla, TE Ellingsen, ... Journal of bacteriology 188 (8), 3063-3072, 2006 | 112 | 2006 |
Broad-Host-Range Plasmid pJB658 Can Be Used for Industrial-Level Production of a Secreted Host-Toxic Single-Chain Antibody Fragment in Escherichia coli H Sletta, A Nedal, TEV Aune, H Hellebust, S Hakvag, R Aune, ... Applied and environmental microbiology 70 (12), 7033-7039, 2004 | 110 | 2004 |
Production and glucosylation of C50 and C40 carotenoids by metabolically engineered Corynebacterium glutamicum SAE Heider, P Peters-Wendisch, R Netzer, M Stafnes, T Brautaset, ... Applied microbiology and biotechnology 98, 1223-1235, 2014 | 108 | 2014 |
Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50°C T Brautaset, ØM Jakobsen, KD Josefsen, MC Flickinger, TE Ellingsen Applied microbiology and biotechnology 74, 22-34, 2007 | 108 | 2007 |
Methylotrophic Bacillus methanolicus encodes two chromosomal and one plasmid born NAD+ dependent methanol dehydrogenase paralogs with different catalytic and biochemical properties A Krog, TMB Heggeset, JEN Müller, CE Kupper, O Schneider, JA Vorholt, ... PloS one 8 (3), e59188, 2013 | 107 | 2013 |
Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei T Brautaset, H Sletta, A Nedal, SEF Borgos, KF Degnes, I Bakke, ... Chemistry & biology 15 (11), 1198-1206, 2008 | 100 | 2008 |
Methanol as carbon substrate in the bio‐economy: Metabolic engineering of aerobic methylotrophic bacteria for production of value‐added chemicals J Pfeifenschneider, T Brautaset, VF Wendisch Biofuels, Bioproducts and Biorefining 11 (4), 719-731, 2017 | 99 | 2017 |
Biosynthetic pathway for γ-cyclic sarcinaxanthin in Micrococcus luteus: Heterologous expression and evidence for diverse and multiple catalytic functions of C50 carotenoid cyclases R Netzer, MH Stafsnes, T Andreassen, A Goksøyr, P Bruheim, T Brautaset Journal of bacteriology 192 (21), 5688-5699, 2010 | 93 | 2010 |
Genome Sequence of Thermotolerant Bacillus methanolicus: Features and Regulation Related to Methylotrophy and Production of l-Lysine and l-Glutamate from … TMB Heggeset, A Krog, S Balzer, A Wentzel, TE Ellingsen, T Brautaset Applied and environmental microbiology 78 (15), 5170-5181, 2012 | 92 | 2012 |
Methanol‐based cadaverine production by genetically engineered Bacillus methanolicus strains I Nærdal, J Pfeifenschneider, T Brautaset, VF Wendisch Microbial biotechnology 8 (2), 342-350, 2015 | 91 | 2015 |
Metabolic engineering for the microbial production of carotenoids and related products with a focus on the rare C50 carotenoids SAE Heider, P Peters-Wendisch, VF Wendisch, J Beekwilder, T Brautaset Applied microbiology and biotechnology 98, 4355-4368, 2014 | 91 | 2014 |