GSK-3 as potential target for therapeutic intervention in cancer JA McCubrey, LS Steelman, FE Bertrand, NM Davis, M Sokolosky, ... Oncotarget 5 (10), 2881, 2014 | 544 | 2014 |
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention NM Davis, M Sokolosky, K Stadelman, SL Abrams, M Libra, S Candido, ... Oncotarget 5 (13), 4603, 2014 | 322 | 2014 |
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention JA McCubrey, LS Steelman, FE Bertrand, NM Davis, SL Abrams, ... Leukemia 28 (1), 15-33, 2014 | 274 | 2014 |
Stroke genetics informs drug discovery and risk prediction across ancestries A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba, DC Posner, ... Nature 611 (7934), 115-123, 2022 | 217 | 2022 |
Diverse roles of GSK-3: Tumor promoter–tumor suppressor, target in cancer therapy JA McCubrey, NM Davis, SL Abrams, G Montalto, M Cervello, J Basecke, ... Advances in biological regulation 54, 176-196, 2014 | 90 | 2014 |
Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells M Sokolosky, WH Chappell, K Stadelman, SL Abrams, NM Davis, ... Cell cycle 13 (5), 820-833, 2014 | 67 | 2014 |
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations T Ge, MR Irvin, A Patki, V Srinivasasainagendra, YF Lin, HK Tiwari, ... Genome Medicine 14 (1), 70, 2022 | 63 | 2022 |
Advances in targeting signal transduction pathways JA McCubrey, LS Steelman, WH Chappell, L Sun, NM Davis, SL Abrams, ... Oncotarget 3 (12), 1505, 2012 | 60 | 2012 |
Targeting breast cancer initiating cells: advances in breast cancer research and therapy JA McCubrey, NM Davis, SL Abrams, G Montalto, M Cervello, M Libra, ... Advances in biological regulation 56, 81-107, 2014 | 39 | 2014 |
Association of transthyretin Val122Ile variant with incident heart failure among black individuals V Parcha, G Malla, MR Irvin, ND Armstrong, SE Judd, LA Lange, ... Jama 327 (14), 1368-1378, 2022 | 27 | 2022 |
Insights from a large-scale whole-genome sequencing study of systolic blood pressure, diastolic blood pressure, and hypertension TN Kelly, X Sun, KY He, MR Brown, SAG Taliun, JN Hellwege, MR Irvin, ... Hypertension 79 (8), 1656-1667, 2022 | 15 | 2022 |
Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study CG Downie, SF Dimos, SA Bien, Y Hu, BF Darst, LM Polfus, Y Wang, ... Diabetologia 65 (3), 477-489, 2022 | 15 | 2022 |
Epigenome-wide analyses identify two novel associations with recurrent stroke in the vitamin intervention for stroke prevention clinical trial NM Davis Armstrong, WM Chen, MS Brewer, SR Williams, MM Sale, ... Frontiers in Genetics 9, 358, 2018 | 15 | 2018 |
Contribution of common genetic variants to risk of early-onset ischemic stroke T Jaworek, H Xu, BJ Gaynor, JW Cole, K Rannikmae, TM Stanne, ... Neurology 99 (16), e1738-e1754, 2022 | 13 | 2022 |
Genetic contributors of incident stroke in 10,700 African Americans with hypertension: a meta-analysis from the genetics of hypertension associated treatments and reasons for … ND Armstrong, V Srinivasasainagendra, A Patki, RM Tanner, BA Hidalgo, ... Frontiers in Genetics 12, 781451, 2021 | 11 | 2021 |
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics … CW McDonough, HR Warren, JR Jack, AA Motsinger‐Reif, ND Armstrong, ... Clinical Pharmacology & Therapeutics 110 (3), 723-732, 2021 | 11 | 2021 |
The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes F Denorme, ND Armstrong, ML Stoller, I Portier, EA Tugolukova, ... The Journal of Clinical Investigation 133 (18), 2023 | 9 | 2023 |
DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP … NM Davis Armstrong, WM Chen, FC Hsu, MS Brewer, N Cullell, ... Plos one 16 (7), e0254562, 2021 | 5 | 2021 |
Multi-omic analysis of stroke recurrence in African Americans from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial NM Davis Armstrong, KJ Spragley, WM Chen, FC Hsu, MS Brewer, ... Plos one 16 (3), e0247257, 2021 | 5 | 2021 |
Validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations T Ge, A Patki, V Srinivasasainagendra, YF Lin, MR Irvin, HK Tiwari, ... medRxiv, 2021.09. 11.21263413, 2021 | 4 | 2021 |