Charge variant analysis of monoclonal antibodies using direct coupled pH gradient cation exchange chromatography to high-resolution native mass spectrometry F Füssl, K Cook, K Scheffler, A Farrell, S Mittermayr, J Bones Analytical chemistry 90 (7), 4669-4676, 2018 | 150 | 2018 |
Comprehensive characterisation of the heterogeneity of adalimumab via charge variant analysis hyphenated on-line to native high resolution Orbitrap mass spectrometry F Füssl, A Trappe, K Cook, K Scheffler, O Fitzgerald, J Bones MAbs 11 (1), 116-128, 2019 | 106 | 2019 |
Ultra‐fast tandem mass spectrometry scanning combined with monolithic column liquid chromatography increases throughput in proteomic analysis M Batycka, NF Inglis, K Cook, A Adam, D Fraser‐Pitt, DGE Smith, L Main, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2006 | 91 | 2006 |
Hydrophilic strong anion exchange (hSAX) chromatography for highly orthogonal peptide separation of complex proteomes MS Ritorto, K Cook, K Tyagi, PGA Pedrioli, M Trost Journal of proteome research 12 (6), 2449-2457, 2013 | 88 | 2013 |
Semi‐targeted analysis of metabolites using capillary‐flow ion chromatography coupled to high‐resolution mass spectrometry K Burgess, D Creek, P Dewsbury, K Cook, MP Barrett Rapid Communications in Mass Spectrometry 25 (22), 3447-3452, 2011 | 85 | 2011 |
A novel lipidomics workflow for improved human plasma identification and quantification using RPLC-MSn methods and isotope dilution strategies E Rampler, A Criscuolo, M Zeller, Y El Abiead, H Schoeny, G Hermann, ... Analytical Chemistry 90 (11), 6494-6501, 2018 | 81 | 2018 |
Determination of nitrite and nitrate in human serum JM Monaghan, K Cook, D Gara, D Crowther Journal of Chromatography A 770 (1-2), 143-149, 1997 | 66 | 1997 |
Advantages of ion-exchange chromatography for oligonucleotide analysis K Cook, J Thayer Bioanalysis 3 (10), 1109-1120, 2011 | 60 | 2011 |
Inter-laboratory study of an optimised peptide mapping workflow using automated trypsin digestion for monitoring monoclonal antibody product quality attributes S Millán-Martín, C Jakes, S Carillo, T Buchanan, M Guender, ... Analytical and Bioanalytical Chemistry 412, 6833-6848, 2020 | 56 | 2020 |
Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome J Haggarty, M Oppermann, MJ Dalby, RJ Burchmore, K Cook, S Weidt, ... Metabolomics 11, 1465-1470, 2015 | 51 | 2015 |
Nucleic acid separations using superficially porous silica particles ED Close, AO Nwokeoji, D Milton, K Cook, DM Hindocha, EC Hook, ... Journal of Chromatography A 1440, 135-144, 2016 | 48 | 2016 |
Rational selection of reverse phase columns for high throughput LC–MS lipidomics A Criscuolo, M Zeller, K Cook, G Angelidou, M Fedorova Chemistry and physics of lipids 221, 120-127, 2019 | 46 | 2019 |
Characterization and sequence mapping of large RNA and mRNA therapeutics using mass spectrometry CJ Vanhinsbergh, A Criscuolo, JN Sutton, K Murphy, AJK Williamson, ... Analytical Chemistry 94 (20), 7339-7349, 2022 | 44 | 2022 |
A comprehensive study to protein retention in hydrophobic interaction chromatography M Baca, J De Vos, G Bruylants, K Bartik, X Liu, K Cook, S Eeltink Journal of Chromatography B 1032, 182-188, 2016 | 43 | 2016 |
Cracking proteoform complexity of ovalbumin with anion-exchange chromatography–high-resolution mass spectrometry under native conditions F Fussl, A Criscuolo, K Cook, K Scheffler, J Bones Journal of proteome research 18 (10), 3689-3702, 2019 | 40 | 2019 |
New insights into the chromatography mechanisms of ion-exchange charge variant analysis: Dispelling myths and providing guidance for robust method optimization J Baek, AB Schwahn, S Lin, CA Pohl, M De Pra, SM Tremintin, K Cook Analytical chemistry 92 (19), 13411-13419, 2020 | 37 | 2020 |
Simultaneous identification of selenium-containing glutathione species in selenised yeast by on-line HPLC with ICP-MS and electrospray ionisation quadrupole time of flight … HG Infante, G O’Connor, M Rayman, R Hearn, K Cook Journal of Analytical Atomic Spectrometry 21 (11), 1256-1263, 2006 | 37 | 2006 |
Capabilities of mixed-mode liquid chromatography coupled to inductively coupled plasma mass spectrometry for the simultaneous speciation analysis of inorganic and organically … E Peachey, K Cook, A Castles, C Hopley, H Goenaga-Infante Journal of Chromatography A 1216 (42), 7001-7006, 2009 | 33 | 2009 |
Development and qualification of an antibody rapid deglycosylation method KS Cook, K Bullock, T Sullivan Biologicals 40 (2), 109-117, 2012 | 28 | 2012 |
Intact multi-attribute method (iMAM): A flexible tool for the analysis of monoclonal antibodies S Carillo, A Criscuolo, F Füssl, K Cook, J Bones European Journal of Pharmaceutics and Biopharmaceutics 177, 241-248, 2022 | 20 | 2022 |