Oligodendrocyte, astrocyte, and microglia crosstalk in myelin development, damage, and repair HS Domingues, CC Portugal, R Socodato, JB Relvas Frontiers in cell and developmental biology 4, 71, 2016 | 475 | 2016 |
Nitric oxide in the nervous system: biochemical, developmental, and neurobiological aspects M Cossenza, R Socodato, CC Portugal, ICL Domith, LFH Gladulich, ... Vitamins & Hormones 96, 79-125, 2014 | 101 | 2014 |
Microglia and alcohol meet at the crossroads: Microglia as critical modulators of alcohol neurotoxicity JF Henriques, CC Portugal, T Canedo, JB Relvas, T Summavielle, ... Toxicology letters 283, 21-31, 2018 | 76 | 2018 |
Caveolin-1–mediated internalization of the vitamin C transporter SVCT2 in microglia triggers an inflammatory phenotype CC Portugal, R Socodato, T Canedo, CM Silva, T Martins, VSM Coreixas, ... Science signaling 10 (472), eaal2005, 2017 | 74 | 2017 |
Microglia dysfunction caused by the loss of rhoa disrupts neuronal physiology and leads to neurodegeneration R Socodato, CC Portugal, T Canedo, A Rodrigues, TO Almeida, ... Cell Reports 31 (12), 2020 | 66 | 2020 |
Structure and function of a novel antioxidant peptide from the skin of tropical frogs EA Barbosa, A Oliveira, A Plácido, R Socodato, CC Portugal, AC Mafud, ... Free Radical Biology and Medicine 115, 68-79, 2018 | 63 | 2018 |
A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection EB Andrade, A Magalhães, A Puga, M Costa, J Bravo, CC Portugal, ... Nature communications 9 (1), 3138, 2018 | 62 | 2018 |
Maternal separation effects on mother rodents’ behaviour: A systematic review RL Alves, CC Portugal, T Summavielle, F Barbosa, A Magalhães Neuroscience & Biobehavioral Reviews 117, 98-109, 2020 | 56 | 2020 |
c‐Src function is necessary and sufficient for triggering microglial cell activation R Socodato, CC Portugal, I Domith, NA Oliveira, VSM Coreixas, EC Loiola, ... Glia 63 (3), 497-511, 2015 | 55 | 2015 |
c-Src deactivation by the polyphenol 3-O-caffeoylquinic acid abrogates reactive oxygen species-mediated glutamate release from microglia and neuronal excitotoxicity R Socodato, CC Portugal, T Canedo, I Domith, NA Oliveira, ... Free Radical Biology and Medicine 79, 45-55, 2015 | 53 | 2015 |
Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior R Socodato, JF Henriques, CC Portugal, TO Almeida, J Tedim-Moreira, ... Science signaling 13 (650), eaba5754, 2020 | 52 | 2020 |
Nitric oxide modulates sodium vitamin C transporter 2 (SVCT-2) protein expression via protein kinase G (PKG) and nuclear factor-κB (NF-κB) CC Portugal, TG da Encarnação, R Socodato, SR Moreira, D Brudzewsky, ... Journal of Biological Chemistry 287 (6), 3860-3872, 2012 | 52 | 2012 |
Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells TA Mejía-García, CC Portugal, TG Encarnação, MAM Prado, ... Cellular Signalling 25 (12), 2424-2439, 2013 | 51 | 2013 |
Glutamate receptors modulate sodium‐dependent and calcium‐independent vitamin C bidirectional transport in cultured avian retinal cells CC Portugal, VS Miya, KC Calaza, RAM Santos, R Paes‐de‐Carvalho Journal of neurochemistry 108 (2), 507-520, 2009 | 49 | 2009 |
Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine T Canedo, CC Portugal, R Socodato, TO Almeida, AF Terceiro, J Bravo, ... Neuropsychopharmacology 46 (13), 2358-2370, 2021 | 48 | 2021 |
Cytotoxic activity of poly-ɛ-caprolactone lipid-core nanocapsules loaded with lycopene-rich extract from red guava (Psidium guajava L.) on breast cancer cells AG Vasconcelos, MO Valim, AGN Amorim, CP do Amaral, MP de Almeida, ... Food Research International 136, 109548, 2020 | 41 | 2020 |
Vitamin C modulates glutamate transport and NMDA receptor function in the retina I Domith, R Socodato, CC Portugal, AF Munis, AT Duarte‐Silva, ... Journal of neurochemistry 144 (4), 408-420, 2018 | 38 | 2018 |
Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells V Coelho-Santos, R Socodato, C Portugal, RA Leitao, M Rito, M Barbosa, ... Cellular and molecular life sciences 73, 4701-4716, 2016 | 38 | 2016 |
Activation of glutamate receptors promotes a calcium-dependent and transporter-mediated release of purines in cultured avian retinal cells: possible involvement of calcium … R Paes-de-Carvalho, BV Dias, RA Martins, MR Pereira, CC Portugal, ... Neurochemistry international 46 (6), 441-451, 2005 | 37 | 2005 |
Src family kinases (SFKs): critical regulators of microglial homeostatic functions and neurodegeneration in Parkinson's and Alzheimer's diseases CC Portugal, TO Almeida, R Socodato, JB Relvas The FEBS Journal 289 (24), 7760-7775, 2022 | 29 | 2022 |