Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden ML Stone, KB Chiappinelli, H Li, LM Murphy, ME Travers, MJ Topper, ... Proceedings of the National Academy of Sciences 114 (51), E10981-E10990, 2017 | 254 | 2017 |
Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice F Veglia, A Hashimoto, H Dweep, E Sanseviero, A De Leo, E Tcyganov, ... Journal of Experimental Medicine 218 (4), 2021 | 164 | 2021 |
Comparative proteogenomics: combining mass spectrometry and comparative genomics to analyze multiple genomes N Gupta, J Benhamida, V Bhargava, D Goodman, E Kain, I Kerman, ... Genome research 18 (7), 1133-1142, 2008 | 130 | 2008 |
Technical variations in low-input RNA-seq methodologies V Bhargava, SR Head, P Ordoukhanian, M Mercola, S Subramaniam Scientific reports 4 (1), 3678, 2014 | 109 | 2014 |
Activated plasmacytoid dendritic cells regulate type 2 innate lymphoid cell–mediated airway hyperreactivity H Maazi, H Banie, GRA Muench, N Patel, B Wang, I Sankaranarayanan, ... Journal of Allergy and Clinical Immunology 141 (3), 893-905. e6, 2018 | 77 | 2018 |
A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to … L Wang, SM Dehm, DW Hillman, H Sicotte, W Tan, M Gormley, ... Annals of Oncology 29 (2), 352-360, 2018 | 76 | 2018 |
Identification of mechanisms of resistance to treatment with abiraterone acetate or enzalutamide in patients with castration‐resistant prostate cancer (CRPC) SK Pal, J Patel, M He, B Foulk, K Kraft, DA Smirnov, P Twardowski, ... Cancer 124 (6), 1216-1224, 2018 | 71 | 2018 |
Discovery and pharmacological characterization of JNJ-64619178, a novel small-molecule inhibitor of PRMT5 with potent antitumor activity D Brehmer, L Beke, T Wu, HJ Millar, C Moy, W Sun, G Mannens, V Pande, ... Molecular cancer therapeutics 20 (12), 2317-2328, 2021 | 58 | 2021 |
Quantitative transcriptomics using designed primer-based amplification V Bhargava, P Ko, E Willems, M Mercola, S Subramaniam Scientific reports 3 (1), 1740, 2013 | 55 | 2013 |
TIM-3 engagement promotes effector memory T cell differentiation of human antigen-specific CD8 T cells by activating mTORC1 NC Sabins, O Chornoguz, K Leander, F Kaplan, R Carter, M Kinder, ... The Journal of Immunology 199 (12), 4091-4102, 2017 | 45 | 2017 |
Hybrid simulations of stochastic reaction-diffusion processes for modeling intracellular signaling pathways KH Chiam, CM Tan, V Bhargava, G Rajagopal Physical Review E 74 (5), 051910, 2006 | 42 | 2006 |
Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis M Canavan, AM Walsh, V Bhargava, SM Wade, T McGarry, V Marzaioli, ... JCI insight 3 (23), 2018 | 33 | 2018 |
Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells M Canavan, V Marzaioli, T McGarry, V Bhargava, S Nagpal, DJ Veale, ... Clinical & Experimental Immunology 202 (2), 226-238, 2020 | 25 | 2020 |
Identification of therapeutic targets for glioblastoma by network analysis D Friedmann-Morvinski, V Bhargava, S Gupta, IM Verma, S Subramaniam Oncogene 35 (5), 608-620, 2016 | 24 | 2016 |
Functionally Mature CD1c+ Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium M Canavan, V Marzaioli, V Bhargava, S Nagpal, P Gallagher, C Hurson, ... Frontiers in Immunology 12, 745226, 2021 | 11 | 2021 |
Restoration of the type I IFN–IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice MJ Rahman, KB Rodrigues, JA Quiel, Y Liu, V Bhargava, Y Zhao, ... JCI insight 3 (3), 2018 | 10 | 2018 |
Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic ML Stone, KB Chiappinelli, H Li, LM Murphy, ME Travers, MJ Topper, ... Proceedings of the National Academy of Sciences 115 (37), E8583-E8584, 2018 | 6 | 2018 |
Molecular profile changes in patients with castrate-resistant prostate cancer pre-and post-abiraterone/prednisone treatment H Sicotte, KR Kalari, S Qin, SM Dehm, V Bhargava, M Gormley, W Tan, ... Molecular Cancer Research 20 (12), 1739-1750, 2022 | 5 | 2022 |
Association of Wnt pathway activation with prechemotherapy abiraterone acetate resistance in metastatic castration-resistant prostate cancer (mCRPC) by genome … M Kohli, L Wang, S Dehm, DW Hillman, H Sicotte, M Gormley, V Bhargava, ... Journal of Clinical Oncology 35 (6_suppl), 175-175, 2017 | 3 | 2017 |
Neoantigen Peptide Mimics V Krishna, MA Sepulveda, V Bhargava, IS Grewal, K Bachman US Patent App. 17/556,019, 2022 | 2 | 2022 |