Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13458* | 2021 |
Mechanisms of acute axonal degeneration in the optic nerve in vivo J Knöferle, JC Koch, T Ostendorf, U Michel, V Planchamp, P Vutova, ... Proceedings of the National Academy of Sciences 107 (13), 6064-6069, 2010 | 321 | 2010 |
Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study T Hagenacker, CD Wurster, R Günther, O Schreiber-Katz, A Osmanovic, ... The Lancet Neurology 19 (4), 317-325, 2020 | 257 | 2020 |
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease L Tönges, T Frank, L Tatenhorst, KA Saal, JC Koch, ÉM Szegő, M Bähr, ... Brain 135 (11), 3355-3370, 2012 | 198 | 2012 |
Hot-spot KIF5A mutations cause familial ALS D Brenner, R Yilmaz, K Müller, T Grehl, S Petri, T Meyer, J Grosskreutz, ... Brain 141 (3), 688-697, 2018 | 195 | 2018 |
ROCK inhibition in models of neurodegeneration and its potential for clinical translation JC Koch, L Tatenhorst, AE Roser, KA Saal, L Tönges, P Lingor Pharmacology & Therapeutics 189, 1-21, 2018 | 194 | 2018 |
ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS JC Koch, L Tönges, E Barski, U Michel, M Bähr, P Lingor Cell death & disease 5 (5), e1225-e1225, 2014 | 192 | 2014 |
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation TR Doeppner, M Doehring, E Bretschneider, A Zechariah, B Kaltwasser, ... Acta neuropathologica 126, 251-265, 2013 | 181 | 2013 |
Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells LMA Oliveira, LJ Falomir-Lockhart, MG Botelho, KH Lin, P Wales, JC Koch, ... Cell death & disease 6 (11), e1994-e1994, 2015 | 170 | 2015 |
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015. 1100356 DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Erratum to: Guidelines for the use and interpretation of assays for …, 2016 | 165 | 2016 |
Axonal degeneration as a therapeutic target in the CNS P Lingor, JC Koch, L Tönges, M Bähr Cell and tissue research 349, 289-311, 2012 | 149 | 2012 |
Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons JC Koch, F Bitow, J Haack, Z d'Hedouville, JN Zhang, L Tönges, U Michel, ... Cell death & disease 6 (7), e1811-e1811, 2015 | 145 | 2015 |
Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease L Tatenhorst, K Eckermann, V Dambeck, L Fonseca-Ornelas, H Walle, ... Acta neuropathologica communications 4, 1-17, 2016 | 140 | 2016 |
Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis L Tönges, R Günther, M Suhr, J Jansen, A Balck, KA Saal, E Barski, ... Glia 62 (2), 217-232, 2014 | 126 | 2014 |
ROCKing regeneration: Rho kinase inhibition as molecular target for neurorestoration L Tönges, JC Koch, M Bähr, P Lingor Frontiers in molecular neuroscience 4, 39, 2011 | 114 | 2011 |
Safety and effectiveness of long-term intravenous administration of edaravone for treatment of patients with amyotrophic lateral sclerosis S Witzel, A Maier, R Steinbach, J Grosskreutz, JC Koch, A Sarikidi, S Petri, ... JAMA neurology 79 (2), 121-130, 2022 | 109 | 2022 |
Loss‐of‐Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities D Steel, M Zech, C Zhao, KES Barwick, D Burke, D Demailly, KR Kumar, ... Annals of neurology 88 (5), 867-877, 2020 | 82 | 2020 |
Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo L Tönges, T Ostendorf, F Lamballe, M Genestine, R Dono, JC Koch, ... Journal of neurochemistry 117 (5), 892-903, 2011 | 77 | 2011 |
AAV. shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo KA Saal, JC Koch, L Tatenhorst, ÉM Szegő, VT Ribas, U Michel, M Bähr, ... Neurobiology of disease 73, 150-162, 2015 | 72 | 2015 |
Prognostic factors in ALS: a comparison between Germany and China J Dorst, L Chen, A Rosenbohm, J Dreyhaupt, A Hübers, J Schuster, ... Journal of neurology 266, 1516-1525, 2019 | 70 | 2019 |