Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression T Gaur, CJ Lengner, H Hovhannisyan, RA Bhat, PVN Bodine, BS Komm, ... Journal of Biological Chemistry 280 (39), 33132-33140, 2005 | 1406 | 2005 |
Direct cell reprogramming is a stochastic process amenable to acceleration J Hanna, K Saha, B Pando, J Van Zon, CJ Lengner, MP Creyghton, ... Nature 462 (7273), 595-601, 2009 | 1227 | 2009 |
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency J Hanna, S Markoulaki, P Schorderet, BW Carey, C Beard, M Wernig, ... cell 133 (2), 250-264, 2008 | 1141 | 2008 |
Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells T Brambrink, R Foreman, GG Welstead, CJ Lengner, M Wernig, H Suh, ... Cell stem cell 2 (2), 151-159, 2008 | 1082 | 2008 |
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs J Hanna, AW Cheng, K Saha, J Kim, CJ Lengner, F Soldner, JP Cassady, ... Proceedings of the National Academy of Sciences 107 (20), 9222-9227, 2010 | 1019 | 2010 |
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types M Wernig, CJ Lengner, J Hanna, MA Lodato, E Steine, R Foreman, ... Nature biotechnology 26 (8), 916-924, 2008 | 577 | 2008 |
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors JB Lian, A Javed, SK Zaidi, C Lengner, M Montecino, AJ Van Wijnen, ... Critical Reviews™ in Eukaryotic Gene Expression 14 (1&2), 2004 | 554 | 2004 |
Networks and hubs for the transcriptional control of osteoblastogenesis JB Lian, GS Stein, A Javed, AJ Van Wijnen, JL Stein, M Montecino, ... Reviews in Endocrine and Metabolic Disorders 7, 1-16, 2006 | 531 | 2006 |
Oct4 expression is not required for mouse somatic stem cell self-renewal CJ Lengner, FD Camargo, K Hochedlinger, GG Welstead, S Zaidi, ... Cell stem cell 1 (4), 403-415, 2007 | 505 | 2007 |
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ... Cell 141 (5), 872-883, 2010 | 462 | 2010 |
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia MG Kharas, CJ Lengner, F Al-Shahrour, L Bullinger, B Ball, S Zaidi, ... Nature medicine 16 (8), 903-908, 2010 | 419 | 2010 |
Metastable pluripotent states in NOD-mouse-derived ESCs J Hanna, S Markoulaki, M Mitalipova, AW Cheng, JP Cassady, J Staerk, ... Cell stem cell 4 (6), 513-524, 2009 | 410 | 2009 |
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts J Kim, SC Su, H Wang, AW Cheng, JP Cassady, MA Lodato, CJ Lengner, ... Cell stem cell 9 (5), 413-419, 2011 | 311 | 2011 |
Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling CJ Lengner, HA Steinman, J Gagnon, TW Smith, JE Henderson, ... The Journal of cell biology 172 (6), 909-921, 2006 | 304 | 2006 |
Modeling G2019S-LRRK2 sporadic Parkinson's disease in 3D midbrain organoids H Kim, HJ Park, H Choi, Y Chang, H Park, J Shin, J Kim, CJ Lengner, ... Stem Cell Reports 12 (3), 518-531, 2019 | 275 | 2019 |
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function Q Yu, YV Katlinskaya, CJ Carbone, B Zhao, KV Katlinski, H Zheng, ... Cell reports 11 (5), 785-797, 2015 | 245 | 2015 |
In vivo neuronal gene editing via CRISPR–Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer’s disease H Park, J Oh, G Shim, B Cho, Y Chang, S Kim, S Baek, H Kim, J Shin, ... Nature neuroscience 22 (4), 524-528, 2019 | 228 | 2019 |
Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states KP Simeonov, CN Byrns, ML Clark, RJ Norgard, B Martin, BZ Stanger, ... Cancer cell 39 (8), 1150-1162. e9, 2021 | 209 | 2021 |
MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists C Lv, F Li, X Li, Y Tian, Y Zhang, X Sheng, Y Song, Q Meng, S Yuan, ... Nature communications 8 (1), 1036, 2017 | 170 | 2017 |
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs SM Park, RP Deering, Y Lu, P Tivnan, S Lianoglou, F Al-Shahrour, ... Journal of Experimental Medicine 211 (1), 71-87, 2014 | 166 | 2014 |