Photoinduced ligand release from a silicon phthalocyanine dye conjugated with monoclonal antibodies: a mechanism of cancer cell cytotoxicity after near-infrared photoimmunotherapy K Sato, K Ando, S Okuyama, S Moriguchi, T Ogura, S Totoki, H Hanaoka, ... ACS central science 4 (11), 1559-1569, 2018 | 228 | 2018 |
Long time-lapse nanoscopy with spontaneously blinking membrane probes H Takakura, Y Zhang, RS Erdmann, AD Thompson, Y Lin, B McNellis, ... Nature biotechnology 35 (8), 773-780, 2017 | 182 | 2017 |
Super‐resolution imaging of the Golgi in live cells with a bioorthogonal ceramide probe RS Erdmann, H Takakura, AD Thompson, F Rivera‐Molina, ES Allgeyer, ... Angewandte Chemie International Edition 53 (38), 10242-10246, 2014 | 160 | 2014 |
Rational design and development of near‐infrared‐emitting firefly luciferins available in vivo R Kojima, H Takakura, T Ozawa, Y Tada, T Nagano, Y Urano Angewandte Chemie 125 (4), 1213-1217, 2013 | 107 | 2013 |
Development of luciferin analogues bearing an amino group and their application as BRET donors H Takakura, K Sasakura, T Ueno, Y Urano, T Terai, K Hanaoka, T Tsuboi, ... Chemistry–An Asian Journal 5 (9), 2053-2061, 2010 | 79 | 2010 |
Aminoluciferins as functional bioluminogenic substrates of firefly luciferase H Takakura, R Kojima, Y Urano, T Terai, K Hanaoka, T Nagano Chemistry–An Asian Journal 6 (7), 1800-1810, 2011 | 78 | 2011 |
New class of bioluminogenic probe based on bioluminescent enzyme-induced electron transfer: BioLeT H Takakura, R Kojima, M Kamiya, E Kobayashi, T Komatsu, T Ueno, ... Journal of the American Chemical Society 137 (12), 4010-4013, 2015 | 77 | 2015 |
Development of a sensitive bioluminogenic probe for imaging highly reactive oxygen species in living rats R Kojima, H Takakura, M Kamiya, E Kobayashi, T Komatsu, T Ueno, ... Angewandte Chemie International Edition 54 (49), 14768-14771, 2015 | 66 | 2015 |
Changes in plasma membrane damage inducing cell death after treatment with near‐infrared photoimmunotherapy K Nakajima, H Takakura, Y Shimizu, M Ogawa Cancer science 109 (9), 2889-2896, 2018 | 65 | 2018 |
Visualization and quantitative analysis of G protein-coupled receptor− β-arrestin interaction in single cells and specific organs of living mice using split luciferase … H Takakura, M Hattori, M Takeuchi, T Ozawa ACS chemical biology 7 (5), 901-910, 2012 | 61 | 2012 |
Ratiometric bioluminescence indicators for monitoring cyclic adenosine 3′, 5′-monophosphate in live cells based on luciferase-fragment complementation M Takeuchi, Y Nagaoka, T Yamada, H Takakura, T Ozawa Analytical chemistry 82 (22), 9306-9313, 2010 | 35 | 2010 |
Sustained accurate recording of intracellular acidification in living tissues with a photo-controllable bioluminescent protein M Hattori, S Haga, H Takakura, M Ozaki, T Ozawa Proceedings of the National Academy of Sciences 110 (23), 9332-9337, 2013 | 34 | 2013 |
Theoretical and Experimental Studies on the Near‐Infrared Photoreaction Mechanism of a Silicon Phthalocyanine Photoimmunotherapy Dye: Photoinduced Hydrolysis by Radical Anion … M Kobayashi, M Harada, H Takakura, K Ando, Y Goto, T Tsuneda, ... ChemPlusChem 85 (9), 1959-1963, 2020 | 33 | 2020 |
Development of 5′‐and 7′‐Substituted Luciferin Analogues as Acid‐Tolerant Substrates of Firefly Luciferase H Takakura, R Kojima, T Ozawa, T Nagano, Y Urano ChemBioChem 13 (10), 1424-1427, 2012 | 31 | 2012 |
Implantable wireless powered light emitting diode (LED) for near-infrared photoimmunotherapy: device development and experimental assessment in vitro and in vivo K Nakajima, T Kimura, H Takakura, Y Yoshikawa, A Kameda, T Shindo, ... Oncotarget 9 (28), 20048, 2018 | 29 | 2018 |
Anti PD-1 treatment increases [18F]FDG uptake by cancer cells in a mouse B16F10 melanoma model M Tomita, H Yasui, K Higashikawa, K Nakajima, H Takakura, T Shiga, ... EJNMMI research 8, 1-8, 2018 | 27 | 2018 |
Electron donors rather than reactive oxygen species needed for therapeutic photochemical reaction of near-infrared photoimmunotherapy T Kato, R Okada, Y Goto, A Furusawa, F Inagaki, H Wakiyama, ... ACS pharmacology & translational science 4 (5), 1689-1701, 2021 | 25 | 2021 |
Analysis of temporal patterns of GPCR–β-arrestin interactions using split luciferase-fragment complementation M Hattori, M Tanaka, H Takakura, K Aoki, K Miura, T Anzai, T Ozawa Molecular BioSystems 9 (5), 957-964, 2013 | 24 | 2013 |
Molecular Design of d-Luciferin-Based Bioluminescence and 1,2-Dioxetane-Based Chemiluminescence Substrates for Altered Output Wavelength and Detecting … H Takakura Molecules 26 (6), 1618, 2021 | 23 | 2021 |
Photoimmunotherapy: A new cancer treatment using photochemical reactions M Ogawa, H Takakura Bioorganic & Medicinal Chemistry 43, 116274, 2021 | 20 | 2021 |