| Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer H Huang, Z Wang, Y Zhang, RN Pradhan, D Ganguly, R Chandra, ... Cancer Cell 40 (6), 656-673. e7, 2022 | 262 | 2022 |
| Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution AN Hosein, H Huang, Z Wang, K Parmar, W Du, J Huang, A Maitra, ... Journal of Clinical Investigation Insight, 2019 | 257 | 2019 |
| Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution AN Hosein, H Huang, Z Wang, K Parmar, W Du, J Huang, A Maitra, ... Journal of Clinical Oncology 37 (15_suppl), e15739-e15739, 2019 | 257 | 2019 |
| Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor JM Yingling, WT McMillen, L Yan, H Huang, JS Sawyer, J Graff, ... Oncotarget 9 (6), 6659, 2018 | 151 | 2018 |
| Inhibition of discoidin domain receptor 1 reduces collagen-mediated tumorigenicity in pancreatic ductal adenocarcinoma KY Aguilera, H Huang, W Du, MM Hagopian, Z Wang, S Hinz, TH Hwang, ... Molecular cancer therapeutics 16 (11), 2473-2485, 2017 | 105 | 2017 |
| Sitravatinib potentiates immune checkpoint blockade in refractory cancer models W Du, H Huang, N Sorrelle, RA Brekken Journal of Clinical Investigation Insight 3 (21), 2018 | 103 | 2018 |
| Ddr1-induced neutrophil extracellular traps drive pancreatic cancer metastasis J Deng, Y Kang, CC Cheng, X Li, B Dai, MH Katz, T Men, MP Kim, E Koay, ... Journal of Clinical Investigation Insight, 2021 | 78 | 2021 |
| Up-regulation of N-cadherin by collagen I-activated discoidin domain receptor 1 in pancreatic cancer requires the adaptor molecule Shc1 H Huang, RA Svoboda, AJ Lazenby, J Saowapa, N Chaika, K Ding, ... Journal of Biological Chemistry 291 (44), 23208-23223, 2016 | 70 | 2016 |
| Targeting TGFβR2‐mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer H Huang, Y Zhang, V Gallegos, N Sorrelle, MM Zaid, J Toombs, W Du, ... EMBO Molecular Medicine, 2019 | 69 | 2019 |
| Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues N Sorrelle, D Ganguly, ATA Dominguez, Y Zhang, H Huang, LN Dahal, ... Journal of Immunology, 2018 | 52 | 2018 |
| 2-Amino-2, 3-Dihydro-1H-Indene-5-Carboxamide-Based Discoidin Domain Receptors 1 (DDR1) Inhibitors: Design, Synthesis, and In Vivo Anti-pancreatic Cancer Efficacy D Zhu, H Huang, D Pinkas, J Luo, D Ganguly, AE Fox, E Arner, Q Xiang, ... Journal of Medicinal Chemistry, 2019 | 51 | 2019 |
| Loss of E-cadherin and epithelial to mesenchymal transition is not required for cell motility in tissues or for metastasis X Liu, H Huang, N Remmers, MA Hollingsworth Tissue barriers 2 (4), e969112, 2014 | 51 | 2014 |
| Recent advances in understanding cancer-associated fibroblasts in pancreatic cancer H Huang, RA Brekken American Journal of Physiology-Cell Physiology, 2020 | 40 | 2020 |
| The Next Wave of Stroma-Targeting Therapy in Pancreatic Cancer H Huang, RA Brekken Cancer Research 79 (2), 2019 | 40 | 2019 |
| Getting a grip on adhesion: Cadherin switching and collagen signaling H Huang, S Wright, J Zhang, RA Brekken Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2019 | 38 | 2019 |
| Design, Synthesis and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as … XL Z Wang, Y Zhang, D Pinkas, A Fox, J Luo, H Huang, S Cui, Q Xiang, T Xu, Q ... Journal of Medicinal Chemistry, 2018 | 34 | 2018 |
| VEGFR2 activity on myeloid cells mediates immune suppression in the tumor microenvironment Y Zhang, H Huang, M Coleman, A Ziemys, P Gopal, SM Kazmi, ... Journal of Clinical Investigation Insight, 2021 | 28 | 2021 |
| Extracellular matrix induction of intracellular reactive oxygen species H Huang, W Du, RA Brekken Antioxidants & Redox Signaling 27 (12), 774-784, 2017 | 26 | 2017 |
| AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer W Du, NZ Phinney, H Huang, Z Wang, J Westcott, JE Toombs, Y Zhang, ... Molecular Cancer Research, 2021 | 20 | 2021 |
| Targeting TNF-α producing macrophages activate antitumor immunity in pancreatic cancer through IL33 signaling A Dixit, AL Sarver, J Zettervall, H Huang, K Zheng, RA Brekken, ... Journal of Clinical Investigation Insight, 2022 | 17* | 2022 |
