Biochemical and functional characterization of the interaction between pentraxin 3 and C1q AJ Nauta, B Bottazzi, A Mantovani, G Salvatori, U Kishore, WJ Schwaeble, ... European journal of immunology 33 (2), 465-473, 2003 | 442 | 2003 |
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation AJ Nauta, LA Trouw, MR Daha, O Tijsma, R Nieuwland, WJ Schwaeble, ... European journal of immunology 32 (6), 1726-1736, 2002 | 414 | 2002 |
Talin at a glance DR Critchley, AR Gingras Journal of cell science 121 (9), 1345-1347, 2008 | 305 | 2008 |
Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod AR Gingras, WH Ziegler, R Frank, IL Barsukov, GCK Roberts, ... Journal of Biological Chemistry 280 (44), 37217-37224, 2005 | 233 | 2005 |
The structure of the C‐terminal actin‐binding domain of talin AR Gingras, N Bate, BT Goult, L Hazelwood, I Canestrelli, JG Grossmann, ... The EMBO journal 27 (2), 458-469, 2008 | 228 | 2008 |
RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover BT Goult, T Zacharchenko, N Bate, R Tsang, F Hey, AR Gingras, PR Elliott, ... Journal of Biological Chemistry 288 (12), 8238-8249, 2013 | 225 | 2013 |
Integrin connections to the cytoskeleton through talin and vinculin WH Ziegler, AR Gingras, DR Critchley, J Emsley Biochemical Society Transactions 36 (2), 235-239, 2008 | 203 | 2008 |
Activation of a vinculin‐binding site in the talin rod involves rearrangement of a five‐helix bundle E Papagrigoriou, AR Gingras, IL Barsukov, N Bate, IJ Fillingham, B Patel, ... The EMBO journal 23 (15), 2942-2951, 2004 | 203 | 2004 |
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin M Gunawan, N Venkatesan, JT Loh, JF Wong, H Berger, WH Neo, LYJ Li, ... Nature immunology 16 (5), 505-516, 2015 | 186 | 2015 |
Structure of a double ubiquitin‐like domain in the talin head: a role in integrin activation BT Goult, M Bouaouina, PR Elliott, N Bate, B Patel, AR Gingras, ... The EMBO journal 29 (6), 1069-1080, 2010 | 180 | 2010 |
The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi V Ferreira, C Valck, G Sánchez, A Gingras, S Tzima, MC Molina, R Sim, ... The Journal of Immunology 172 (5), 3042-3050, 2004 | 176 | 2004 |
Structural model and functional significance of pH-dependent talin–actin binding for focal adhesion remodeling J Srivastava, G Barreiro, S Groscurth, AR Gingras, BT Goult, DR Critchley, ... Proceedings of the National Academy of Sciences 105 (38), 14436-14441, 2008 | 158 | 2008 |
The Structure of an Interdomain Complex That Regulates Talin Activity*♦ BT Goult, N Bate, NJ Anthis, KL Wegener, AR Gingras, B Patel, ... Journal of biological chemistry 284 (22), 15097-15106, 2009 | 139 | 2009 |
Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation BT Goult, XP Xu, AR Gingras, M Swift, B Patel, N Bate, PM Kopp, ... Journal of structural biology 184 (1), 21-32, 2013 | 135 | 2013 |
A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head I Fillingham, AR Gingras, E Papagrigoriou, B Patel, J Emsley, ... Structure 13 (1), 65-74, 2005 | 133 | 2005 |
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation U Venkatraman Girija, AR Gingras, JE Marshall, R Panchal, MA Sheikh, ... Proceedings of the National Academy of Sciences 110 (34), 13916-13920, 2013 | 109 | 2013 |
Structural determinants of integrin binding to the talin rod AR Gingras, WH Ziegler, AA Bobkov, MG Joyce, D Fasci, M Himmel, ... Journal of biological chemistry 284 (13), 8866-8876, 2009 | 105 | 2009 |
Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod, AR Gingras, KP Vogel, HJ Steinhoff, WH Ziegler, B Patel, J Emsley, ... Biochemistry 45 (6), 1805-1817, 2006 | 100 | 2006 |
Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics N Bate, AR Gingras, A Bachir, R Horwitz, F Ye, B Patel, BT Goult, ... PLoS One 7 (4), e34461, 2012 | 92 | 2012 |
Studies on the morphology and spreading of human endothelial cells define key inter-and intramolecular interactions for talin1 PM Kopp, N Bate, TM Hansen, NPJ Brindle, U Praekelt, E Debrand, ... European journal of cell biology 89 (9), 661-673, 2010 | 87 | 2010 |