Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways GE Hardingham, Y Fukunaga, H Bading Nature neuroscience 5 (5), 405-414, 2002 | 2016 | 2002 |
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders GE Hardingham, H Bading Nature Reviews Neuroscience 11 (10), 682-696, 2010 | 1793 | 2010 |
Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression GE Hardingham, S Chawla, CM Johnson, H Bading Nature 385 (6613), 260-265, 1997 | 919 | 1997 |
The Yin and Yang of NMDA receptor signalling GE Hardingham, H Bading Trends in neurosciences 26 (2), 81-89, 2003 | 865 | 2003 |
Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity GE Hardingham, FJL Arnold, H Bading Nature neuroscience 4 (3), 261-267, 2001 | 649 | 2001 |
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses S Papadia, FX Soriano, F Léveillé, MA Martel, KA Dakin, HH Hansen, ... Nature neuroscience 11 (4), 476-487, 2008 | 605 | 2008 |
CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV S Chawla, GE Hardingham, DR Quinn, H Bading Science 281 (5382), 1505-1509, 1998 | 549 | 1998 |
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability B Bilican, A Serio, SJ Barmada, AL Nishimura, GJ Sullivan, M Carrasco, ... Proceedings of the National Academy of Sciences 109 (15), 5803-5808, 2012 | 410 | 2012 |
A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication GE Hardingham, FJL Arnold, H Bading Nature neuroscience 4 (6), 565-566, 2001 | 365 | 2001 |
Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels GE Hardingham, S Chawla, FH Cruzalegui, H Bading Neuron 22 (4), 789-798, 1999 | 347 | 1999 |
Coupling of the NMDA receptor to neuroprotective and neurodestructive events GE Hardingham Biochemical Society Transactions 37 (6), 1147-1160, 2009 | 332 | 2009 |
Nuclear Ca2+ and the cAMP response element-binding protein family mediate a late phase of activity-dependent neuroprotection S Papadia, P Stevenson, NR Hardingham, H Bading, GE Hardingham Journal of Neuroscience 25 (17), 4279-4287, 2005 | 331 | 2005 |
Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis GE Hardingham, KQ Do Nature Reviews Neuroscience 17 (2), 125-134, 2016 | 318 | 2016 |
Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability FX Soriano, S Papadia, F Hofmann, NR Hardingham, H Bading, ... Journal of Neuroscience 26 (17), 4509-4518, 2006 | 287 | 2006 |
Influence of GluN2 subunit identity on NMDA receptor function DJA Wyllie, MR Livesey, GE Hardingham Neuropharmacology 74, 4-17, 2013 | 284 | 2013 |
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ... Nature communications 8 (1), 15132, 2017 | 283 | 2017 |
Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals J Qiu, YW Tan, AM Hagenston, MA Martel, N Kneisel, PA Skehel, ... Nature communications 4 (1), 2034, 2013 | 274 | 2013 |
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations R Rojo, A Raper, DD Ozdemir, L Lefevre, K Grabert, ... Nature communications 10 (1), 3215, 2019 | 245 | 2019 |
Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated GE Hardingham, H Bading Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1600 (1-2), 148-153, 2002 | 236 | 2002 |
Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes PS Baxter, GE Hardingham Free Radical Biology and Medicine 100, 147-152, 2016 | 227 | 2016 |