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Charles Mordaunt
Charles Mordaunt
Computational Biologist, GSK
在 gsk.com 的电子邮件经过验证 - 首页
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引用次数
引用次数
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Cumulative impact of polychlorinated biphenyl and large chromosomal duplications on DNA methylation, chromatin, and expression of autism candidate genes
KW Dunaway, MS Islam, RL Coulson, SJ Lopez, AV Ciernia, RG Chu, ...
Cell reports 17 (11), 3035-3048, 2016
832016
Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
Y Zhu, CE Mordaunt, DH Yasui, R Marathe, RL Coulson, KW Dunaway, ...
Human molecular genetics 28 (16), 2659-2674, 2019
762019
Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes
CE Mordaunt, JM Jianu, BI Laufer, Y Zhu, H Hwang, KW Dunaway, ...
Genome medicine 12, 1-25, 2020
692020
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex
RL Coulson, DH Yasui, KW Dunaway, BI Laufer, A Vogel Ciernia, Y Zhu, ...
Nature communications 9 (1), 1616, 2018
632018
Epigenomic convergence of neural-immune risk factors in neurodevelopmental disorder cortex
A Vogel Ciernia, BI Laufer, H Hwang, KW Dunaway, CE Mordaunt, ...
Cerebral Cortex 30 (2), 640-655, 2020
422020
Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights
BI Laufer, H Hwang, A Vogel Ciernia, CE Mordaunt, JM LaSalle
Epigenetics 14 (7), 672-684, 2019
382019
Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles
BI Laufer, H Hwang, JM Jianu, CE Mordaunt, IF Korf, I Hertz-Picciotto, ...
Human Molecular Genetics 29 (21), 3465-3476, 2020
372020
Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers
CE Mordaunt, DA Kieffer, NM Shibata, A Członkowska, T Litwin, KH Weiss, ...
Epigenetics & chromatin 12, 1-16, 2019
372019
Placental methylome reveals a 22q13. 33 brain regulatory gene locus associated with autism
Y Zhu, JA Gomez, BI Laufer, CE Mordaunt, JS Mouat, DC Soto, ...
Genome biology 23 (1), 46, 2022
322022
Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease
CE Mordaunt, NM Shibata, DA Kieffer, A Członkowska, T Litwin, KH Weiss, ...
Human molecular genetics 27 (22), 3854-3869, 2018
272018
Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches
A Vogel Ciernia, BI Laufer, KW Dunaway, CE Mordaunt, RL Coulson, ...
Epigenetics 13 (3), 318-330, 2018
262018
A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in …
CE Mordaunt, BY Park, KM Bakulski, JI Feinberg, LA Croen, ...
Molecular autism 10, 1-21, 2019
252019
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons
SJ Lopez, K Dunaway, MS Islam, C Mordaunt, A Vogel Ciernia, ...
Epigenetics 12 (11), 982-990, 2017
212017
Design, synthesis and identification of a new class of triarylmethyl amine compounds as inhibitors of apolipoprotein E production
M Singh, JT Schott, MA Leon, RT Granata, HK Dhah, JA Welles, ...
Bioorganic & medicinal chemistry letters 22 (19), 6252-6255, 2012
172012
Expression Changes in Epigenetic Gene Pathways Associated With One‐Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non‐Typical …
Y Zhu, CE Mordaunt, BP Durbin‐Johnson, MA Caudill, OV Malysheva, ...
Autism Research 14 (1), 11-28, 2021
152021
mtDNA depletion‐like syndrome in Wilson disease
V Medici, GV Sarode, E Napoli, GY Song, NM Shibata, AO Guimarães, ...
Liver International 40 (11), 2776-2787, 2020
92020
Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment
JS Mouat, X Li, K Neier, Y Zhu, CE Mordaunt, MA La Merrill, HJ Lehmler, ...
Environmental Research 220, 115227, 2023
82023
Comethyl: a network-based methylome approach to investigate the multivariate nature of health and disease
CE Mordaunt, JS Mouat, RJ Schmidt, JM LaSalle
Briefings in bioinformatics 23 (2), bbab554, 2022
72022
Effects of structural and electronic characteristics of chalcones on the activation of peroxisome proliferator-activated receptor gamma
JT Schott, CE Mordaunt, AJ Vargas, MA Leon, KH Chen, M Singh, ...
Chemical and Pharmaceutical Bulletin 61 (2), 229-236, 2013
32013
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
P Choudhary, GS Monasso, V Karhunen, J Ronkainen, G Mancano, ...
Molecular psychiatry 29 (2), 348-358, 2024
2024
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