Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis NA Scott, A Andrusaite, P Andersen, M Lawson, C Alcon-Giner, C Leclaire, ... Science translational medicine 10 (464), eaao4755, 2018 | 265 | 2018 |
Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome: an observational study C Alcon-Giner, MJ Dalby, S Caim, J Ketskemety, A Shaw, K Sim, ... Cell Reports Medicine 1 (5), 2020 | 191 | 2020 |
Leveraging multiple transcriptome assembly methods for improved gene structure annotation L Venturini, S Caim, GG Kaithakottil, DL Mapleson, D Swarbreck GigaScience 7 (8), giy093, 2018 | 161 | 2018 |
Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathogens RM Leggett, C Alcon-Giner, D Heavens, S Caim, TC Brook, M Kujawska, ... Nature microbiology 5 (3), 430-442, 2020 | 136 | 2020 |
Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors R Kiu, S Caim, S Alexander, P Pachori, LJ Hall Frontiers in microbiology 8, 2485, 2017 | 97 | 2017 |
Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny L Stewart, A Ford, V Sangal, J Jeukens, B Boyle, I Kukavica-Ibrulj, S Caim, ... Pathogens and disease 71 (1), 20-25, 2014 | 72 | 2014 |
Preterm infants harbour diverse Klebsiella populations, including atypical species that encode and produce an array of antimicrobial resistance- and virulence … Y Chen, TC Brook, CZ Soe, I O'neill, C Alcon-Giner, O Leelastwattanagul, ... Microbial genomics 6 (6), e000377, 2020 | 59 | 2020 |
Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants C Alcon-Giner, S Caim, S Mitra, J Ketskemety, U Wegmann, J Wain, ... BMC genomics 18, 1-15, 2017 | 59 | 2017 |
Preterm Infant-Associated Clostridium tertium, Clostridium cadaveris, and Clostridium paraputrificum Strains: Genomic and Evolutionary Insights R Kiu, S Caim, C Alcon-Giner, G Belteki, P Clarke, D Pickard, G Dougan, ... Genome Biology and Evolution 9 (10), 2707-2714, 2017 | 51 | 2017 |
Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth AM McKee, BM Kirkup, M Madgwick, WJ Fowler, CA Price, SA Dreger, ... Iscience 24 (9), 2021 | 42 | 2021 |
Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry … R Kiu, J Brown, H Bedwell, C Leclaire, S Caim, D Pickard, G Dougan, ... Animal Microbiome 1, 1-14, 2019 | 38 | 2019 |
The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding KR Hughes, Z Schofield, MJ Dalby, S Caim, L Chalklen, F Bernuzzi, ... The FASEB Journal 34 (5), 7075, 2020 | 33 | 2020 |
Bifidobacterium breve UCC2003 Exopolysaccharide Modulates the Early Life Microbiota by Acting as a Potential Dietary Substrate D Püngel, A Treveil, MJ Dalby, S Caim, IJ Colquhoun, C Booth, ... Nutrients 12 (4), 948, 2020 | 33 | 2020 |
Phylogenomic analysis of gastroenteritis-associated Clostridium perfringens in England and Wales over a 7-year period indicates distribution of clonal toxigenic … R Kiu, S Caim, A Painset, D Pickard, C Swift, G Dougan, AE Mather, ... Microbial Genomics 5 (10), e000297, 2019 | 30 | 2019 |
Perturbation of the gut microbiota by antibiotics results in accelerated breast tumour growth and metabolic dysregulation BM Kirkup, A McKee, KA Makin, J Paveley, S Caim, C Alcon-Giner, ... BioRxiv, 553602, 2019 | 28 | 2019 |
Bifidobacterium breve UCC2003 induces a distinct global transcriptomic program in neonatal murine intestinal epithelial cells R Kiu, A Treveil, LC Harnisch, S Caim, C Leclaire, D van Sinderen, ... IScience 23 (7), 2020 | 26 | 2020 |
Rapid MinION metagenomic profiling of the preterm infant gut microbiota to aid in pathogen diagnostics RM Leggett, C Alcon-Giner, D Heavens, S Caim, TC Brook, M Kujawska, ... BioRxiv 180406, 2017 | 24 | 2017 |
Streaming histogram sketching for rapid microbiome analytics WPM Rowe, AP Carrieri, C Alcon-Giner, S Caim, A Shaw, K Sim, JS Kroll, ... Microbiome 7, 1-13, 2019 | 22 | 2019 |
Microbiomes attached to fresh perennial ryegrass are temporally resilient and adapt to changing ecological niches SA Huws, JE Edwards, W Lin, F Rubino, M Alston, D Swarbreck, S Caim, ... Microbiome 9, 1-17, 2021 | 15 | 2021 |
Hydroxymethylation profile of cell-free DNA is a biomarker for early colorectal cancer NJ Walker, M Rashid, S Yu, H Bignell, CK Lumby, CM Livi, K Howell, ... Scientific Reports 12 (1), 16566, 2022 | 13 | 2022 |