| Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase QH Hu, RJ Liu, ZP Fang, J Zhang, YY Ding, M Tan, M Wang, W Pan, ... Scientific reports 3 (1), 2475, 2013 | 93 | 2013 |
| Inhibition of the CDK2 and Cyclin A complex leads to autophagic degradation of CDK2 in cancer cells J Zhang, Y Gan, H Li, J Yin, X He, L Lin, S Xu, Z Fang, B Kim, L Gao, ... Nature communications 13 (1), 2835, 2022 | 70 | 2022 |
| A Newly Identified Missense Mutation in FARS2 Causes Autosomal‐Recessive Spastic Paraplegia Y Yang, W Liu, Z Fang, J Shi, F Che, C He, L Yao, E Wang, Y Wu Human Mutation 37 (2), 165-169, 2016 | 67 | 2016 |
| The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL RJ Liu, M Zhou, ZP Fang, M Wang, XL Zhou, ED Wang Nucleic acids research 41 (16), 7828-7842, 2013 | 56 | 2013 |
| Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis E Zhang, L Jin, Y Wang, J Tu, R Zheng, L Ding, Z Fang, M Fan, ... Nature Communications 13 (1), 1135, 2022 | 51 | 2022 |
| Vertical sleeve gastrectomy confers metabolic improvements by reducing intestinal bile acids and lipid absorption in mice L Ding, E Zhang, Q Yang, L Jin, KM Sousa, B Dong, Y Wang, J Tu, X Ma, ... Proceedings of the National Academy of Sciences 118 (6), e2019388118, 2021 | 39 | 2021 |
| Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2′-O-methyltransferase M Zhou, T Long, ZP Fang, XL Zhou, RJ Liu, ED Wang RNA biology 12 (8), 900-911, 2015 | 38 | 2015 |
| Comprehensive analysis of the expression and prognostic value of CXC chemokines in colorectal cancer L Yu, X Yang, C Xu, J Sun, Z Fang, H Pan, W Han International immunopharmacology 89, 107077, 2020 | 31 | 2020 |
| Bile acid–mediated activation of brown fat protects from alcohol-induced steatosis and liver injury in mice M Fan, Y Wang, L Jin, Z Fang, J Peng, J Tu, Y Liu, E Zhang, S Xu, X Liu, ... Cellular and Molecular Gastroenterology and Hepatology 13 (3), 809-826, 2022 | 29 | 2022 |
| Tumor-suppressive function and mechanism of HOXB13 in right-sided colon cancer B Xie, B Bai, Y Xu, Y Liu, Y Lv, X Gao, F Wu, Z Fang, Y Lou, H Pan, W Han Signal transduction and targeted therapy 4 (1), 51, 2019 | 28 | 2019 |
| Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguity XL Zhou, ZP Fang, ZR Ruan, M Wang, RJ Liu, M Tan, FM Anella, ... Nucleic acids research 41 (21), 9825-9838, 2013 | 26 | 2013 |
| A minimalist mitochondrial threonyl-tRNA synthetase exhibits tRNA-isoacceptor specificity during proofreading XL Zhou, ZR Ruan, M Wang, ZP Fang, Y Wang, Y Chen, RJ Liu, G Eriani, ... Nucleic acids research 42 (22), 13873-13886, 2014 | 24 | 2014 |
| Translational quality control by bacterial threonyl-tRNA synthetases XL Zhou, Y Chen, ZP Fang, ZR Ruan, Y Wang, RJ Liu, MQ Xue, ED Wang Journal of Biological Chemistry 291 (40), 21208-21221, 2016 | 21 | 2016 |
| Coexistence of bacterial leucyl-tRNA synthetases with archaeal tRNA binding domains that distinguish tRNALeu in the archaeal mode ZP Fang, M Wang, ZR Ruan, M Tan, RJ Liu, M Zhou, XL Zhou, ED Wang Nucleic Acids Research 42 (8), 5109-5124, 2014 | 20 | 2014 |
| Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain QQ Ji, ZP Fang, Q Ye, CW Chi, ED Wang Nucleic Acids Research 45 (12), 7367-7381, 2017 | 19 | 2017 |
| Bile-ology: from bench to bedside L Jin, ZP Fang, M Fan, W Huang Journal of Zhejiang University-Science B 20 (5), 414-427, 2019 | 17 | 2019 |
| Identification of lethal mutations in yeast threonyl-tRNA synthetase revealing critical residues in its human homolog ZR Ruan, ZP Fang, Q Ye, HY Lei, G Eriani, XL Zhou, ED Wang Journal of Biological Chemistry 290 (3), 1664-1678, 2015 | 16 | 2015 |
| CAMK2γ antagonizes mTORC1 activation during hepatocarcinogenesis Z Meng, X Ma, J Du, X Wang, M He, Y Gu, J Zhang, W Han, Z Fang, X Gan, ... Oncogene 36 (17), 2446-2456, 2017 | 14 | 2017 |
| Degenerate connective polypeptide 1 (CP1) domain from human mitochondrial leucyl-tRNA synthetase Q Ye, M Wang, ZP Fang, ZR Ruan, QQ Ji, XL Zhou, ED Wang Journal of Biological Chemistry 290 (40), 24391-24402, 2015 | 14 | 2015 |
| A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity Q Huang, XL Zhou, QH Hu, HY Lei, ZP Fang, P Yao, ED Wang RNA 20 (9), 1440-1450, 2014 | 14 | 2014 |
