Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing HY Lee, K Zhou, AM Smith, CL Noland, JA Doudna Nucleic acids research 41 (13), 6568-6576, 2013 | 277 | 2013 |
Evolution of polyketide synthases in bacteria CP Ridley, HY Lee, C Khosla Proceedings of the National Academy of Sciences 105 (12), 4595-4600, 2008 | 234 | 2008 |
TRBP alters human precursor microRNA processing in vitro HY Lee, JA Doudna Rna 18 (11), 2012 | 203 | 2012 |
RNA–protein analysis using a conditional CRISPR nuclease HY Lee, RE Haurwitz, A Apffel, K Zhou, B Smart, CD Wenger, S Laderman, ... Proceedings of the National Academy of Sciences 110 (14), 5416-5421, 2013 | 93 | 2013 |
Bioassay-guided evolution of glycosylated macrolide antibiotics in Escherichia coli HY Lee, C Khosla PLoS biology 5 (2), e45, 2007 | 58 | 2007 |
Structural and Functional Studies on SCO1815: A β-Ketoacyl-Acyl Carrier Protein Reductase from Streptomyces coelicolor A3(2) Y Tang, HY Lee, Y Tang, CY Kim, I Mathews, C Khosla Biochemistry 45 (47), 14085-14093, 2006 | 38 | 2006 |
Structural and functional characterization of a hole–hole homodimer variant in a “knob-into-hole” bispecific antibody HM Zhang, C Li, M Lei, V Lundin, HY Lee, M Ninonuevo, K Lin, G Han, ... Analytical chemistry 89 (24), 13494-13501, 2017 | 37 | 2017 |
Improved precursor-directed biosynthesis in E. coli via directed evolution HY Lee, CJB Harvey, DE Cane, C Khosla The Journal of antibiotics 64 (1), 59-64, 2011 | 32 | 2011 |
Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway HY Lee, HS Chung, C Hang, C Khosla, CT Walsh, D Kahne, S Walker Journal of the American Chemical Society 126 (32), 9924-9925, 2004 | 28 | 2004 |
Exploring the biosynthetic potential of bimodular aromatic polyketide synthases Y Tang, TS Lee, HY Lee, C Khosla Tetrahedron 60 (35), 7659-7671, 2004 | 21 | 2004 |
Development of a bioassay to detect T-cell-activating impurities for T-cell-dependent bispecific antibodies HY Lee, E Contreras, AC Register, Q Wu, K Abadie, K Garcia, PY Wong, ... Scientific Reports 9 (1), 3900, 2019 | 19 | 2019 |
Bioassay Development for Bispecific Antibodies—Challenges and Opportunities AC Register, SS Tarighat, HY Lee International journal of molecular sciences 22 (10), 5350, 2021 | 17 | 2021 |
Physicochemical and functional characterization of differential CRISPR-Cas9 ribonucleoprotein complexes J Camperi, M Moshref, L Dai, HY Lee Analytical Chemistry 94 (2), 1432-1440, 2021 | 13 | 2021 |
“Two-in-One” approach for bioassay selection for dual specificity antibodies HY Lee, G Schaefer, I Lesaca, CV Lee, PY Wong, G Jiang Journal of Immunological Methods 448, 74-79, 2017 | 13 | 2017 |
Development and applications of AlphaScreen-based FcRn binding assay to characterize monoclonal antibodies Q Wu, HY Lee, PY Wong, G Jiang, H Gazzano-Santoro Journal of Immunological Methods 420, 31-37, 2015 | 13 | 2015 |
Characterization of a single reporter-gene potency assay for T-cell-dependent bispecific molecules HY Lee, A Register, J Shim, E Contreras, Q Wu, G Jiang MAbs 11 (7), 1245-1253, 2019 | 10 | 2019 |
Methods for assaying t-cell dependent bispecific antibodies HY Lee, G Jiang, PY Wong, K Carey US Patent 11,513,127, 2022 | 1 | 2022 |
Assessing a single-cell multi-omic analytic platform to characterize ex vivo-engineered T-cell therapy products M Moshref, JHH Lo, A McKay, J Camperi, J Schroer, N Ueno, S Wang, ... Frontiers in Bioengineering and Biotechnology 12, 1417070, 2024 | | 2024 |
Methods for assaying t-cell dependent bispecific antibodies HY Lee, G Jiang, PY Wong, K Carey US Patent App. 18/046,865, 2023 | | 2023 |
Evolution of macrolide antibiotics in Escherichia coli HY Lee Stanford University, 2008 | | 2008 |