| Cleavage and shedding of E-cadherin after induction of apoptosis U Steinhusen, J Weiske, V Badock, R Tauber, K Bommert, O Huber Journal of Biological Chemistry 276 (7), 4972-4980, 2001 | 345 | 2001 |
| Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS–SOS1 interaction RC Hillig, B Sautier, J Schroeder, D Moosmayer, A Hilpmann, ... Proceedings of the National Academy of Sciences 116 (7), 2551-2560, 2019 | 334 | 2019 |
| Estrogen receptor alpha up‐regulation and redistribution in human heart failure S Mahmoodzadeh, S Eder, J Nordmeyer, E Ehler, O Huber, P Martus, ... The FASEB journal 20 (7), 926-934, 2006 | 205 | 2006 |
| The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity J Weiske, O Huber Journal of Biological Chemistry 281 (37), 27356-27366, 2006 | 166 | 2006 |
| The histidine triad protein Hint1 interacts with Pontin and Reptin and inhibits TCF–β-catenin-mediated transcription J Weiske, O Huber Journal of cell science 118 (14), 3117-3129, 2005 | 154 | 2005 |
| The fate of desmosomal proteins in apoptotic cells J Weiske, T Schöneberg, W Schröder, M Hatzfeld, R Tauber, O Huber Journal of Biological Chemistry 276 (44), 41175-41181, 2001 | 154 | 2001 |
| Wnt signaling inhibits Forkhead box O3a-induced transcription and apoptosis through up-regulation of serum-and glucocorticoid-inducible kinase 1 M Dehner, M Hadjihannas, J Weiske, O Huber, J Behrens Journal of Biological Chemistry 283 (28), 19201-19210, 2008 | 146 | 2008 |
| The tumor suppressor Fhit acts as a repressor of β-catenin transcriptional activity J Weiske, KF Albring, O Huber Proceedings of the National Academy of Sciences 104 (51), 20344-20349, 2007 | 113 | 2007 |
| Zona occludens-2 inhibits cyclin D1 expression and cell proliferation and exhibits changes in localization along the cell cycle R Tapia, M Huerta, S Islas, A Avila-Flores, E Lopez-Bayghen, J Weiske, ... Molecular biology of the cell 20 (3), 1102-1117, 2009 | 97 | 2009 |
| Novel crosstalk to BMP signalling: cGMP‐dependent kinase I modulates BMP receptor and Smad activity R Schwappacher, J Weiske, E Heining, V Ezerski, B Marom, YI Henis, ... The EMBO journal 28 (11), 1537-1550, 2009 | 95 | 2009 |
| Nuclear Translocation Uncovers the Amyloid Peptide Aβ42 as a Regulator of Gene Transcription*♦ C Barucker, A Harmeier, J Weiske, B Fauler, KF Albring, S Prokop, ... Journal of Biological Chemistry 289 (29), 20182-20191, 2014 | 87 | 2014 |
| Isoform-selective ATAD2 chemical probe with novel chemical structure and unusual mode of action AE Fernández-Montalván, M Berger, B Kuropka, SJ Koo, V Badock, ... ACS chemical biology 12 (11), 2730-2736, 2017 | 80 | 2017 |
| Discovery and characterization of a highly potent and selective aminopyrazoline-based in vivo probe (BAY-598) for the protein lysine methyltransferase SMYD2 E Eggert, RC Hillig, S Koehr, D Stöckigt, J Weiske, N Barak, J Mowat, ... Journal of medicinal chemistry 59 (10), 4578-4600, 2016 | 76 | 2016 |
| A second protein kinase CK1-mediated step negatively regulates Wnt signalling by disrupting the lymphocyte enhancer factor-1/β-catenin complex A Hämmerlein, J Weiske, O Huber Cellular and molecular life sciences 62, 606-618, 2005 | 69 | 2005 |
| Berberine acts as a natural inhibitor of Wnt/β‐catenin signaling—Identification of more active 13‐arylalkyl derivatives KF Albring, J Weidemüller, S Mittag, J Weiske, K Friedrich, MC Geroni, ... Biofactors 39 (6), 652-662, 2013 | 68 | 2013 |
| Benzoisoquinolinediones as potent and selective inhibitors of BRPF2 and TAF1/TAF1L bromodomains L Bouché, CD Christ, S Siegel, AE Fernández-Montalván, SJ Holton, ... Journal of Medicinal Chemistry 60 (9), 4002-4022, 2017 | 55 | 2017 |
| Novel class of potent and cellularly active inhibitors devalidates MTH1 as broad-spectrum cancer target M Ellermann, A Eheim, F Rahm, J Viklund, J Guenther, M Andersson, ... ACS chemical biology 12 (8), 1986-1992, 2017 | 54 | 2017 |
| Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer SM Dieter, C Siegl, PL Codó, M Huerta, AL Ostermann-Parucha, E Schulz, ... Cell reports 36 (3), 2021 | 51 | 2021 |
| Butyrate induces intestinal sodium absorption via Sp3-mediated transcriptional up-regulation of epithelial sodium channels S Zeissig, A Fromm, J Mankertz, J Weiske, M Zeitz, M Fromm, ... Gastroenterology 132 (1), 236-248, 2007 | 48 | 2007 |
| Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2-d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5 D Nguyen, C Lemos, L Wortmann, K Eis, SJ Holton, U Boemer, ... Journal of medicinal chemistry 62 (2), 928-940, 2018 | 41 | 2018 |
