SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span TLA Kawahara, E Michishita, AS Adler, M Damian, E Berber, M Lin, ... Cell 136 (1), 62-74, 2009 | 1232 | 2009 |
Decoding global gene expression programs in liver cancer by noninvasive imaging E Segal, CB Sirlin, C Ooi, AS Adler, J Gollub, X Chen, BK Chan, ... Nature biotechnology 25 (6), 675-680, 2007 | 672 | 2007 |
Motif module map reveals enforcement of aging by continual NF-κB activity AS Adler, S Sinha, TLA Kawahara, JY Zhang, E Segal, HY Chang Genes & development 21 (24), 3244-3257, 2007 | 572 | 2007 |
Genetic regulators of large-scale transcriptional signatures in cancer AS Adler, M Lin, H Horlings, DSA Nuyten, MJ van de Vijver, HY Chang Nature genetics 38 (4), 421-430, 2006 | 274 | 2006 |
An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer ML McCleland, AS Adler, Y Shang, T Hunsaker, T Truong, D Peterson, ... Cancer research 72 (22), 5812-5823, 2012 | 200 | 2012 |
The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo R Dunn, DA Klos, AS Adler, L Hicke The Journal of cell biology 165 (1), 135-144, 2004 | 196 | 2004 |
The histone demethylase UTX enables RB-dependent cell fate control JK Wang, MC Tsai, G Poulin, AS Adler, S Chen, H Liu, Y Shi, HY Chang Genes & development 24 (4), 327-332, 2010 | 177 | 2010 |
Reversal of aging by NFκB blockade AS Adler, TLA Kawahara, E Segal, HY Chang Cell cycle 7 (5), 556-559, 2008 | 149 | 2008 |
CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency AS Adler, ML McCleland, T Truong, S Lau, Z Modrusan, TM Soukup, ... Cancer research 72 (8), 2129-2139, 2012 | 143 | 2012 |
Molecular framework for response to imatinib mesylate in systemic sclerosis L Chung, DF Fiorentino, MJ BenBarak, AS Adler, MM Mariano, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 139 | 2009 |
Lactate dehydrogenase B is required for the growth of KRAS-dependent lung adenocarcinomas ML McCleland, AS Adler, L Deming, E Cosino, L Lee, EM Blackwood, ... Clinical Cancer Research 19 (4), 773-784, 2013 | 134 | 2013 |
MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species S Ray, KR Atkuri, D Deb-Basu, AS Adler, HY Chang, LA Herzenberg, ... Cancer research 66 (13), 6598-6605, 2006 | 133 | 2006 |
An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth AS Adler, ML McCleland, S Yee, M Yaylaoglu, S Hussain, E Cosino, ... Genes & development 28 (10), 1068-1084, 2014 | 128 | 2014 |
Monoclonal antibody humanness score and its applications SH Gao, K Huang, H Tu, AS Adler BMC biotechnology 13, 1-12, 2013 | 110 | 2013 |
Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes AM Sääf, M Tengvall-Linder, HY Chang, AS Adler, CF Wahlgren, ... PloS one 3 (12), e4017, 2008 | 104 | 2008 |
The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167 SD Stamenova, R Dunn, AS Adler, L Hicke Journal of Biological Chemistry 279 (16), 16017-16025, 2004 | 100 | 2004 |
A transcriptional program mediating entry into cellular quiescence H Liu, AS Adler, E Segal, HY Chang PLoS Genetics 3 (6), e91, 2007 | 95 | 2007 |
CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression AS Adler, LE Littlepage, M Lin, TLA Kawahara, DJ Wong, Z Werb, ... Cancer research 68 (2), 506-515, 2008 | 89 | 2008 |
The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression LE Littlepage, AS Adler, H Kouros-Mehr, G Huang, J Chou, SR Krig, ... Cancer discovery 2 (7), 638-651, 2012 | 81 | 2012 |
Revealing targeted therapy for human cancer by gene module maps DJ Wong, DSA Nuyten, A Regev, M Lin, AS Adler, E Segal, ... Cancer research 68 (2), 369-378, 2008 | 77 | 2008 |