Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism EC Saunders, WW Ng, J Kloehn, JM Chambers, M Ng, MJ McConville PLoS pathogens 10 (1), e1003888, 2014 | 187 | 2014 |
Characterization of Metabolically Quiescent Leishmania Parasites in Murine Lesions Using Heavy Water Labeling J Kloehn, EC Saunders, S O’Callaghan, MJ Dagley, MJ McConville PLoS pathogens 11 (2), e1004683, 2015 | 145 | 2015 |
Functional and computational genomics reveal unprecedented flexibility in stage-specific Toxoplasma metabolism A Krishnan, J Kloehn, M Lunghi, A Chiappino-Pepe, BS Waldman, ... Cell host & microbe 27 (2), 290-306. e11, 2020 | 100 | 2020 |
Leishmania carbon metabolism in the macrophage phagolysosome-feast or famine? MJ McConville, EC Saunders, J Kloehn, MJ Dagley F1000Research 4 (F1000 Faculty Rev), 2015 | 88 | 2015 |
Using metabolomics to dissect host–parasite interactions J Kloehn, M Blume, SA Cobbold, EC Saunders, MJ Dagley, ... Current opinion in microbiology 32, 59-65, 2016 | 51 | 2016 |
Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse GM Kowalski, DP De Souza, ML Burch, S Hamley, J Kloehn, A Selathurai, ... Biochemical and biophysical research communications 462 (1), 27-32, 2015 | 50 | 2015 |
Overexpression of sphingosine kinase 1 in liver reduces triglyceride content in mice fed a low but not high-fat diet GM Kowalski, J Kloehn, ML Burch, A Selathurai, S Hamley, SAM Bayol, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 49 | 2015 |
Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii J Kloehn, RD Oppenheim, G Siddiqui, PJ De Bock, S Kumar Dogga, ... BMC biology 18, 1-26, 2020 | 42 | 2020 |
Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis GM Kowalski, S Hamley, A Selathurai, J Kloehn, DP De Souza, ... Scientific reports 6 (1), 27541, 2016 | 41 | 2016 |
A family of dual-activity glycosyltransferase-phosphorylases mediates mannogen turnover and virulence in Leishmania parasites MF Sernee, JE Ralton, TL Nero, LF Sobala, J Kloehn, MA Vieira-Lara, ... Cell host & microbe 26 (3), 385-399. e9, 2019 | 40 | 2019 |
Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal KX Lau, EA Mason, J Kie, DP De Souza, J Kloehn, D Tull, MJ McConville, ... Nature communications 11 (1), 2420, 2020 | 39 | 2020 |
Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages T Naderer, J Heng, EC Saunders, J Kloehn, TW Rupasinghe, TJ Brown, ... PLoS pathogens 11 (9), e1005136, 2015 | 37 | 2015 |
Supply and demand—heme synthesis, salvage and utilization by Apicomplexa J Kloehn, CR Harding, D Soldati‐Favre The FEBS journal 288 (2), 382-404, 2021 | 32 | 2021 |
Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization S Yildiz, JP Pereira Bonifacio Lopes, M Bergé, V González-Ruiz, D Baud, ... Elife 9, e53581, 2020 | 30 | 2020 |
Analysis of mammalian cell proliferation and macromolecule synthesis using deuterated water and gas chromatography-mass spectrometry VC Foletta, M Palmieri, J Kloehn, S Mason, SF Previs, MJ McConville, ... Metabolites 6 (4), 34, 2016 | 25 | 2016 |
eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatome B Weiss, GE Allen, J Kloehn, K Abid, P Jaquier-Gubler, JA Curran Nucleic Acids Research 49 (9), 5159-5176, 2021 | 24 | 2021 |
Vitamin and cofactor acquisition in apicomplexans: Synthesis versus salvage A Krishnan, J Kloehn, M Lunghi, D Soldati-Favre Journal of Biological Chemistry 295 (3), 701-714, 2020 | 23 | 2020 |
The metabolic pathways and transporters of the plastid organelle in Apicomplexa J Kloehn, CEM Lacour, D Soldati-Favre Current opinion in microbiology 63, 250-258, 2021 | 22 | 2021 |
Identification of Metabolically Quiescent Leishmania mexicana Parasites in Peripheral and Cured Dermal Granulomas Using Stable Isotope Tracing Imaging Mass … J Kloehn, BA Boughton, EC Saunders, S O’Callaghan, KJ Binger, ... MBio 12 (2), 10.1128/mbio. 00129-21, 2021 | 22 | 2021 |
Overexpression of striated muscle activator of Rho signaling (STARS) increases C2C12 skeletal muscle cell differentiation MA Wallace, PA Della Gatta, B Ahmad Mir, GM Kowalski, J Kloehn, ... Frontiers in physiology 7, 7, 2016 | 21 | 2016 |