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Arijit Dutta
Arijit Dutta
Senior Scientist, Ionis Pharmaceuticals, Inc.
在 ionisph.com 的电子邮件经过验证 - 首页
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引用次数
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年份
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex
A Dutta, B Eckelmann, S Adhikari, KM Ahmed, S Sengupta, A Pandey, ...
Nucleic acids research 45 (5), 2585-2599, 2017
992017
New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins
A Dutta, C Yang, S Sengupta, S Mitra, ML Hegde
Cellular and Molecular Life Sciences 72, 1679-1698, 2015
602015
The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: dominant …
PM Hegde, A Dutta, S Sengupta, J Mitra, S Adhikari, AE Tomkinson, ...
Journal of Biological Chemistry 290 (34), 20919-20933, 2015
562015
Human DNA glycosylase NEIL1’s interactions with downstream repair proteins is critical for efficient repair of oxidized DNA base damage and enhanced cell survival
ML Hegde, PM Hegde, D Arijit, I Boldogh, S Mitra
Biomolecules 2 (4), 564-578, 2012
392012
Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing
YS Kont, A Dutta, A Mallisetty, J Mathew, T Minas, C Kraus, ...
DNA repair 43, 38-47, 2016
332016
Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to …
S Sengupta, C Yang, ML Hegde, PM Hegde, J Mitra, A Pandey, A Dutta, ...
DNA repair 66, 1-10, 2018
322018
A tale of loops and tails: the role of intrinsically disordered protein regions in R-loop recognition and phase separation
LG Dettori, D Torrejon, A Chakraborty, A Dutta, M Mohamed, C Papp, ...
Frontiers in molecular biosciences 8, 691694, 2021
252021
A conserved Ctp1/CtIP C-terminal peptide stimulates Mre11 endonuclease activity
A Zdravković, JM Daley, A Dutta, T Niwa, Y Murayama, S Kanamaru, K Ito, ...
Proceedings of the National Academy of Sciences 118 (11), e2016287118, 2021
222021
Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions
ML Hegde, A Dutta, C Yang, AK Mantha, PM Hegde, A Pandey, ...
Oncotarget 7 (34), 54430, 2016
192016
DICER ribonuclease removes harmful R-loops
LP Camino, A Dutta, S Barroso, C Pérez-Calero, JN Katz, M García-Rubio, ...
Molecular cell 83 (20), 3707-3719. e5, 2023
132023
EEPD1 promotes repair of oxidatively-stressed replication forks
AS Jaiswal, HS Kim, OD Schärer, N Sharma, EA Williamson, G Srinivasan, ...
NAR cancer 5 (1), zcac044, 2023
82023
FMRP bridges R-loops and DHX9 through direct interactions
A Chakraborty, A Dutta, LG Dettori, L Gonzalez, X Xue, H Hehnly, P Sung, ...
BioRxiv, 2021
72021
Biochemical analysis of RNA–DNA hybrid and R-loop unwinding via motor proteins
A Dutta, Y Kwon, P Sung
R-Loops: Methods and Protocols, 305-316, 2022
42022
Senataxin: A putative RNA: DNA helicase mutated in ALS4—emerging mechanisms of genome stability in motor neurons
A Dutta, R Hromas, P Sung
Amyotrophic Lateral Sclerosis-Recent Advances and Therapeutic Challenges, 2020
42020
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells
AS Jaiswal, A Dutta, G Srinivasan, Y Yuan, D Zhou, M Shaheen, ...
Nucleic acids research 51 (22), 12224-12241, 2023
32023
Complex interplay between FMRP and DHX9 during DNA replication stress
A Chakraborty, A Dutta, LG Dettori, R Daoud, J Li, L Gonzalez, X Xue, ...
Journal of Biological Chemistry 300 (1), 2024
12024
Mechanism of SETX-BRCA1-BARD1 complex in resolution of R-loops and transcription-replication conflicts
P Sung, A Dutta, JH Ji, Q Fang, S Zhou, F Liang, J Nyalwidhe, E Dray, ...
2024
Characterizing the Repair of DNA Double-Strand Breaks: A Review of Surrogate Plasmid-Based Reporter Methods
A Dutta, J Mitra, PM Hegde, S Mitra, ML Hegde
Base Excision Repair Pathway: Methods and Protocols, 173-182, 2023
2023
Basic Principles of DNA Repair in Toxicology
A Dutta
Elsevier, 2018
2018
Understanding The Repair Mechanisms at Ionizing Radiation-induced Damage in The Human Genome
A Dutta
2016
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