Biliary organoids uncover delayed epithelial development and barrier function in biliary atresia SP Amarachintha, R Mourya, H Ayabe, L Yang, Z Luo, X Li, U Thanekar, ... Hepatology 75 (1), 89-103, 2022 | 49 | 2022 |
“Complimenting the complement”: mechanistic insights and opportunities for therapeutics in hepatocellular carcinoma A Malik, U Thanekar, S Amarachintha, R Mourya, S Nalluri, A Bondoc, ... Frontiers in oncology 10, 627701, 2021 | 38 | 2021 |
SCO2 mediates oxidative stress-induced glycolysis to oxidative phosphorylation switch in hematopoietic stem cells W Du, S Amarachintha, AF Wilson, Q Pang Stem Cells 34 (4), 960-971, 2016 | 35 | 2016 |
Mesenchymal COX 2‐PG secretome engages NR 4A‐WNT signalling axis in haematopoietic progenitors to suppress anti‐leukaemia immunity L Wu, S Amarachintha, J Xu, F Oley Jr, W Du British journal of haematology 183 (3), 445-456, 2018 | 32 | 2018 |
Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells W Du, S Amarachintha, AF Wilson, Q Pang Scientific reports 6 (1), 22167, 2016 | 25 | 2016 |
In vivo RNAi screen unveils PPARγ as a regulator of hematopoietic stem cell homeostasis M Sertorio, W Du, S Amarachintha, A Wilson, Q Pang Stem Cell Reports 8 (5), 1242-1255, 2017 | 22 | 2017 |
mTOR kinase inhibitor sensitizes T-cell lymphoblastic leukemia for chemotherapy-induced DNA damage via suppressing FANCD2 expression F Guo, J Li, S Zhang, W Du, S Amarachintha, J Sipple, J Phelan, ... Leukemia 28 (1), 203-206, 2014 | 22 | 2014 |
Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation W Du, S Amarachintha, J Sipple, J Schick, K Steinbrecher, Q Pang The Journal of Immunology 191 (5), 2806-2817, 2013 | 22 | 2013 |
Fanconi anemia mesenchymal stromal cells-derived glycerophospholipids skew hematopoietic stem cell differentiation through toll-like receptor signaling S Amarachintha, M Sertorio, A Wilson, X Li, Q Pang Stem cells 33 (11), 3382-3396, 2015 | 19 | 2015 |
The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation W Du, S Amarachintha, O Erden, A Wilson, Q Pang Oncotarget 7 (37), 60005, 2016 | 18 | 2016 |
Fancb deficiency impairs hematopoietic stem cell function W Du, S Amarachintha, O Erden, A Wilson, AR Meetei, PR Andreassen, ... Scientific Reports 5 (1), 18127, 2015 | 18 | 2015 |
Effect of Cdc42 domains on filopodia sensing, cell orientation, and haptotaxis SP Amarachintha, KJ Ryan, M Cayer, NS Boudreau, NM Johnson, ... Cellular signalling 27 (3), 683-693, 2015 | 18 | 2015 |
Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens S Amarachintha, E Harmel-Laws, KA Steinbrecher Scientific Reports 8 (1), 1521, 2018 | 16 | 2018 |
The immune receptor Trem1 cooperates with diminished DNA damage response to induce preleukemic stem cell expansion W Du, S Amarachintha, A Wilson, Q Pang Leukemia 31 (2), 423-433, 2017 | 15 | 2017 |
Persistent response of Fanconi anemia haematopoietic stem and progenitor cells to oxidative stress Y Li, S Amarachintha, AF Wilson, X Li, W Du Cell Cycle 16 (12), 1201-1209, 2017 | 14 | 2017 |
Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice KJ Betz, EA Maier, S Amarachintha, D Wu, EP Karmele, JM Kinder, ... PloS one 13 (6), e0198434, 2018 | 13 | 2018 |
Loss of Fancc impairs antibody-secreting cell differentiation in mice through deregulating the Wnt signaling pathway M Sertorio, S Amarachintha, A Wilson, Q Pang The Journal of Immunology 196 (7), 2986-2994, 2016 | 12 | 2016 |
Evolution of genomic sequence inhomogeneity at mid-range scales A Prakash, SS Shepard, J He, B Hart, M Chen, SP Amarachintha, ... Bmc Genomics 10, 1-11, 2009 | 10 | 2009 |
Activation of TGF‐β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease Z Liu, F Kong, JE Vallance, E Harmel‐Laws, S Amarachintha, ... Physiological Reports 5 (7), e13181, 2017 | 8 | 2017 |
LepR+ niche cell–derived AREG compromises hematopoietic stem cell maintenance under conditions of DNA repair deficiency and aging L Wu, Q Lin, S Chatla, S Amarachintha, AF Wilson, N Atale, ZJ Gao, ... Blood 142 (18), 1529-1542, 2023 | 6 | 2023 |