A humanized Lym-1 CAR with novel DAP10/DAP12 signaling domains demonstrates reduced tonic signaling and increased antitumor activity in B-cell lymphoma models L Zheng, L Ren, A Kouhi, LA Khawli, P Hu, HR Kaslow, AL Epstein Clinical Cancer Research 26 (14), 3694-3706, 2020 | 33 | 2020 |
NEO100 enables brain delivery of blood‒brain barrier impermeable therapeutics W Wang, NI Marín-Ramos, H He, S Zeng, HY Cho, SD Swenson, L Zheng, ... Neuro-oncology 23 (1), 63-75, 2021 | 27 | 2021 |
TAT-mediated acidic fibroblast growth factor delivery to the dermis improves wound healing of deep skin tissue in rat L Zheng, Q Hui, L Tang, L Zheng, Z Jin, B Yu, Z Wang, P Lin, W Yu, H Li, ... PLoS One 10 (8), e0135291, 2015 | 27 | 2015 |
High-Efficiency Expression of TAT-bFGF Fusion Protein in Escherichia coli and the Effect on Hypertrophic Scar Tissue X Jia, H Tian, L Tang, L Zheng, L Zheng, T Yang, B Yu, Z Wang, P Lin, ... PLoS One 10 (2), e0117448, 2015 | 22 | 2015 |
Spatio-temporal biodistribution of 89Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model NS Sta Maria, LA Khawli, V Pachipulusu, SW Lin, L Zheng, D Cohrs, X Liu, ... Scientific Reports 11 (1), 15077, 2021 | 17 | 2021 |
Generation of a monoclonal antibody to detect Elastin-Like Polypeptides A Kouhi, Z Yao, L Zheng, Z Li, P Hu, AL Epstein, JA MacKay Biomacromolecules 20 (8), 2942-2952, 2019 | 14 | 2019 |
Pharmacokinetics of topically applied recombinant human keratinocyte growth factor-2 in alkali-burned and intact rabbit eye J Cai, G Dou, L Zheng, T Yang, X Jia, L Tang, Y Huang, W Wu, X Li, ... Experimental eye research 136, 93-99, 2015 | 12 | 2015 |
Lym-1 chimeric antigen receptor T cells exhibit potent anti-tumor effects against B-cell lymphoma L Zheng, P Hu, B Wolfe, C Gonsalves, L Ren, LA Khawli, HR Kaslow, ... International journal of molecular sciences 18 (12), 2773, 2017 | 9 | 2017 |
Soluble expression of human insulin-like growth factor-1 with the assistance of SUMO fusion partner M Hui, F Li, L Tang, L Zheng, X Jia, P Lin, L Li, X Li, X Wang J. Chem. Pharm. Res 6 (4), 1059-1066, 2014 | 5 | 2014 |
Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by intraarterial NEO100 in mouse models of brain-localized malignancies W Wang, H He, S Zeng, HY Cho, RO Minea, SD Swenson, L Zheng, ... Journal of Neurosurgery 139 (3), 822-830, 2023 | 2 | 2023 |
Enhancing brain entry and therapeutic activity of chimeric antigen receptor T cells with intra-arterial NEO100 in a mouse model of CNS lymphoma W Wang, H He, L Zheng, S Zeng, HY Cho, A Kouhi, LA Khawli, L Chen, ... Journal of Neurosurgery 1 (aop), 1-9, 2023 | 1 | 2023 |
Simultaneous PET/MRI measurement of primary T cells biodistribution in naïve mice following adoptive cell transfer NS Maria, L Khawli, S Lin, V Pachipulusu, L Zheng, D Cohrs, A Epstein, ... Journal of Nuclear Medicine 60 (supplement 1), 277-277, 2019 | 1 | 2019 |
Preclinical characterization of CTL-1, A biosimilar anti-EGFR monoclonal antibody for cetuximab P Hu, R Graff, L Zheng, L Khawli, A Epstein SM J Bioequiv Availab 1 (1), 1003, 2017 | 1 | 2017 |
Lym-1 and lym-2 antibody compositions and improved car constructs AL Epstein, P Hu, L Zheng US Patent App. 18/141,116, 2024 | | 2024 |
Lym-1 and Lym-2 antibody compositions and improved car constructs AL Epstein, P Hu, L Zheng US Patent 11,667,715, 2023 | | 2023 |
Composições de anticorpo lym-1 e lym-2 e construções car aprimoradas AL Epstein, P Hu, L Zheng | | 2021 |
Lym-1 and lym-2 antibody compositions and improved car constructs AL Epstein, P Hu, L Zheng | | 2020 |
DAP10 and DAP12 signaling based CAR circumvents ligand-dependent tonic signaling and mediates potent anti-tumor response in vivo A Epstein, L Zheng JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |